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Atrial Fibrillation Ablation in Congenital Heart Disease: Therapeutic Challenges and Future Perspectives

Journal of the American Heart Association

The increasing prevalence of atrial fibrillation (AF) in adults with congenital heart disease raises significant questions regarding its management. The unique underlying anatomic and physiological background further adds to the difficulty in eliminating the AF burden in these patients.

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Neurodevelopmental Outcomes for Individuals With Congenital Heart Disease: Updates in Neuroprotection, Risk-Stratification, Evaluation, and Management: A Scientific Statement From the American Heart Association

Circulation

Over the past decade, new research has advanced scientific knowledge of neurodevelopmental trajectories, factors that increase neurodevelopmental risk, and neuroprotective strategies for individuals with congenital heart disease.

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Time to childbirth and assisted reproductive treatment in women with congenital heart disease

Open Heart

Objective To investigate the time to first childbirth and to compare the prevalence of assisted reproductive treatment (ART) in women with congenital heart disease (CHD) compared with women without CHD. ART was more common in women with CHD, but disease severity did not influence the need for ART.

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The mechanics of congenital heart disease: from a morphological trait to the functional echocardiographic evaluation

Frontiers in Cardiovascular Medicine

Advances in pediatric cardiac surgery have resulted in a recent growing epidemic of children and young adults with congenital heart diseases (CHDs). In these patients, congenital defects themselves, surgical operations and remaining lesions may alter cardiac anatomy and impact the mechanical performance of both ventricles.

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Heart Disease and Stroke Could Affect at Least 60% of Adults in U.S. by 2050, According to American Heart Association Advisories

DAIC

A projected rise in heart disease and stroke – along with several key risk factors, including high blood pressure and obesity – is likely to triple related costs to $1.8 population could be affected by cardiovascular disease within the next 30 years, according to two new science reports. to 61% of the U.S.

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Abstract 4147910: 22q11 Deletion Syndrome: A Potenitial Risk Factor For Left Pulmonary Artery Hypoplasia and Need For Intervention in Patients With Congeital Heart Disease

Circulation

A single study has shown this translates to humans with 22q11 and structurally normal hearts. Animal studies have shown that mice with TBX1 gene mutations have smaller left pulmonary arteries compared to wild type mice, defined by a reduced left pulmonary artery (LPA) to right pulmonary artery (RPA) ratio.

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COVID-19 in congenital heart disease (COaCHeD) study

Open Heart

Congenital heart disease (CHD) is likely to increase vulnerability and understanding the predictors of adverse outcomes is key to optimising care. Objective Ascertain the impact of COVID-19 on people with CHD and define risk factors for adverse outcomes.