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Genetic predisposition to type 2 diabetes mellitus and aortic dissection: a Mendelian randomisation study

Frontiers in Cardiovascular Medicine

JULY 21, 2024

BackgroundThis Mendelian randomization (MR) study aimed to explore the causal relationship between the genetic predisposition to type 2 diabetes mellitus (T2DM) and aortic dissection (AD), and to assess associations with genetically predicted glycemic traits.

Genetic predisposition 59
Genetic predisposition Diabetes Aortic Coronary Artery Disease 59
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Genetically predicted lipids mediate the association between intrahepatic cholestasis of pregnancy and cardiovascular disease

Frontiers in Cardiovascular Medicine

APRIL 29, 2024

However, the influence of ICP on cardiovascular disease (CVD), including hypertension (HTN) and coronary artery disease (CAD), has not been thoroughly investigated.MethodsThis study explores the causal relationship between ICP and CVD (HTN, CAD) using Mendelian Randomization (MR). 4% of pregnancies.

Cardiovascular Disease 52
Cardiovascular Disease Genetic predisposition Coronary Artery Disease Hypertension 52
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