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The optimal surveillance strategy after percutaneous coronary intervention (PCI) for high-risk patients with multivessel or left main coronaryarterydisease (CAD) remains uncertain. For more cardiology research news join our newsletter or follow us on Twitter , Facebook , LinkedIn or Instagram. J Am Coll Cardiol.
Ruff, MD, MPH, senior investigator of TIMI Group and director GeneralCardiology, Cardiovascular Division, Brigham and Women's Hospital. Patient Demographics: Patients on APT had a higher rate of coronaryarterydisease (70% vs. 42%), previous heart attacks (36% vs. 16%), and peripheral arterydisease (15% vs. 11%).
Coronaryarterydisease remains a leading cause of morbidity and mortality worldwide. Recent research has illuminated the role of total coronary atherosclerotic plaque activity across the entire coronaryarterial tree in predicting patient-level clinical outcomes.
Left main coronaryarterydisease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. However, the comparative long-term efficacy of percutaneous coronary intervention (PCI) versus coronaryartery bypass grafting (CABG) in patients with these conditions remains unclear.
The optimal management of concomitant chronic obstructive coronaryarterydisease (CAD) in transcatheter aortic valve replacement (TAVR) recipients remains a debated topic. While some advocate for pre-TAVR percutaneous coronary intervention, others adopt an expectant approach.
This highlights the need for serial ECGs in acute coronary syndrome as initial ECGs may be near normal even in those with severe disease. Classical electrocardiographic pattern in left main coronaryarterydisease is ST elevation in aVR with extensive ST depression in other leads, most prominent in I, II and V4-V6.
Microvascular resistance evaluated whether the vasodilatory reserve capacity of coronary microcirculation was restored in the infarcted territory, regardless of concomitant epicardial coronaryarterydisease and aortic pressure. Transit time is measured by saline bolus injection using a thermodilution technique.
Similar results were noted for both coronaryarterydisease and ischemic stroke. It was seen that protection associated with stair climbing was attenuated by increasing levels of disease susceptibility like family history and 10 year risk. Median follow up period was 12.5
FAME study showed that at one year follow up, rate of major adverse coronary events was reduced by approximately 30% by routinely measuring FFR. FAME 2 study randomized 1220 patients with stable coronaryarterydisease and angiographically significant stenoses in whom at least one stenosis had FFR 0.8 Cut off FFR was 0.8
As Gardner-Skinner Protocol is more popular in the evaluation of peripheral arterialdisease, in addition to the routine monitoring like ECG, heart rate and blood pressure, foot transcutaneous oxygen tension (SPO2), ankle systolic pressure and ankle/brachial systolic pressure ratio (ABI) are also checked [1].
The results advocate for considering PCI as a treatment option for such plaques, potentially expanding the indications for PCI in coronaryarterydisease management. Although there were two CSR embolisation events, no acute coronary syndrome events or deaths occurred in either group.
Relative contraindications for HUTT include: Severe left ventricular outflow obstruction Critical mitral stenosis Severe proximal coronaryarterydisease Severe cerebrovascular disease
These are useful in suspected myocardial diseases like cardiomyopathy and myocarditis. When there is a suspicion of coronaryarterydisease, exercise ECG and exercise stress echocardiography have been suggested. Nuclear cardiology imaging, cardiac computed tomography and CMR may be needed in selected cases.
Overall, it appears that rhythm control strategy in AF may be better in those with heart failure and in those with associated cardiovascular conditions and early AF.
The highly impactful International Study of Comparative Health Effectiveness With Medical and Invasive Approaches ( ISCHEMIA ) trial investigated the effectiveness of invasive (INV) versus conservative (CON) strategies for managing stable coronaryarterydisease. Original article: Gaudino M et al. EuroIntervention.
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