Remove Congenital Heart Disease Remove Pediatrics Remove Transplant
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The impact of pre-transplant ventricular assist device support in pediatric patients with end-stage heart failure on the outcomes of heart transplantation—“a single center experience”

Frontiers in Cardiovascular Medicine

IntroductionThe objective of this study was to examine the impact of ventricular assist device support as a bridge to heart transplantation in children with end-stage heart failure. Patients were divided into two groups: with pre transplant ventricular assist device (VAD) support and without VAD support.

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Overcoming the Odds with Expert Fetal Cardiology Care: Zeke and Zane’s Story

Conquering CHD

Zeke and Zane were both diagnosed with hypoplastic left heart syndrome (HLHS) before birth. As far as congenital heart diseases go, HLHS falls on the rarer end of the spectrum. The Heart Institute collaborates with the CFCC through the Fetal Cardiology Program.

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Arrhythmias in children undergoing orthotopic heart transplantation

Frontiers in Cardiovascular Medicine

Introduction Heart transplantation (HT) is the only treatment option in children with heart failure secondary to cardiomyopathies and non-reparable congenital heart diseases. We did not identify significant risk factors for arrhythmias post-HT.

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Abstract 4146466: Targeting Gut Microbiota-Derived Kynurenine to Predict and Protect the Remodeling of the Pressure Overloaded Young Heart

Circulation

Background:Without timely intervention, pressure-overloading left ventricular (poLV) remodeling may become progressive and readily degenerate into heart failure. Kyn is a pathological signal from an altered gut microbiota to activates AHR and its gene targets in poLV remodeling heart, promoting hypertrophy and fibrosis in respective cells.

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Long-Term Outcomes of Cardiac Resynchronization Therapy in Patients With Repaired Tetralogy of Fallot: A Multicenter Study

Circulation: Arrhythmia and Electrophysiology

This study aimed to investigate the early and late efficacy, survival, and safety of CRT in patients with tetralogy of Fallot.METHODS:Data were analyzed from an observational, retrospective, multicenter cohort, initiated jointly by the Pediatric and Congenital Electrophysiology Society and the International Society of Adult Congenital Heart Disease.

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Impact of Heart Transplant Allocation Changes on Waitlist Mortality and Clinical Practice in Pediatric and Adult Patients With Congenital Heart Disease and Cardiomyopathy

Circulation

BACKGROUND:The United Network of Organ Sharing made changes to the priority for allocation of hearts for transplantation (HT) in 2016 for pediatric patients and 2018 for adult patients. Circulation, Ahead of Print.

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Use of Right Ventricular Free-Wall Strain in a Multivariable Estimate of Right Ventricular-Arterial Coupling in Pediatric Pulmonary Arterial Hypertension

Circulation: Cardiovascular Imaging

Noninvasive surrogates for RVAC using echocardiographic estimates of right ventricular function, such as tricuspid annular plane systolic excursion (TAPSE), have been shown to correlate with invasively measured RVAC and predict clinical outcomes in pediatric pulmonary arterial hypertension.