DAIC

MARCH 27, 2025

In 2024, the FDA approved Flyrcado for patients with known or suspected coronary artery disease (CAD), delivering higher diagnostic efficacy compared to single-photon emission computed tomography (SPECT) i myocardial perfusion imaging (MPI), the predominant procedure used in nuclear cardiology today. 2023 Oct, 82 (16) 15981610.

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Journal of the American Heart Association

JANUARY 23, 2025

Hemodynamic reactivity, changes in endothelial function, and vasoconstriction during mental stress were evaluated using changes in ratepressure product, brachial artery flowmediated vasodilation, and peripheral arterial tonometry, respectively.

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Coronary Artery Disease Outcomes Myocardial Infarction Risk Factors 56

Medical Xpress - Cardiology

MAY 17, 2024

Coronary artery bypass grafting (CABG) is a surgical procedure that improves blood flow to the heart tissue and can effectively treat myocardial ischemia caused by coronary artery disease.

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Coronary Artery Bypass Graft Coronary Artery Disease Research Ischemia 96

DAIC

MARCH 28, 2024

milla1cf Thu, 03/28/2024 - 07:00 March 28, 2024 — Cleerly , the company on a mission to create a new standard of care to aid in the diagnosis of heart disease, shared findings from a study published online in the Journal of the American College of Cardiology: Cardiovascular Imaging on March 13, 2024. J Am Coll Cardiol. 2024.01.007.

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Ischemia Chest Pain Atherosclerosis Coronary Artery Disease 110

DAIC

MAY 8, 2024

1 Atherosclerosis is a systemic disease that affects multiple vascular regions and is particularly severe in PAD patients, where up to 80 percent suffer from concurrent coronary artery disease (CAD), historically linked with a mortality rate exceeding 50 percent within five years. Journal of Vascular Surgery, Mar.

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Coronary Artery Disease Chest Pain Ischemia Myocardial Infarction 111

Dr. Smith's ECG Blog

MAY 23, 2014

This case shows a CT image of subendocardial ischemia. ng/mL (slightly elevated) and his symptoms could not be controlled with nitroglycerin, so he was taken to the cath lab and found to have: --Severe 3 vessel Coronary artery disease involving the LM. The image is shown at the bottom after the case presentation.

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CardiacWire

MAY 10, 2024

A study in the Journal of Vascular Surgery revealed that adding FFRCT assessments to patient workups prior to peripheral artery disease surgeries has a massive impact on coronary artery disease detection, treatments, and long-term outcomes.

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Coronary Artery Disease Peripheral Arterial Disease Ischemia Myocardial Infarction 59

EMS 12-Lead

APRIL 9, 2024

Many of the changes seen are reminiscent of LVH with “strain,” and downstream Echo may very well corroborate such a suspicion, but since the ECG isn’t the best tool for definitively establishing the presence of LVH, we must favor a subendocardial ischemia pattern, instead. Type I ischemia. Type II ischemia.

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Cardiovascular Diabetology

JULY 4, 2024

Owing to its unique location and multifaceted metabolic functions, epicardial adipose tissue (EAT) is gradually emerging as a new metabolic target for coronary artery disease risk stratification. Microvascular.

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DAIC

APRIL 11, 2024

PCI is commonly used to open blocked arteries to treat significant myocardial ischemia , which occurs when the heart muscle does not get enough oxygenated blood. To test this strategy, researchers enrolled 1,606 patients treated for coronary artery disease at 15 centers in four countries.

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DAIC

MARCH 27, 2024

Food and Drug Administration (FDA) for its DynamX BTK System, a novel, adaptive implant for use in the treatment of narrowed or blocked vessels below-the-knee (BTK) in patients with chronic limb-threatening ischemia (CLTI). The natural history of untreated severe or critical limb ischemia. 2013;382(9901):1329-1340. J Vasc Surg.

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Peripheral Arterial Disease Ischemia Technology Coronary Artery Disease 111

DAIC

JANUARY 3, 2024

Traditional methods of non-invasive ischemia testing (stress EKG , stress echo, SPECT , PET , direct-to-cath) can result in false negatives 20-30 percent of the time, which can lead to undetected disease, and false positives over 50 percent of the time, which can lead to unnecessary invasive procedures.

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DAIC

MARCH 20, 2024

The Freesolve BTK RMS is designed for individuals suffering from chronic limb-threatening ischemia (CLTI). CLTI is the most severe form of peripheral arterial disease (PAD), estimated to affect 11% of the 200 million people suffering from PAD globally. Jörg Pochert, President of Vascular Intervention at Biotronik.

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Dr. Smith's ECG Blog

NOVEMBER 22, 2023

Important point: when there is diffuse subendocardial ischemia but no OMI, a wall motion abnormality will not necessarily be present. They agreed ischemia was likely in the setting of demand given DKA and infection. That this is all demand ischemia is unlikely. Lung exam showed diffuse B lines bilaterally. Aslanger's pattern.

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Chest Pain Ischemia Echocardiogram Myocardial Infarction 119

Circulation

NOVEMBER 11, 2024

Background:Myocardial infarction with nonobstructive coronary artery disease (MINOCA) is a special syndrome with clear evidence of myocardial ischemia, but no clear stenosis of coronary artery imaging sign. Circulation, Volume 150, Issue Suppl_1 , Page A4143007-A4143007, November 12, 2024.

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Coronary Artery Disease Atrial Fibrillation Myocardial Infarction Ischemia 40

ECG Guru

SEPTEMBER 10, 2023

The most likely cause of this type of polymorphic ventricular tachycardia during a stress EKG is cardiac ischemia/coronary artery disease. The QT interval of the sinus beats does not appear prolonged, thus ruling out Torsades de Pointes tachycardia.

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Tachycardia Coronary Artery Disease Ischemia 52

DAIC

MAY 16, 2024

Risk factors for PAD include smoking; having Type 1 or Type 2 diabetes, high blood pressure, high cholesterol, chronic kidney disease, atherosclerosis in other parts of the body (such as coronary artery disease); and being age 75 years or older. It has been estimated that less than 5% of patients with PAD in the U.S.

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Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

DAIC

MARCH 6, 2024

milla1cf Wed, 03/06/2024 - 18:48 March 6, 2024 — Cleerly , the company on a mission to create a new standard of care to aid in the diagnosis of heart disease, has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration ( FDA ) for its Coronary Artery Disease ( CAD ) Staging System.

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Heart Disease Heart attacks Heart Attack Technology 105

Frontiers in Cardiovascular Medicine

MARCH 17, 2024

Background Refractory angina (RA) is a chronic condition characterized by the presence of debilitating angina symptoms due to established reversible ischemia in the presence of obstructive coronary artery disease (CAD).

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Angina Quality of Life Coronary Artery Disease Ischemia 64

Dr. Smith's ECG Blog

DECEMBER 7, 2023

I quickly reviewed the patient’s records and saw that she was a 53 year old woman with a history of BMI 40, but no other identifiable risk factors for coronary artery disease. This proves effective treatment of the recurrent ischemia. The patient had no further symptoms of ischemia.

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DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronary artery disease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3

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Cardiovascular Disease Heart attacks Heart Attack Coronary Artery Disease 111

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

The diagnostic coronary angiogram identified only minimal coronary artery disease, but there was a severely calcified, ‘immobile’ aortic valve. DISCUSSION: The 12-lead EKG EMS initially obtained for this patient showed severe ischemia, with profound "infero-lateral" ST depression and reciprocal ST elevation in lead aVR.

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Dr. Smith's ECG Blog

OCTOBER 20, 2024

The first task when assessing a wide complex QRS for ischemia is to identify the end of the QRS. The ST segment changes are compatible with severe subendocardial ischemia which can be caused by type I MI from ACS or potentially from type II MI (non-obstructive coronary artery disease with supply/demand mismatch).

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Cardiogenic Shock Ischemia Chest Pain Cardiac Arrest 129

Dr. Smith's ECG Blog

NOVEMBER 5, 2023

By Magnus Nossen, edits by Grauer and Smith The patient is a 70-something female with DMII, HTN and an extensive prior history of coronary artery disease and myocardial infarctions. ECG#1 Assessing ischemia on an ECG with wide QRS complexes (AIVR, ventricular pacing, BBB, etc) can be challenging. What do you think?

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Dr. Paddy Barrett

NOVEMBER 28, 2023

In general, there is no debate here regarding the need for stenting a coronary artery. Share Stenting In Stable Coronary Artery Disease The real debate relates to the role of stenting in the setting of a severely narrow coronary artery outside the setting of a heart attack. Makes total sense.

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Stent Stents Heart attacks Heart Attack 52

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Introduction The use of contemporary drug-eluting stents (DES) has significantly improved outcomes of patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI). had multivessel disease (MVD) and in 3.3% At 1 year, only two (0.5%) subjects presented ischemia-driven TLR.

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Frontiers in Cardiovascular Medicine

OCTOBER 9, 2024

In this study, we aimed to evaluate the prognostic value of ΔLVEF when acquired by SPECT G-MPI in patients with coronary artery disease (CAD) and a LVEFStress   0% and ΔLVEF ≤ 0%), and survival analyses were conducted.

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Coronary Artery Disease Myocardial Infarction Ischemia Hospital 52

Frontiers in Cardiovascular Medicine

FEBRUARY 18, 2025

ObjectiveA significant proportion (85%) of low-risk non-ST-elevation acute coronary syndrome (NSTE-ACS) patients do not receive objective confirmation of ischemia by stress echocardiography (SE), yet remain a healthcare burden due to lower long-term survival and overuse of medical services.

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Chest Pain Exercise Angina Coronary Artery Disease 52

All About Cardiovascular System and Disorders

APRIL 21, 2024

indicates inducible ischemia while an FFR above 0.80 excludes ischemia in 90% of cases. FAME study showed that at one year follow up, rate of major adverse coronary events was reduced by approximately 30% by routinely measuring FFR. There is a strong correlation between FFR and inducible myocardial ischemia. in the study.

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MIBHS

OCTOBER 31, 2024

Heart Valve Disease If one or more heart valves are not functioning correctly, it can cause blood to flow backward, putting extra pressure on the heart, which may cause it to expand to compensate for the inefficiency. This may result in ischemia (lack of oxygen to the heart muscle), causing parts of the heart to weaken and enlarge.

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All About Cardiovascular System and Disorders

APRIL 13, 2024

This highlights the need for serial ECGs in acute coronary syndrome as initial ECGs may be near normal even in those with severe disease. Classical electrocardiographic pattern in left main coronary artery disease is ST elevation in aVR with extensive ST depression in other leads, most prominent in I, II and V4-V6.

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Stenosis Coronary Artery Bypass Graft Coronary Artery Disease Document 52

Dr. Smith's ECG Blog

JULY 21, 2024

There is no definite evidence of acute ischemia. (ie, Simply stated — t he patient was having recurrent PMVT without Q Tc prolongation, and without evidence of ongoing transmural ischemia. ( If there had been ECG findings indicating reocclusion of the artery — an angiogram would have been warranted ).

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Dr. Paddy Barrett

AUGUST 1, 2023

CT coronary angiography, in addition to a CT CAC, is arguably the best test for estimating whether someone has evidence of coronary artery disease and what that means for their near-term risk of a heart attack. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes. N Engl J Med.

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DAIC

MARCH 3, 2025

25, 2025 GE HealthCare has delivered the first patient doses of Flyrcado(flurpiridaz F 18) injection, a unit dose positron emission tomography myocardial perfusion imaging (PET MPI) agent for detecting coronary artery disease (CAD), at early adopter imaging centers in the US. tim.hodson Mon, 03/03/2025 - 16:07 Feb.

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Dr. Smith's ECG Blog

NOVEMBER 4, 2022

His response: “subendocardial ischemia. Smith : It should be noted that, in subendocardial ischemia, in contrast to OMI, absence of wall motion abnormality is common. With the history of Afib, CTA abdomen was ordered to r/o mesenteric ischemia vs ischemic colitis vs small bowel obstruction. Anything more on history?

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Dr. Smith's ECG Blog

NOVEMBER 15, 2023

Angiogram No obstructive epicardial coronary artery disease Cannot exclude non-ACS causes of troponin elevation including coronary vasospasm, stress cardiomyopathy, microvascular disease, etc. Detailed coronary artery evaluation not performed. This suggests further severe ischemia.

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Coronary Angiogram Plaque Thrombosis STEMI 110

Dr. S. Venkatesan MD

OCTOBER 29, 2024

Aggressive lipid-lowering therapy compared with angioplasty in stable coronary artery disease. Reference Pitt B, Waters D, Brown WV, van Boven AJ, Schwartz L, Title LM, Eisenberg D, Shurzinske L, McCormick LS. Atorvastatin versus Revascularization Treatment Investigators. N Engl J Med. 1999 Jul 8;341(2):70-6. PMID: 10395630.

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