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BackgroundNeutrophil-to-lymphocyte ratio (NLR) has been presented as a possible indicator associated with the outcomes of growing patients and an available predictor of inflammation. a comprehensive and large-scale single-center database. ResultsA total of 3,692 patients were included in this study.
In the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial, researchers examined the risk of ischemic events in patients with stable coronaryarterydisease. years, with 57.1% occurring within 30 days after CABG. years, with 21.1% occurring within 30 days after PCI.
The optimal surveillance strategy after percutaneous coronary intervention (PCI) for high-risk patients with multivessel or left main coronaryarterydisease (CAD) remains uncertain. The primary outcome was a composite of death from any cause, myocardial infarction, or hospitalization for unstable angina at 2 years.
The 2017 World Health Organization Fact Sheet highlights that coronaryarterydisease is the leading cause of death globally, responsible for approximately 30% of all deaths. In this context, machine learning (ML) technology is crucial in identifying coronaryarterydisease, thereby saving lives.
The registry will collect multi-site, real-world information on how the Plaque Analysis product provides enhanced patient insights, empowering physicians and helping to inform their medical management decisions for patients with suspected coronaryarterydisease (CAD). Observed outcomes and biomarkers are secondary endpoints.
Reversing or regressing coronaryarterydisease is possible. But can coronaryarterydisease be reversed with lifestyle measures, including changes to nutrition and exercise? In summary, the best outcome for plaque is to: Decrease in size Change from non calcified to calcified Develop a thick fibrous cap.
Together, the two companies will work to further the development and commercialization of Medis Quantitative Flow Ratio (Medis QFR), a non-invasive approach to the assessment of coronary physiology, as part of GE HealthCare’s interventional cardiology portfolio built around the Allia Platform. Accessed May 2024. Leon, Shubin Qiao, Gregg W.
Objective To explore trends in prognosis and use of glucose-lowering drugs (GLD) in patients with diabetes and coronaryarterydisease (CAD). Information on GLD (dispended 6 months before or after coronary angiography) was collected from the Swedish Prescribed Drug Registry.
BackgroundAcute psychological stress may induce physiological changes predisposing individuals to adverse health outcomes through hemodynamic and vascular effects. The outcome was a composite of cardiovascular death, nonfatal myocardial infarction, and heart failure hospitalizations during followup.
Left main coronaryarterydisease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. Preliminary evidence from trials focusing on patients with multivessel disease has hinted at diabetes as a potential modifier of treatment outcomes. Circulation.
Kramer, MD, FACC, discuss From JACC: National Trends in CoronaryArteryDisease Imaging: Associations With Health Care Outcomes and Costs. In this interview, Jonathan R. Weir-McCall, PhD, and Christopher M.
a provider of AI technology for coronaryarterydisease (CAD) management, recently introduced its new brand identity reflecting its focus on delivering clarity, precision and confidence in the prevention, diagnosisand treatment of CAD. References Centers for Disease Control and Prevention. Heart Disease Facts.
Coronaryarterydisease (CAD) is frequently found in this patient group and optimal management in these patients remains uncertain. Subsidiary outcomes included patient angina and breathlessness scores. After multivariate analysis, the presence of CAD had no effect on the primary outcome (HR 0.98, CI 0.68
Researchers have uncovered a significant genetic connection between Alzheimer's disease (AD) and several coronaryarterydisease (CAD) related disorders and lipid classes, offering opportunities to improve health outcomes across two of the more common causes of death in Australia.
The optimal management of concomitant chronic obstructive coronaryarterydisease (CAD) in transcatheter aortic valve replacement (TAVR) recipients remains a debated topic. While some advocate for pre-TAVR percutaneous coronary intervention, others adopt an expectant approach. Original article: Persits I et al.
Association of clonal haematopoiesis with heart failure incidence and outcomes: A systematic review and meta-analysis. Abstract Aims Clonal haematopoiesis (CH) is recognized as a significant risk factor for various non-haematologic conditions, including cardiovascular diseases. Clonal haematopoiesis and heart failure: a meta-analysis.
Ischemia and no obstructive coronaryarterydisease (INOCA) is increasingly recognized and associated with poor outcomes. The triglyceride-glucose (TyG) index is a reliable alternative measure of insulin resis.
Publication date: Available online 20 January 2025 Source: The American Journal of Cardiology Author(s): Robert C. Stoler, Minseob Jeong, Talha Akram, Alec Monhollen, David Fernandez Vazquez, Mufaddal Mamawala, Trenton A. Witt, Blake Bruneman, Sarah Weideman, Kennedy S. Adelman, Shalini Sharma, Yumna Furqan, Zachary P.
Objective In patients with complex coronaryarterydisease (CAD) undergoing cardiac surgery, myocardial protection might be impaired due to microvascular obstruction, resulting in myocardial injury and subsequent biomarker release.
Background The prognosis of myocardial ischaemia with no obstructive coronaryarterydisease (INOCA) and its underlying vasomotor disorders, vasospastic angina (VSA) and microvascular angina (MVA), is not well defined.
Researchers at Edith Cowan University's (ECU's) Centre for Precision Health have uncovered a significant genetic connection between Alzheimer's disease (AD) and several coronaryarterydisease (CAD) related disorders and lipid classes, offering opportunities to improve health outcomes across two of the more common causes of death in Australia.
(MedPage Today) -- ATLANTA -- Fractional flow reserve (FFR)-guided complete revascularization in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronaryarterydisease did not result in better outcomes compared.
BackgroundCoronary arterydisease is a global health concern that necessitates treatments, such as percutaneous coronary intervention (PCI) with drug-eluting stents (DES). Recent advancements in biodegradable polymer-coated DES have improved long-term outcomes by reducing neointimal hyperplasia.
Colchicine, a cheap and widely used anti-inflammatory has shown promise in improving cardiovascular outcomes. We aimed to perform a systematic review and meta-analysis to study the effects of colchicine in patients with symptomatic coronaryarterydisease (CAD) who have undergone PCI.
A common feedback I get is that people with existing coronaryarterydisease feel like it doesn’t apply to them. Arguably, applying the principles of prevention offers more bang for buck in the short term for people WITH coronaryarterydisease than those without coronaryarterydisease.
With this new funding, Cleerly will continue to scale its commercial growth and clinical evidence generation, helping health care professionals improve outcomes for patients across the coronary care pathway.
Deficits in health literacy are common in patients with coronaryarterydisease (CAD), and this is associated with increased morbidity and mortality. Five studies targeted interaction between patients and the health system; four of these reported improved outcomes, including through use of teach-back.
Coronary physiology assessment, including epicardial and microvascular investigations, is a fundamental tool in the contemporary management of patients with coronaryarterydisease. Coronary revascularisation guided by functional evaluation has demonstrated superiority over angiography-only-guided treatment.
Performing percutaneous coronary intervention (PCI) significantly improved outcomes in patients with stable coronaryarterydisease (CAD) and severe aortic stenosis selected for transcatheter aortic valve implantation (TAVI), according to late-breaking research presented in a Hot Line session today at ESC Congress 2024.
ObjectivesRevascularization in patients with severely reduced left ventricular function and coronaryarterydisease (CAD) is associated with a high perioperative risk.
A rare variant association study using exome sequencing data was performed on a machine learning-based marker for coronaryarterydisease (CAD). Our findings help us understand how these 17 genes are involved in coronaryarterydisease. Credit: Ron Do, PhD, and Ben Omega Petrazzini, BS, at Icahn Mount Sinai.
Since limb events are major drivers of morbidity in diabetic patients with peripheral (PAD) and coronaryarterydisease (CAD), does the addition of ticagrelor to background therapy of aspirin improve limb events?
BackgroundData on the predictive value of coronary computed tomography angiographyderived fractional flow reserve (CTFFR) for longterm outcomes are limited.Methods and ResultsA retrospective pooled analysis of individual patient data was performed. The primary outcome was major adverse cardiovascular events.
In patients with unprotected left main coronaryarterydisease (ULMCAD), this study compared the long-term prognosis of drug-eluting stent insertion guided by intravascular ultrasonography (IVUS) vs. angiography.
Coronaryarterydisease remains a leading cause of morbidity and mortality worldwide. Recent research has illuminated the role of total coronary atherosclerotic plaque activity across the entire coronaryarterial tree in predicting patient-level clinical outcomes.
Circulation: Cardiovascular Quality and Outcomes, Volume 17, Issue 12 , Page e011040, December 1, 2024. BACKGROUND:Posttraumatic stress disorder (PTSD) is associated with maladaptive dysregulation of stress response systems, which could lead to an increased risk of heart failure.
Precision Medicine: Personalizing Prevention for Better Outcomes Precision medicine provides tools to customize prevention and treatment plans based on individual risk factors. Key strategies include: Polygenic Risk Scores: Identifying Risk Early PRS helps identify young adults at high lifetime risk for coronaryarterydisease (CAD).
BackgroundLiterature suggests a bidirectional association between advanced hepatic fibrosis (AHF) and coronaryarterydisease (CAD). We evaluated the association of AHF with immune activation, systemic inflammation, and adverse outcomes in patients with CAD.Methods and ResultsA fibrosis‐4 index cutoff value ≥2.67
In this study, two independent cohorts were used to investigate for cardiovascular magnetic resonance (CMR) and genetic features of dilated cardiomyopathy (DCM) in individuals with coronaryarterydisease (CAD). NI-LGE was not independently associated with adverse clinical outcomes. vs. 6.7%, odds ratio 1.5,
Coronary three-vessel disease (CTVD) accounts for one-third of the overall incidence of coronaryarterydisease, with heightened mortality rates compared to single-vessel lesions, including common trunk lesion.
The role of triglyceride-glucose (TyG) index, an insulin resistance indicator, in glycemic management for diabetic patients with coronaryarterydisease (CAD) was still unknown. Therefore, we aimed to explore.
However, the long-term outcomes in patient with an intermediate stenosis received FFR have not yet been investigated comprehensively.Methods:We retrospective included 558 patients underwent both coronaryartery angiography (CAG) and FFR. Circulation, Volume 150, Issue Suppl_1 , Page A4144277-A4144277, November 12, 2024.
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