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Atrial Fibrillation Ablation in Congenital Heart Disease: Therapeutic Challenges and Future Perspectives

Journal of the American Heart Association

The increasing prevalence of atrial fibrillation (AF) in adults with congenital heart disease raises significant questions regarding its management. The unique underlying anatomic and physiological background further adds to the difficulty in eliminating the AF burden in these patients.

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Congenital Heart Defects: Helping Families Navigate the Challenges

MIBHS

Congenital heart defects (CHDs) are the most common type of birth defect, affecting nearly 1 in 100 newborns. Understanding Congenital Heart Defects A congenital heart defect refers to a problem with the structure of the heart that is present at birth. These structural abnormalities of the heart are present at birth.

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Neurodevelopmental Outcomes for Individuals With Congenital Heart Disease: Updates in Neuroprotection, Risk-Stratification, Evaluation, and Management: A Scientific Statement From the American Heart Association

Circulation

Over the past decade, new research has advanced scientific knowledge of neurodevelopmental trajectories, factors that increase neurodevelopmental risk, and neuroprotective strategies for individuals with congenital heart disease.

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The mechanics of congenital heart disease: from a morphological trait to the functional echocardiographic evaluation

Frontiers in Cardiovascular Medicine

Advances in pediatric cardiac surgery have resulted in a recent growing epidemic of children and young adults with congenital heart diseases (CHDs). In these patients, congenital defects themselves, surgical operations and remaining lesions may alter cardiac anatomy and impact the mechanical performance of both ventricles.

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Time to childbirth and assisted reproductive treatment in women with congenital heart disease

Open Heart

Objective To investigate the time to first childbirth and to compare the prevalence of assisted reproductive treatment (ART) in women with congenital heart disease (CHD) compared with women without CHD. Age was an important risk factor for ART also in women with CHD and should be considered in consultations with these patients.

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Maternal Type 1 Diabetes Increases Congenital Heart Defect Risk in Children

HCPLive

A new study identified T1D as a risk factor associated with nearly all subtypes of CHD, whereas overweight was associated only with certain defect types.

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Abstract 4147910: 22q11 Deletion Syndrome: A Potenitial Risk Factor For Left Pulmonary Artery Hypoplasia and Need For Intervention in Patients With Congeital Heart Disease

Circulation

Animal studies have shown that mice with TBX1 gene mutations have smaller left pulmonary arteries compared to wild type mice, defined by a reduced left pulmonary artery (LPA) to right pulmonary artery (RPA) ratio. A single study has shown this translates to humans with 22q11 and structurally normal hearts.