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Safety and possible anti-inflammatory effect of paclitaxel associated with LDL-like nanoparticles (LDE) in patients with chronic coronary artery disease: a double-blind, placebo-controlled pilot study

Frontiers in Cardiovascular Medicine

We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronary artery disease. Clinical and laboratory safety evaluations were made at baseline and every 3 weeks until the end of the study.

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BIDMC-led Trial Leads to FDA approval of Coronary Drug-coated Balloons

DAIC

There's growing sentiment that drug-coated balloons could address an unmet clinical need among patients with coronary artery disease in the United States.” Each year, millions of people around the world undergo coronary angioplasty, a non-surgical intervention to treat blockages in the arteries that supply blood to the heart.

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The First 60 Minutes of a Heart Attack: The Golden Hour

Wellnest

Three coronary arteries supply blood to the heart. When one of these arteries becomes completely blocked by a blood clot, it results in a heart attack, also known as MI (Myocardial infarction). The accumulation of cholesterol, foam cells, fibrous tissue, and calcium mainly causes the narrowing of coronary arteries.

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A "normal ECG" on a busy night

Dr. Smith's ECG Blog

The patient was in his 50s with history of hypertension, diabetes, seizure disorder, and smoking, but no known coronary artery disease. As was the more reliable laboratory troponin T (0.00 418 of these 1788 (23%) had acute coronary occlusion. Alas, it was of course negative. Ongoing high lateral OMI.