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The role of physiology in the contemporary management of coronary artery disease

Heart BMJ

Coronary physiology assessment, including epicardial and microvascular investigations, is a fundamental tool in the contemporary management of patients with coronary artery disease. Coronary revascularisation guided by functional evaluation has demonstrated superiority over angiography-only-guided treatment.

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Systematic coronary physiology improves level of agreement in diagnostic coronary angiography

Open Heart

Objective The training of interventional cardiologists (ICs), non-interventional cardiologists (NICs) and cardiac surgeons (CSs) differs, and this may be reflected in their interpretation of invasive coronary angiography (ICA) and management plan. Trial registration number NCT01070771.

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Diffuse Subendocardial Ischemia on the ECG. Left main? 3-vessel disease? No!

Dr. Smith's ECG Blog

Author continued : STE in aVR is often due to left main coronary artery obstruction (OR 4.72), and is associated with in-hospital cardiovascular mortality (OR 5.58). Any alteration in physiology can change "compensated" AS to "decompensated" AS. 2 The astute paramedic recognized this possibility and announced a CODE STEMI.

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Unraveling the Link Between Mental Health and Cardiovascular Disease 

Cardiometabolic Health Congress

Other studies have also unearthed more intricate connections which suggests that physiological conditions, underpinned by biological and chemical factors, may also play a pivotal role in influencing cardiovascular disease (CVD). Indeed, several studies have reported higher rates of depression among people with CVD.

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Abstract 4141170: Impact of Serum 5-Hydroxytryptophan Levels on 15-Year Major Adverse Cardiovascular Events in ST-Elevation Myocardial Infarction Patients

Circulation

Background:5-Hydroxytryptophan (5-HTP) is a natural amino acid and precursor to serotonin, which is essential for various physiological functions. Circulation, Volume 150, Issue Suppl_1 , Page A4141170-A4141170, November 12, 2024.

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Myocardial revascularisation in complex patients: does it happen as prescribed by the heart team?

The British Journal of Cardiology

The clinical questions were coronary artery bypass graft (CABG) versus percutaneous coronary intervention (PCI) (141 cases, 91%), and medical treatment versus revascularisation by PCI (eight cases, 6%) or by CABG (five cases, 3%). We identified 154 patients (117 male), mean age 68.9 ± 11.4