Journal of Cardiovascular Pharmacology

MAY 20, 2024

Our objective was to assess whether metformin could mitigate statin-induced adverse effects on PCSK9, thereby improving lipid profiles in patients with coronary artery disease (CAD) but without diabetes. Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.

Coronary Artery Disease 40

Coronary Artery Disease Diabetes Cholesterol 40

Cardiovascular Diabetology

JANUARY 5, 2024

The role of triglyceride-glucose (TyG) index, an insulin resistance indicator, in glycemic management for diabetic patients with coronary artery disease (CAD) was still unknown. Therefore, we aimed to explore.

Coronary Artery Disease 40

Coronary Artery Disease Diabetes Outcomes Research 40

Cardiology Update

MARCH 25, 2024

Left main coronary artery disease (CAD) and diabetes pose significant challenges in cardiovascular care, often leading to adverse outcomes. Preliminary evidence from trials focusing on patients with multivessel disease has hinted at diabetes as a potential modifier of treatment outcomes.

Diabetes 122

Diabetes Coronary Artery Bypass Graft Outcomes Coronary Artery Disease 122

American College of Cardiology

APRIL 26, 2024

Since limb events are major drivers of morbidity in diabetic patients with peripheral (PAD) and coronary artery disease (CAD), does the addition of ticagrelor to background therapy of aspirin improve limb events?

Diabetes 69

Diabetes Coronary Artery Disease Outcomes Article 69

Cardiovascular Diabetology

FEBRUARY 2, 2024

The outcomes of percutaneous coronary intervention (PCI) in diabetic patients are still suboptimal, and it is unclear if diabetic patients might derive a benefit from the use of drug-coated balloons.

Coronary Artery Disease 52

Coronary Artery Disease Diabetes Outcomes Research 52

Frontiers in Cardiovascular Medicine

FEBRUARY 20, 2024

We investigated whether treatment with LDE-paclitaxel changes plaque progression by coronary CT angiography and is safe in patients with chronic coronary artery disease. Analysis of inflammatory biomarkers and coronary CTA was also performed at baseline and 4 weeks after treatment.

Coronary Artery Disease 59

Coronary Artery Disease Laboratory Plaque Biomarkers 59

Frontiers in Cardiovascular Medicine

FEBRUARY 7, 2024

Background In this study, we aim to investigate the relationship between the attenuation of peri-coronary adipose tissue (PCAT) in patients with suspected coronary artery disease (CAD) and the assessment of coronary vascular functions using coronary flow reserve (CFR).

Coronary Artery Disease 64

Coronary Artery Disease Atherosclerosis Plaque Risk Factors 64

Cardiovascular Diabetology

OCTOBER 8, 2024

had a higher risk of coronary artery disease (CAD) compared to those with HbA1c 7.0–7.9%. In the ACCORD study, participants with the haptoglobin (Hp) 2–2 phenotype and glycated hemoglobin (HbA1c) ≥ 8.0% However,

Coronary Artery Disease 52

Coronary Artery Disease Diabetes Research 52

Cardiovascular Diabetology

AUGUST 27, 2024

Objective We aimed to summarize the association between gestational diabetes mellitus (GDM) and its intergenerational cardiovascular diseases (CVDs) impacts in both mothers and offspring post-delivery in existing literature.

Cardiovascular Disease 85

Cardiovascular Disease Diabetes Cerebrovascular Disease Coronary Artery Disease 85

Frontiers in Cardiovascular Medicine

JULY 21, 2024

BackgroundThis Mendelian randomization (MR) study aimed to explore the causal relationship between the genetic predisposition to type 2 diabetes mellitus (T2DM) and aortic dissection (AD), and to assess associations with genetically predicted glycemic traits. The findings remained stable across various MR models and sensitivity analyses.

Genetic predisposition 59

Genetic predisposition Diabetes Aortic Coronary Artery Disease 59

Circulation

MARCH 11, 2024

Patients were categorized by diabetes status. Kaplan-Meier event rates, Cox model hazard ratios, and interactions were assessed.RESULTS:Among 4393 patients, 1104 (25.1%) had diabetes. PintHR=0.87) diabetes. Patients were considered suitable for either approach. and 9.9%) compared with those without (2.1%

Coronary Artery Bypass Graft 81

Coronary Artery Bypass Graft Diabetes Coronary Artery Disease Stents 81

American Heart News - Heart News

JANUARY 16, 2024

Research shows that chronic gum inflammation may be associated with other chronic diseases including coronary artery disease and diabetes.[1] DALLAS, JANUARY 16, 2024 — A patient’s oral health can be an indicator of overall health and well-being.

Coronary Artery Disease 81

Coronary Artery Disease Chronic Disease Heart Disease Diabetes 81

DAIC

APRIL 9, 2024

The international ARISE-HF trial was designed to test the effectiveness of the investigational drug AT-001 at stabilizing exercise capacity in patients with diabetic cardiomyopathy. Patients had had Type 2 diabetes for an average of 14 years. Decline in exercise ability is a hallmark of progression to overt heart failure.

Heart Failure 52

Heart Failure Diabetes Cardiomyopathy Exercise 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Type 2 Diabetes Mellitus (T2DM) is a rapidly growing global health problem with increasing prevalence. Of those patients, 35.43% (n=273,993) were diabetic and 64.57% (n=151,112) were non‐diabetic. Diabetics were more likely to be younger (70.43 Among diabetics, readmitted patients were more likely to be older (71.87

Diabetes 40

Diabetes Coronary Artery Disease Atrial Fibrillation Dementia 40

The American Journal of Cardiology

JUNE 16, 2024

Publication date: Available online 15 June 2024 Source: The American Journal of Cardiology Author(s): Abdul Aziz Asbeutah, Ralph Daher, Abdulaziz Malik, Essa Hariri, Abdulhamied Alfaddagh, Tarec K. Elajami, Francine K.

Coronary Artery Disease 40

Coronary Artery Disease Diabetes 40

Dr. Paddy Barrett

APRIL 5, 2024

A common feedback I get is that people with existing coronary artery disease feel like it doesn’t apply to them. Arguably, applying the principles of prevention offers more bang for buck in the short term for people WITH coronary artery disease than those without coronary artery disease.

Heart Disease 101

Heart Disease Coronary Artery Disease Heart Attack Heart attacks 101

Open Heart

NOVEMBER 14, 2023

Previously, 80% of sudden cardiac arrest have been attributed to coronary artery disease. had type 2 diabetes, compared with 19.6% Among hospitalised patients, 30% were diagnosed with AMI, 27% with hypertension, 20% with ischaemic heart disease and 18% with heart failure as discharge diagnoses. Among women, 18.0%

Cardiac Arrest 52

Cardiac Arrest Coronary Artery Disease Hospital Heart Failure 52

Open Heart

AUGUST 25, 2024

Multivariable Cox models, adjusted for clinical and imaging variables, showed that diabetes (HR: 2.38; p=0.008), HEART score of 3 (HR: 1.32; p=0.01), history of coronary artery disease (HR: 2.75; p=0.003), ECG changes (HR: 5.11; p<0.0001) and abnormal NISI (HR: 16.4;

Chest Pain 52

Chest Pain Coronary Artery Disease Myocardial Infarction Electrocardiogram 52

Dr. Paddy Barrett

OCTOBER 4, 2024

But the goal in this instance is to die after a long and healthy life ‘ with ’ coronary artery disease rather than ‘ from ’ coronary artery disease. However, the chances of dying from heart disease are directly proportional to the amount of plaque in your coronary arteries.

Heart Disease 72

Heart Disease Plaque Cholesterol Risk Factors 72

Frontiers in Cardiovascular Medicine

DECEMBER 13, 2023

Cancer, atrial fibrillation (AF) and coronary artery disease share some common factors and interact with each other, such as obesity, aging, diabetes, and inflammation, but the potential specific mechanism is still unclear. A growing number of studies have elucidated the association between cancer and CVD.

Atrial Fibrillation 64

Atrial Fibrillation Cancer Embolism Coronary Artery Disease 64

Coronary Artery Disease Journal

NOVEMBER 20, 2023

Data were pooled and analyzed in terms of clinical outcomes to assess the impact of gender in patients with stable coronary artery disease and acute coronary syndrome. After propensity-score-matching, primarily adjusting for age, hypertension and diabetes, our data revealed similar accumulated MACE in women and men (5.5%

Stent 52

Stent Stents Outcomes Coronary Artery Disease 52

Coronary Artery Disease Journal

MAY 13, 2024

Objective To investigate the impact of prior coronary artery bypass grafting (CABG) and coronary lesion complexity on transcatheter aortic valve replacement (TAVR) outcomes for aortic stenosis. The impact of the CABG SYNTAX score was also evaluated in patients with prior CABG.

Coronary Artery Bypass Graft 40

Coronary Artery Bypass Graft Aortic valve Aortic Stenosis 40

DAIC

JULY 23, 2024

Haechan Cho, MD received Best Abstract first runner-up after presenting his abstract, “Coronary Computed Tomography Angiography Versus Functional Testing In Patients With Diabetes And Suspected Coronary Artery Disease: Real-world Evidence From The Nationwide Cohort.”

Coronary Artery Disease 105

Coronary Artery Disease Chest Pain Plaque Ischemia 105

Dr. Paddy Barrett

OCTOBER 11, 2024

Inflammation is a key driver of heart disease, specifically coronary artery disease. I have covered this topic previously here , but it is clear that inflammation plays a major role in the initiation and progression of coronary artery disease, and the inflammatory biomarker hsCRP is tightly connected to this process.

Obesity 52

Obesity Dementia Cancer Coronary Artery Disease 52

Frontiers in Cardiovascular Medicine

FEBRUARY 23, 2024

Introduction The presence of non-coronary atherosclerosis (NCA) in patients with coronary artery disease is associated with a poor prognosis. We have studied whether NCA is also a predictor of poorer outcomes in patients undergoing coronary artery bypass grafting (CABG). 2.69], age (HR = 1.35, 95% CI 1.09–1.67,

Coronary Artery Bypass Graft 64

Coronary Artery Bypass Graft Atherosclerosis Peripheral Arterial Disease Coronary Artery Disease 64

Open Heart

JUNE 5, 2024

Background There is increasing awareness that patients without standard modifiable risk factors (SMuRFs; diabetes, hypercholesterolaemia, hypertension and smoking) may represent a unique subset of patients with acute coronary syndrome (ACS). Patients with coronary artery disease were excluded.

Cardiogenic Shock 52

Cardiogenic Shock Myocardial Infarction Outcomes Coronary Artery Disease 52

Dr. Paddy Barrett

JUNE 21, 2024

The same is true of uncontrolled diabetes or high blood pressure. What I am trying to get across is that it is very common for a parent to have had heart disease, but that does not mean it has a genetic origin. Most of the time, coronary artery disease will be the cause. But not always. What To Look For Ok.

Heart Disease 64

Heart Disease Heart Attack Heart attacks Coronary Artery Disease 64

Dr. Paddy Barrett

MAY 20, 2024

Every day we learn something new about the complexity of coronary artery disease. But we have known for decades that getting these core factors right substantially reduces your risk of heart disease. Avoiding diabetes. This is a huge difference. Being physically active. Not smoking. Having good nutrition.

Coronary Artery Disease 69

Coronary Artery Disease Heart Disease Blood Pressure Cholesterol 69

Hypertension Journal

DECEMBER 11, 2023

This study investigated the long-term risk of cardiovascular disease events in individuals with home SBP &lt;125 versus 125 to &lt;135 or ≥135 mm Hg who participated in the J-HOP study (Japan Morning Surge-Home Blood Pressure).METHODS:The 2.00] for overall cardiovascular disease and 2.68 [95% CI, 1.34–5.38]

Blood Pressure 40

Blood Pressure Coronary Artery Disease Cardiovascular Disease Heart Failure 40

DAIC

MARCH 6, 2024

milla1cf Wed, 03/06/2024 - 18:48 March 6, 2024 — Cleerly , the company on a mission to create a new standard of care to aid in the diagnosis of heart disease, has been granted Breakthrough Device Designation by the U.S. Food and Drug Administration ( FDA ) for its Coronary Artery Disease ( CAD ) Staging System.

Heart Disease 105

Heart Disease Heart Attack Heart attacks Technology 105

Frontiers in Cardiovascular Medicine

JANUARY 7, 2024

Introduction The use of contemporary drug-eluting stents (DES) has significantly improved outcomes of patients with coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI). years, Diabetes mellitus 29%, acute coronary syndrome 67%, chronic total occlusion 9%). Of these, 40.9%

Stent 64

Stent Stents Cardiogenic Shock Coronary Artery Disease 64

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionThere is a higher prevalence of diabetes mellitus type 2 in Hispanics as compared to other ethnic groups in the United States. Diabetes is a risk factor for acute ischemic stroke and also a poor predictor of outcome for many interventional surgeries. or greater. vs. 20.5%; p = 0.048) and stenting (28.4%

Outcomes 40

Outcomes Angioplasty Atrial Fibrillation Diabetes 40

Dr. Paddy Barrett

SEPTEMBER 13, 2024

Insulin resistance is a major risk factor for the leading causes of death, the leading one being cardiovascular disease. Everyone sits somewhere on the scale of insulin sensitivity from very insulin sensitive to very insulin resistant at the point of type 2 diabetes. Measuring Insulin Resistance. Some complex. Some simple.

Risk Factors 90

Risk Factors Heart Disease Dementia Diabetes 90

Stroke Journal

FEBRUARY 1, 2024

Compared to White, black and Hispanic had higher rate of Diabetes, Hypertension and prior stroke (p&lt;0.001). The rates of other risk factors (hyperlipidemia, smoking, illicit drug use, chronic heart failure, coronary artery disease, and atrial fibrillation) did not vary by race.

Stroke 40

Stroke Strokes Coronary Artery Disease Risk Factors 40

Dr. Paddy Barrett

SEPTEMBER 20, 2024

For every one standard deviation increase of ApoB, the risk of coronary artery disease increases by 65% 2. Except in the setting of type 2 diabetes, metabolic syndrome, insulin resistance and obesity. 2 Dose-Response Associations of Lipid Traits With Coronary Artery Disease and Mortality.

Heart Disease 99

Heart Disease Cholesterol Atherosclerosis Heart Attack 99

European Journal of Heart Failure

SEPTEMBER 26, 2023

diabetes, hypertension, coronary artery disease), underlying the development of cardiac dysfunction and further increased risk. Validated cut-points are provided to rule in or rule out acute heart failure in the emergency department and to diagnose de novo heart failure in the outpatient setting.

Heart Failure 40

Heart Failure Coronary Artery Disease Outpatient Document 40

AMS Cardiology

SEPTEMBER 30, 2024

Regular heart check-ups offer several benefits including: Early detection of heart disease : Many heart conditions such as high blood pressure, high cholesterol and coronary artery disease can be detected early through regular screenings.

Heart Disease 52

Heart Disease Blood Pressure Cholesterol Risk Factors 52