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Coronaryarterydisease remains a leading cause of morbidity and mortality worldwide. Recent research has illuminated the role of total coronary atherosclerotic plaque activity across the entire coronaryarterial tree in predicting patient-level clinical outcomes. 4.39; P = 0.002) myocardialinfarctions.
In the ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) trial, researchers examined the risk of ischemic events in patients with stable coronaryarterydisease. years, with 57.1% occurring within 30 days after CABG. Original article: Redfors B et al.
The optimal surveillance strategy after percutaneous coronary intervention (PCI) for high-risk patients with multivessel or left main coronaryarterydisease (CAD) remains uncertain. The primary outcome was a composite of death from any cause, myocardialinfarction, or hospitalization for unstable angina at 2 years.
(MedPage Today) -- Influenza infection was associated with an increased risk of acute myocardialinfarction (MI), especially for those without a prior hospitalization for coronaryarterydisease (CAD), according to a Dutch observational case series.
Objective To explore trends in prognosis and use of glucose-lowering drugs (GLD) in patients with diabetes and coronaryarterydisease (CAD). Information on GLD (dispended 6 months before or after coronary angiography) was collected from the Swedish Prescribed Drug Registry. vs. 6.8%), myocardialinfarction (7.7%
Together, the two companies will work to further the development and commercialization of Medis Quantitative Flow Ratio (Medis QFR), a non-invasive approach to the assessment of coronary physiology, as part of GE HealthCare’s interventional cardiology portfolio built around the Allia Platform.
Both the COMPLETE and PRAMI trial findings supported the benefits of complete revascularization over culprit-only percutaneous coronary intervention (PCI) in patients presenting with myocardialinfarction (MI) and multivessel coronaryarterydisease.
Mediation analyses were performed to assess the proportion mediated by MDD. Results Genetically predicted insomnia, short sleep, daytime napping and daytime sleepiness increased the risk of CVDs, with the OR ranging from 1.24 (95% CI 1.06 to 1.45) for insomnia on stroke to 1.55 (95% CI 1.28 to 1.89) for insomnia on MI.
Hemodynamic reactivity, changes in endothelial function, and vasoconstriction during mental stress were evaluated using changes in ratepressure product, brachial artery flowmediated vasodilation, and peripheral arterial tonometry, respectively. A total of 629 participants were included.
A common feedback I get is that people with existing coronaryarterydisease feel like it doesn’t apply to them. Arguably, applying the principles of prevention offers more bang for buck in the short term for people WITH coronaryarterydisease than those without coronaryarterydisease.
Patients with ST-segment elevation myocardialinfarction (STEMI) and complex coronaryarterydisease (CAD) face a poor prognosis, including increased heart failure (HF) risk.
Introduction Coronaryarterydisease (CAD) is a highly heritable and multifactorial disease. Numerous genome-wide association studies (GWAS) facilitated the construction of polygenic risk scores (PRS) for predicting future incidence of CAD, however, exclusively in European populations.
A random-effects model was used for outcomes with high heterogeneity.Results:We included 4 RCTs with 3173 patients comparing FFR-guided CR with culprit-only PCI in patients with STEMI and multivessel coronaryarterydiseases. The pooled results of the 4 RCTs showed that MACE (RR=0.66; 95% CI [0.45, 0.99]; p=0.01; 16.8%
We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronaryarterydisease. Analysis of inflammatory biomarkers and coronary CTA was also performed at baseline and 4 weeks after treatment.
ObjectivesRevascularization in patients with severely reduced left ventricular function and coronaryarterydisease (CAD) is associated with a high perioperative risk.
1 Atherosclerosis is a systemic disease that affects multiple vascular regions and is particularly severe in PAD patients, where up to 80 percent suffer from concurrent coronaryarterydisease (CAD), historically linked with a mortality rate exceeding 50 percent within five years.
(MedPage Today) -- ATLANTA -- Fractional flow reserve (FFR)-guided complete revascularization in patients with ST-segment elevation myocardialinfarction (STEMI) and multivessel coronaryarterydisease did not result in better outcomes compared.
What is the outcome of contemporary revascularization strategies in patients presenting with myocardialinfarction (MI) and multivessel coronaryarterydisease (CAD)?
Coronary computed tomography angiography (CCTA) is associated with a similar risk for cardiovascular death and myocardialinfarction as direct invasive coronary angiography (ICA) for initial assessment of suspected stable coronaryarterydisease (CAD), according to a review published online June 6 in the Annals of Internal Medicine.
BackgroundRisk stratification of patients with symptomatic nonobstructive coronaryarterydisease remains uncertain. in all 3 coronaryarteries on coronary angiography. Journal of the American Heart Association, Ahead of Print. A total of 490 patients were included.
BackgroundRecent evidence highlights an increasing incidence of myocardialinfarction in young women. years]) admitted to the China Chest Pain Center Database between 2016 and 2021.
Background The diagnostic performance of non-invasive imaging techniques for detecting obstructive coronaryarterydisease (CAD) in patients with a history of myocardialinfarction or percutaneous coronary intervention has not been comprehensively evaluated.
Left main coronaryarterydisease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. However, the comparative long-term efficacy of percutaneous coronary intervention (PCI) versus coronaryartery bypass grafting (CABG) in patients with these conditions remains unclear.
Background The prognosis of myocardial ischaemia with no obstructive coronaryarterydisease (INOCA) and its underlying vasomotor disorders, vasospastic angina (VSA) and microvascular angina (MVA), is not well defined.
We investigated whether PTSD was independently associated with first and recurrent heart failure hospitalizations in the setting of coronaryartery disease.METHODS:Individuals with stable coronaryarterydisease and without heart failure at baseline were enrolled in 2 parallel prospective cohort studies in metropolitan Atlanta, GA.
The goal of the FIRE trial was to evaluate multivessel revascularization guided by coronary physiology compared with culprit-only revascularization among elderly patients with acute myocardialinfarction (MI) and multivessel coronaryarterydisease (CAD).
Long-term treatment with beta-blockers may not lower the risk of death or myocardialinfarction (MI) in patients with MI, a preserved left ventricular ejection fraction (LVEF) of ≥50% and coronaryarterydisease, according to the results of the REDUCE-AMI study, presented during a Late-Breaking Clinical Trial session at ACC.24
The benefit of beta-blockers after myocardialinfarction was established before the advent of reperfusion and percutaneous coronary intervention and the availability of effective secondary preventive medications.1-3
BackgroundIn Thailand, access to specific pharmaceuticals and medical devices for ST-elevation myocardialinfarction (STEMI) patients is restricted within certain healthcare systems, leading to inequalities in the quality of medical care among different healthcare systems.
The presence of atrial arrhythmias during stress testing at all time points was also associated with later diagnosis of coronaryarterydisease or myocardialinfarction: OR 1.82 (95% CI 1.09, 3.03), p=0.02. However, it is linked to subsequent diagnosis of AF, coronaryarterydisease and myocardialinfarction.
Background Acute myocardialinfarction (AMI) is one of the most lethal complications of COVID-19 hospitalization. In this study, we looked for the occurrence of AMI and its effects on hospital outcomes among COVID-19 patients. Methods Data from the 2020 California State Inpatient Database was used retrospectively.
Background Several studies have demonstrated that complete revascularisation improves clinical outcomes in patients with ST-segment elevation myocardialinfarction (STEMI) and multivessel coronarydisease. However, the optimal timing of non-culprit lesion revascularisation remains controversial.
Myocardialinfarction with non-obstructive coronaryarteries (MINOCA) defines a heterogeneous group of atherosclerotic and non-atherosclerotic conditions, causing myocardial injury in the absence of obstructive coronaryarterydisease.
Nature Reviews Cardiology, Published online: 07 May 2024; doi:10.1038/s41569-024-01014-0 In 1993, Lincoff and Topol claimed that the thrombolytic treatment of ST-segment elevation myocardialinfarction was suboptimal in many patients and gave an ‘illusion of reperfusion’.
Introduction Elevated peak cardiac troponin levels have been linked with increased morbidity and mortality in patients with acute myocardialinfarction (AMI). Immature Platelets are young and relatively large platelets that are hyper-reactive and pro-thrombotic compared to regular platelets.
The secondary outcome was death or nonfatal myocardialinfarction. Predictive abilities for outcomes were compared among 3 models (model 1, constructed using clinical variables; model 2, model 1+coronary computed tomography angiographyderived anatomical parameters; and model 3, model 2+CTFFR).
(MedPage Today) -- ATLANTA -- Plasma-derived human apolipoprotein A1 (CSL112) infusions failed to improve outcomes for acute myocardialinfarction (MI) patients with multivessel coronaryarterydisease and other cardiovascular risk factors, the.
(MedPage Today) -- The latest evidence moves the needle closer in favor of one-go complete revascularization for people with acute myocardialinfarction (MI) and multivessel coronaryarterydisease, according to an updated network meta-analysis.
Background Insights on the differences in clinical outcomes, quality of life (QoL) and health resource utilisation (HRU) with different levels of care available to post-acute myocardialinfarction (AMI) populations in rural and urban settings are limited.
Background:Myocardial infarction with nonobstructive coronaryarterydisease (MINOCA) is a special syndrome with clear evidence of myocardial ischemia, but no clear stenosis of coronaryartery imaging sign. Circulation, Volume 150, Issue Suppl_1 , Page A4143007-A4143007, November 12, 2024.
BackgroundCoronary computed tomography angiography is increasingly used as the first‐line test for suspected coronaryarterydisease. The overall mortality, cardiac deaths, myocardialinfarctions, and hospitalizations for unstable angina were acquired from national registry data for 1 to 10 years of follow‐up (median, 4 years).
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