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Coronary Artery Disease Myocardial Infarction Outcomes 
Cardiology Update
MARCH 5, 2024
In the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial, researchers examined the risk of ischemic events in patients with stable coronary artery disease. years, with 57.1% occurring within 30 days after CABG. years, with 21.1% occurring within 30 days after PCI.
Cardiology Update
JUNE 16, 2024
Coronary artery disease remains a leading cause of morbidity and mortality worldwide. Recent research has illuminated the role of total coronary atherosclerotic plaque activity across the entire coronary arterial tree in predicting patient-level clinical outcomes. 3.72; P = 0.013).
Open Heart
MARCH 28, 2025
The primary outcomes of interest were mortality in ventricular and atrial arrhythmias, and later diagnosis of cardiac disease in atrial arrhythmias. However, it is linked to subsequent diagnosis of AF, coronary artery disease and myocardial infarction.
52 
Cardiology Update
MARCH 4, 2024
The optimal surveillance strategy after percutaneous coronary intervention (PCI) for high-risk patients with multivessel or left main coronary artery disease (CAD) remains uncertain. The primary outcome was a composite of death from any cause, myocardial infarction, or hospitalization for unstable angina at 2 years.
Cardiovascular Diabetology
AUGUST 6, 2024
Objective To explore trends in prognosis and use of glucose-lowering drugs (GLD) in patients with diabetes and coronary artery disease (CAD). Information on GLD (dispended 6 months before or after coronary angiography) was collected from the Swedish Prescribed Drug Registry. vs. 6.8%), myocardial infarction (7.7%
DAIC
MAY 14, 2024
Together, the two companies will work to further the development and commercialization of Medis Quantitative Flow Ratio (Medis QFR), a non-invasive approach to the assessment of coronary physiology, as part of GE HealthCare’s interventional cardiology portfolio built around the Allia Platform. Accessed May 2024. Leon, Shubin Qiao, Gregg W.
Cardiology Update
MARCH 25, 2024
Left main coronary artery disease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. Preliminary evidence from trials focusing on patients with multivessel disease has hinted at diabetes as a potential modifier of treatment outcomes.
122 
Journal of the American Heart Association
JANUARY 23, 2025
BackgroundAcute psychological stress may induce physiological changes predisposing individuals to adverse health outcomes through hemodynamic and vascular effects. The outcome was a composite of cardiovascular death, nonfatal myocardial infarction, and heart failure hospitalizations during followup.
Med Page Today
APRIL 10, 2024
(MedPage Today) -- ATLANTA -- Fractional flow reserve (FFR)-guided complete revascularization in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease did not result in better outcomes compared.
Dr. Paddy Barrett
APRIL 5, 2024
A common feedback I get is that people with existing coronary artery disease feel like it doesn’t apply to them. Arguably, applying the principles of prevention offers more bang for buck in the short term for people WITH coronary artery disease than those without coronary artery disease.
119 
Journal of the American Heart Association
MARCH 27, 2025
BackgroundRecent evidence highlights an increasing incidence of myocardial infarction in young women. The primary outcome was a composite of inhospital adverse events. Associations between multimorbidity patterns and outcomes were evaluated using multivariableadjusted logistic regression models.
Open Heart
OCTOBER 1, 2024
Background The prognosis of myocardial ischaemia with no obstructive coronary artery disease (INOCA) and its underlying vasomotor disorders, vasospastic angina (VSA) and microvascular angina (MVA), is not well defined.
American College of Cardiology
JULY 10, 2024
What is the outcome of contemporary revascularization strategies in patients presenting with myocardial infarction (MI) and multivessel coronary artery disease (CAD)?
Circulation
NOVEMBER 11, 2024
A meta-analysis was performed on primary outcomes of major adverse cardiac events (MACE) and all-cause mortality. A random-effects model was used for outcomes with high heterogeneity.Results:We included 4 RCTs with 3173 patients comparing FFR-guided CR with culprit-only PCI in patients with STEMI and multivessel coronary artery diseases.
Coronary Artery Disease Journal
OCTOBER 23, 2023
Background Acute myocardial infarction (AMI) is one of the most lethal complications of COVID-19 hospitalization. In this study, we looked for the occurrence of AMI and its effects on hospital outcomes among COVID-19 patients. The odds of adverse outcomes such as mortality (aOR 3.90, 95% CI: 3.48–4.36), Mortality (43.2%
52 
Frontiers in Cardiovascular Medicine
OCTOBER 7, 2024
ObjectivesRevascularization in patients with severely reduced left ventricular function and coronary artery disease (CAD) is associated with a high perioperative risk.
Journal of the American Heart Association
JANUARY 10, 2025
BackgroundData on the predictive value of coronary computed tomography angiographyderived fractional flow reserve (CTFFR) for longterm outcomes are limited.Methods and ResultsA retrospective pooled analysis of individual patient data was performed. The primary outcome was major adverse cardiovascular events.
Circulation: Cardiovascular Quality & Outcomes
NOVEMBER 20, 2024
Circulation: Cardiovascular Quality and Outcomes, Volume 17, Issue 12 , Page e011040, December 1, 2024. Secondary end points included cardiovascular death and nonfatal myocardial infarction with and without hospitalization for heart failure. Participants were followed up for a median time of 4.9
Open Heart
AUGUST 21, 2023
Background Insights on the differences in clinical outcomes, quality of life (QoL) and health resource utilisation (HRU) with different levels of care available to post-acute myocardial infarction (AMI) populations in rural and urban settings are limited. The adjusted incidence rate ratio was 0.92 (95% CI, 0.74
Nature Reviews - Cardiology
MAY 6, 2024
Nature Reviews Cardiology, Published online: 07 May 2024; doi:10.1038/s41569-024-01014-0 In 1993, Lincoff and Topol claimed that the thrombolytic treatment of ST-segment elevation myocardial infarction was suboptimal in many patients and gave an ‘illusion of reperfusion’.
Open Heart
JUNE 21, 2022
Background Several studies have demonstrated that complete revascularisation improves clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary disease. However, the optimal timing of non-culprit lesion revascularisation remains controversial.
Coronary Artery Disease Journal
SEPTEMBER 24, 2024
Introduction Despite advancements in coronary artery disease (CAD) management, major adverse cardiovascular events persist. Primary outcomes included myocardial infarction, stroke, major bleeding events, and all-cause mortality. 0.95; P = 0.002), myocardial infarction (HR, 0.81; 95% CI, 0.70–0.94;
Med Page Today
APRIL 8, 2024
(MedPage Today) -- ATLANTA -- Plasma-derived human apolipoprotein A1 (CSL112) infusions failed to improve outcomes for acute myocardial infarction (MI) patients with multivessel coronary artery disease and other cardiovascular risk factors, the.
Open Heart
JUNE 5, 2024
We aimed to investigate the prevalence and outcomes of patients with SMuRF-less ACS undergoing percutaneous coronary intervention (PCI) compared with those with SMuRFs. Patients with coronary artery disease were excluded. The primary outcome was 30-day mortality. vs 3.6%, p=0.019) and arrhythmia (11.2%
European Journal of Heart Failure
OCTOBER 5, 2023
In this study, two independent cohorts were used to investigate for cardiovascular magnetic resonance (CMR) and genetic features of dilated cardiomyopathy (DCM) in individuals with coronary artery disease (CAD). NI-LGE was not independently associated with adverse clinical outcomes. vs. 6.7%, odds ratio 1.5,
CardiacWire
MAY 10, 2024
A study in the Journal of Vascular Surgery revealed that adding FFRCT assessments to patient workups prior to peripheral artery disease surgeries has a massive impact on coronary artery disease detection, treatments, and long-term outcomes.
Open Heart
OCTOBER 27, 2023
Percutaneous coronary intervention (PCI) is widely adopted to treat chronic coronary artery disease. In this review, we discuss the current evidence in favour and against PCI in stable coronary syndromes and highlight the pitfalls of the available studies.
Coronary Artery Disease Journal
JUNE 10, 2024
Background Despite improvements in outcomes of ST elevation myocardial infarction (STEMI), ventricular septal rupture (VSR) remains a known complication, carrying high mortality. Methods The National Inpatient Sample database (2009–2020) was used to study trends in admissions and outcomes of post-STEMI VSR over time.
Coronary Artery Disease Journal
JANUARY 11, 2024
Myocardial infarction (MI) with non-obstructive coronary arteries (MINOCA) covers an expanding group of patients over recent years. Previous studies showed considerable risks of outcomes in this group. In this study, we aimed to investigate the long-term outcomes in very young patients with MINOCA.
Coronary Artery Disease Journal
NOVEMBER 20, 2023
Background: Gender-specific outcomes after percutaneous coronary interventions were studied by a number of research groups with different endpoints and cohorts of different ethnic extractions. Results: Overall, in the unmatched cohorts, accumulated target-lesion revascularization rates did not differ between both genders (2.7%
52 
All About Cardiovascular System and Disorders
MAY 26, 2024
It is now well known that even if a coronary artery is opened well after a myocardial infarction, with good flow in the epicardial coronary arteries, there could be impaired myocardial perfusion. Transit time is measured by saline bolus injection using a thermodilution technique. Banning, William F.
52 
Circulation: Cardiovascular Interventions
MARCH 17, 2025
High-quality, contemporary, multicenter data regarding clinical outcomes after PCI is scarce and poses a barrier to clinical decision-making for surgically ineligible patients. CONCLUSIONS:Ineligibility for surgical revascularization was associated with increased risk of long-term mortality after PCI.
Frontiers in Cardiovascular Medicine
FEBRUARY 23, 2024
Introduction The presence of non-coronary atherosclerosis (NCA) in patients with coronary artery disease is associated with a poor prognosis. We have studied whether NCA is also a predictor of poorer outcomes in patients undergoing coronary artery bypass grafting (CABG). vs. 9%, p < 0.001).
DAIC
MARCH 13, 2024
Smith Center for Outcomes Research in Cardiology and section chief of Interventional Cardiology at BIDMC. Even with advances in stent technology, patients with coronary in-stent restenosis continue to comprise approximately 10 percent of individuals undergoing angioplasty interventions each year. and Susan F. percent). “The
116 
Journal of the American Heart Association
MARCH 4, 2025
An increasing number of studies have shown the impact of social determinants of health (SDoHs) on different cardiovascular outcomes. In the setting of arrhythmias, specific SDoHs can increase the incidence of atrial fibrillation and adversely affect major outcomes in these patients.
DAIC
JANUARY 23, 2024
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
Coronary Artery Disease Journal
MAY 29, 2024
Background Despite advances in percutaneous coronary intervention (PCI) for ST segment elevation myocardial infarction (STEMI), in-hospital mortality remains a concern, highlighting the need for the identification of additional risk factors such as serum iron levels.
Frontiers in Cardiovascular Medicine
FEBRUARY 12, 2024
Background There is mounting data supporting the use of drug-coated balloons (DCB) not only for treatment of in-stent restenosis (ISR), but also in native coronary artery disease. Angiograms and outcomes were independently adjudicated. So far, paclitaxel-coated balloons represented the mainstay DCBs. IQR 12; 14.2)
Frontiers in Cardiovascular Medicine
JANUARY 23, 2024
were found to have obstructive coronary artery disease (CAD). of cases, CAG findings resulted in myocardial revascularization. Posttransplant MACE has a negative effect on grafts and patient outcomes. Asymptomatic obstructive CAD was observed in 70.2% Conclusion Asymptomatic CVD is largely prevalent in KTR.
64 Circulation
MARCH 11, 2024
BACKGROUND:Diabetes may be associated with differential outcomes in patients undergoing left main coronary revascularization with percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG). Circulation, Ahead of Print. PintHR=0.87) diabetes.
Coronary Artery Disease Journal
NOVEMBER 26, 2023
Aim Acute injury and subsequent remodelling responses to ST-segment elevation myocardial infarction (STEMI) are major determinants of clinical outcome. Current imaging and plasma biomarkers provide delayed readouts of myocardial injury and recovery.
Circulation: Cardiovascular Quality & Outcomes
FEBRUARY 3, 2025
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. The primary and secondary economic outcomes were total costs at 12 months and at 45 days, respectively, from the US health care system perspective.
40 
All About Cardiovascular System and Disorders
APRIL 21, 2024
FAME study showed that at one year follow up, rate of major adverse coronary events was reduced by approximately 30% by routinely measuring FFR. Routine FFR measurement probably lead to more judicious use of stents and improved outcomes. They had lower rates of mortality or myocardial infarction. Cut off FFR was 0.8
Circulation: Cardiovascular Interventions
NOVEMBER 28, 2023
The primary end point was target vessel failure defined as a composite of cardiac death, target vessel–related myocardial infarction, or clinically driven target vessel revascularization.Results:At a median follow-up of 2.1 years (interquartile range 1.1 versus 25.1%; hazard ratio, 0.31 [95% CI, 0.13–0.76];P=0.010). 0.76];P=0.010).
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