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Case Report: IVC-agenesis and FVL mutation; successful DVT/PE treatment with direct oral anticoagulation (factor Xa inhibitor)

Frontiers in Cardiovascular Medicine

Inferior vena cava (IVC) agenesis is a rare congenital anomaly that has been implicated in up to 5% of unprovoked deep vein thrombosis (DVT) cases in young men under 30 years old. We present the case of a 28-year-old obese Caucasian male who arrived at our hospital with significant pain and swelling in his right lower extremity.

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CircRNA-mediated regulation of cardiovascular disease

Frontiers in Cardiovascular Medicine

stroke), peripheral arterial disease, congenital heart anomalies, deep vein thrombosis, and pulmonary embolism. Cardiovascular diseases (CVDs) encompass a range of disorders affecting the heart and blood vessels, such as coronary heart disease, cerebrovascular disease (e.g.,