Coronary Artery Disease Genetic predisposition Hypertension 
MIBHS
FEBRUARY 28, 2025
Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. A family history of heart disease often indicates that genetic factors might be at play. Can You Prevent Heart Disease if Its in Your Genes?
Frontiers in Cardiovascular Medicine
JULY 21, 2024
BackgroundThis Mendelian randomization (MR) study aimed to explore the causal relationship between the genetic predisposition to type 2 diabetes mellitus (T2DM) and aortic dissection (AD), and to assess associations with genetically predicted glycemic traits.
Frontiers in Cardiovascular Medicine
APRIL 29, 2024
However, the influence of ICP on cardiovascular disease (CVD), including hypertension (HTN) and coronary artery disease (CAD), has not been thoroughly investigated.MethodsThis study explores the causal relationship between ICP and CVD (HTN, CAD) using Mendelian Randomization (MR). 4% of pregnancies.
Circulation: Genomic and Precision Medicine
NOVEMBER 29, 2024
Although mediation analysis demonstrated that the association between PGSMDand CVDs in females was partly mediated by baseline body mass index, hypercholesterolemia, hypertension, and smoking, these risk factors did not explain the higher risk compared with males.
Physiologically Speaking
DECEMBER 17, 2024
Coronary artery calcium (CAC) is a measure of atherosclerosis and a strong predictor of cardiovascular disease. All athletes—regardless of predisposition to heart disease—should be prudent in following a generally healthy lifestyle. Family history of CAD was the most potent predictor of severe CAC.
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