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Safety and possible anti-inflammatory effect of paclitaxel associated with LDL-like nanoparticles (LDE) in patients with chronic coronary artery disease: a double-blind, placebo-controlled pilot study

Frontiers in Cardiovascular Medicine

We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronary artery disease. Clinical and laboratory safety evaluations were made at baseline and every 3 weeks until the end of the study.

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Patient-specific in silico 3D coronary model in cardiac catheterisation laboratories

Frontiers in Cardiovascular Medicine

Coronary artery disease is caused by the buildup of atherosclerotic plaque in the coronary arteries, affecting the blood supply to the heart, one of the leading causes of death around the world.

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Coronary Artery Calcification: Current Concepts and Clinical Implications

Circulation

Nevertheless, the relationship between CAC and the susceptibility of a plaque to provoke a thrombotic event remains incompletely understood. Nevertheless, the relationship between CAC and the susceptibility of a plaque to provoke a thrombotic event remains incompletely understood.

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Sex-Specific Association Between Perivascular Inflammation and Plaque Vulnerability

Circulation: Cardiovascular Imaging

BACKGROUND:It is not known whether there is a sex difference in the association between perivascular inflammation and plaque vulnerability. All images were analyzed at a core laboratory. plaques per patient) and 784 lesions in 327 men (2.4 plaques per patient). plaques per patient) and 784 lesions in 327 men (2.4

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