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Objective To explore trends in prognosis and use of glucose-lowering drugs (GLD) in patients with diabetes and coronaryarterydisease (CAD). Information on GLD (dispended 6 months before or after coronary angiography) was collected from the Swedish Prescribed Drug Registry.
Since limb events are major drivers of morbidity in diabetic patients with peripheral (PAD) and coronaryarterydisease (CAD), does the addition of ticagrelor to background therapy of aspirin improve limb events?
The outcomes of percutaneous coronary intervention (PCI) in diabetic patients are still suboptimal, and it is unclear if diabetic patients might derive a benefit from the use of drug-coated balloons.
The role of triglyceride-glucose (TyG) index, an insulin resistance indicator, in glycemic management for diabetic patients with coronaryarterydisease (CAD) was still unknown. Therefore, we aimed to explore.
However, the long-term outcomes in patient with an intermediate stenosis received FFR have not yet been investigated comprehensively.Methods:We retrospective included 558 patients underwent both coronaryartery angiography (CAG) and FFR. Circulation, Volume 150, Issue Suppl_1 , Page A4144277-A4144277, November 12, 2024.
Background:Clinical trials have demonstrated that sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP1RA) reduce cardiovascular (CV) risk in patients (pts) with type 2 diabetes (T2D) with or at high risk for CV disease.
Brittany Weber, MD, PhD , of Brigham and Women’s Hospital, is the 2024 YIA winner for her abstract, "The Frequency, Prevalence, And Outcomes Of Incidentally Detected CoronaryArtery Calcium Using Artificial Intelligence Analysis Among Patients With Immune Mediated Inflammatory Diseases.”
Background There is increasing awareness that patients without standard modifiable risk factors (SMuRFs; diabetes, hypercholesterolaemia, hypertension and smoking) may represent a unique subset of patients with acute coronary syndrome (ACS). Patients with coronaryarterydisease were excluded.
Objective To investigate the impact of prior coronaryartery bypass grafting (CABG) and coronary lesion complexity on transcatheter aortic valve replacement (TAVR) outcomes for aortic stenosis. 23), which was not associated with better/worse clinical outcomes in patients with prior CABG.
The international ARISE-HF trial was designed to test the effectiveness of the investigational drug AT-001 at stabilizing exercise capacity in patients with diabetic cardiomyopathy. Patients had had Type 2 diabetes for an average of 14 years. Decline in exercise ability is a hallmark of progression to overt heart failure.
IntroductionThere is a higher prevalence of diabetes mellitus type 2 in Hispanics as compared to other ethnic groups in the United States. Diabetes is a risk factor for acute ischemic stroke and also a poor predictor of outcome for many interventional surgeries. or greater. vs. 20.5%; p = 0.048) and stenting (28.4%
P=0.006), especially in diabetic patients (Pearsonr=0.58,P<0.001). After multivariate adjustment, every 0.1mmol/L increase in timeaveraged sdLDLC conferred a 1.2fold increased risk of PP.ConclusionsOur findings suggest that sdLDLC is an independent risk factor of PP in patients with coronaryarterydisease.
Introduction The use of contemporary drug-eluting stents (DES) has significantly improved outcomes of patients with coronaryarterydisease (CAD) undergoing percutaneous coronary intervention (PCI). years, Diabetes mellitus 29%, acute coronary syndrome 67%, chronic total occlusion 9%).
Malnutrition is common in stroke patients and leads to worse outcomes. Body mass index (BMI) is a widely available marker of nutrition status, however studies on BMI and post-ICH outcomes are limited and have conflicting results. There was no association between BMI and ICH volume in patients with deep or lobar hemorrhage.
Background and Purpose:Whether imaging markers of cerebral small vessel disease on computed tomography (CT-CSVD) relates to early clinical outcomes after intravenous thrombolysis for acute ischemic stroke remains not well understood. 1.02; score 2: OR 0.46, 95%CI 0.26-0.83; 0.83; score 3: OR 0.16, 95%CI 0.03-0.76, 1.95, p = 0.019).Conclusion:This
Migraine with aura(MwA) is associated with an increased risk of stroke and adverse vascular outcomes compared to those with migraine without aura (MwoA). Patients with any adverse vascular outcomes before the index ECG were excluded. The prevalences of all vascular outcomes are summarized in Table 1. p < 001).
BackgroundCoronary artery bypass grafting (CABG) surgery has been a widely accepted method for treating coronaryarterydisease. However, its postoperative complications can have a significant effect on long-term patient outcomes.
We present the cumulative percutaneous coronary intervention (PCI) data of all comers (stable angina and acute coronary syndromes [ACS]) who presented to Hadi Clinic between January 2018 and December 2020. A total of 567 patients underwent coronary catheterisation for the three-year period between January 2018 and December 2020.
Myocardial infarction (MI) with non-obstructive coronaryarteries (MINOCA) covers an expanding group of patients over recent years. Previous studies showed considerable risks of outcomes in this group. In this study, we aimed to investigate the long-term outcomes in very young patients with MINOCA.
Studies have reported racial disparities in young stroke patients and less desired outcomes of minorities. Socioeconomic status, risk factors, stroke etiology, acute interventions and short-term outcomes were accessed. Compared to White, black and Hispanic had higher rate of Diabetes, Hypertension and prior stroke (p<0.001).
At baseline, prevalence of comorbidities was high (hypertension 66% and 84%, hyperlipidemia 53% and 75%, coronaryarterydisease 18% and 31%, diabetes 25% and 38% in MarketScan and CDM, respectively). Introduction:Patients suffering from transient ischemic attack (TIA) are at high risk of ischemic stroke (IS).
diabetes, hypertension, coronaryarterydisease), underlying the development of cardiac dysfunction and further increased risk. Overall, understanding and utilizing NT-proBNP levels will lead to earlier and more accurate diagnoses of heart failure ultimately improving patient outcomes and reducing healthcare costs.
An elevated Lp(a) is a common genetic factor that is independently and causally related to premature coronaryarterydisease. The occurrence of disease in this instance is probabilistic, not deterministic. An elevated Lp(a) does increase the risk of early cardiovascular disease, but that risk is not set in stone.
We compared demographics, hospital traits, comorbidities, and outcomes. In-hospital mortality, our primary outcome, was analyzed through multivariate logistic regression using STATA 18.Results:Incorporating to 2.26) and liver disease (OR 2.20, p < 0.01, CI 1.27
A prior history of the following comorbidities was considered: episodic or persistent atrial fibrillation ( n = 920), coronaryarterydisease ( n = 3732), diabetes ( n = 2171), and hypertension ( n = 3353). Patients were classified into three groups based on the number of comorbidities: 0, 1–2, or ≥3.
A 56 year old male with a history of diabetes, dyslipidemia, hypertension, and coronaryarterydisease presented to the emergency department with sudden onset weakness, fatigue, lethargy, and confusion. This is another case sent by the undergraduate (who is applying to med school) who works as an EKG tech.
SPRINT originally randomized 9,361 hypertensive individuals without diabetes into two groups: intensive treatment (SBP<120 mmHg, n=4,678) and standard treatment (SBP<140 mmHg, n=4,683). We selected participants meeting SPRINTs criteria and used a validated polygenic risk score for SBP to emulate treatment effects.
Blood Sugar Management: For individuals with or at risk of diabetes, precision nutrition offers tailored strategies to manage blood glucose levels by identifying individual responses to different foods. This is particularly beneficial in managing conditions like hypertension, where precise control of dietary sodium intake is crucial.
He denied any known medical history, specifically: coronaryarterydisease, hypertension, dyslipidemia, diabetes, heart failure, myocardial infarction, or any prior PCI/stent. Vital signs were noted to be unremarkable with respect to any hypo-hypertensive crisis, hypoxia, etc. Breath sounds were clear in all lung fields.
Case submitted and written by Mazen El-Baba MD, with edits from Jesse McLaren and edits/comments by Smith and Grauer A 90-year old with a past medical history of atrial fibrillation, type-2 diabetes, hypertension, dyslipidemia, presented with acute onset chest/epigastric pain, nausea, and vomiting. Incidence of an acute coronary occlusion.
Left main coronaryarterydisease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. Preliminary evidence from trials focusing on patients with multivessel disease has hinted at diabetes as a potential modifier of treatment outcomes.
A common feedback I get is that people with existing coronaryarterydisease feel like it doesn’t apply to them. Arguably, applying the principles of prevention offers more bang for buck in the short term for people WITH coronaryarterydisease than those without coronaryarterydisease.
The patient was in his 50s with history of hypertension, diabetes, seizure disorder, and smoking, but no known coronaryarterydisease. Angiographic and clinical outcomes among patients with acute coronary syndromes presenting with isolated anterior ST-segment depressions. mm for women, 2.0 Pride et al.
Stone, MD Mount Sinai Health System tim.hodson Wed, 04/02/2025 - 15:26 March 31, 2025 Using intravascular imaging (IVI) to guide stent implantation during complex stenting procedures is safer and more effective for patients with severely calcified coronaryarterydisease than conventional angiography, the more commonly used technique.
Coronaryarterydisease is caused by the retention of a cholesterol particle in the artery wall. On the far end of that line is type two diabetes. On the far end of that line is type two diabetes. We also know that WHEN you get type 2 diabetes makes a huge difference. Let me be 100% clear, however.
BACKGROUND:Diabetes may be associated with differential outcomes in patients undergoing left main coronary revascularization with percutaneous coronary intervention (PCI) or coronaryartery bypass grafting (CABG). Patients were categorized by diabetes status. PintHR=0.87) diabetes.
Raising awareness and taking proactive steps can ensure the best possible outcomes for those at risk of heart-related conditions. Seeking emergency medical attention can restore blood flow and prevent further damage. Without immediate intervention, sudden cardiac death can occur within minutes.
A family history of heart disease often indicates that genetic factors might be at play. Common Heart Diseases with Genetic Links CoronaryArteryDisease (CAD): CAD occurs when the arteries supplying blood to the heart become narrowed or blocked.
Inflammation is a key driver of heart disease, specifically coronaryarterydisease. I have covered this topic previously here , but it is clear that inflammation plays a major role in the initiation and progression of coronaryarterydisease, and the inflammatory biomarker hsCRP is tightly connected to this process.
Background: Gender-specific outcomes after percutaneous coronary interventions were studied by a number of research groups with different endpoints and cohorts of different ethnic extractions. Results: Overall, in the unmatched cohorts, accumulated target-lesion revascularization rates did not differ between both genders (2.7%
Introduction The presence of non-coronary atherosclerosis (NCA) in patients with coronaryarterydisease is associated with a poor prognosis. We have studied whether NCA is also a predictor of poorer outcomes in patients undergoing coronaryartery bypass grafting (CABG). vs. 9%, p < 0.001).
Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 1,2 ASCVD causes or contributes to conditions that include coronaryarterydisease (CAD), cerebrovascular disease, and peripheral vascular disease (inclusive of aortic aneurysm).3
Smith Center for Outcomes Research in Cardiology and section chief of Interventional Cardiology at BIDMC. Even with advances in stent technology, patients with coronary in-stent restenosis continue to comprise approximately 10 percent of individuals undergoing angioplasty interventions each year. and Susan F.
A new joint guideline from the American Heart Association (AHA), the American College of Cardiology (ACC) and nine other medical societies reports early diagnosis and treatment of peripheral arterydisease is essential to improve outcomes and reduce amputation risk, heart attack, stroke and death for people with Peripheral ArteryDisease (PAD).
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