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Nature Reviews Cardiology, Published online: 20 January 2025; doi:10.1038/s41569-025-01118-1 The past 20 years have witnessed remarkable progress in the evolution of transcatheter procedures for the treatment of adult patients with congenitalheartdisease.
In adults with congenitalheartdisease (ACHD patients), atrial arrhythmias (AA) and heart failure (HF) are common. 1 Factors related to congenitalheartdisease, such as underlying anatomy, surgical repair technique and scars, can all be considered as AA substrates.
Research Highlights: Almost 1 in 5 adults with congenitalheartdisease living in Israel had or developed an abnormal heart rhythm over five years. Adults with congenitalheartdisease who developed an irregular heart rhythm in the heart’s upper.
Aim To assess the effectiveness and safety of strength training (ST) interventions in people with congenitalheartdisease (ConHD). Methods Participants included people of all ages diagnosed with all complexity of ConHD.
Background Atrial arrhythmias (AA) and heart failure (HF) are major causes of hospitalisation in adult congenitalheartdisease (ACHD). Methods In this single-centre retrospective cohort study, data from 3995 patients with ACHD were analysed.
An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report. The organoids recapitulate hallmarks of pregestational diabetes-induced congenitalheartdisease found in mice and humans.
Statement Highlights: A new American Heart Association scientific statement updates more than a decade of research identifying, managing and preventing neurodevelopmental delays and disorders among people with congenitalheartdisease.
(MedPage Today) -- Among babies with severe congenitalheartdisease (CHD), neurological abnormalities tended to cluster in those who had been exposed to some placental pathology while still in the womb, a single-center prospective study found.
Background Infants with congenitalheartdisease (CHD) are clinically vulnerable to cardiac deteriorations and intercurrent infections. We aimed to quantify the impact of health system disruptions during the COVID-19 pandemic, on their clinical outcomes and whether these differed by socioeconomic and ethnic subgroups.
Scientists at the Icahn School of Medicine at Mount Sinai and collaborators have identified novel genetic interactions that may contribute to congenitalheartdisease (CHD), a common birth defect.
Background Short-term improvements in quality of life (QOL) have been reported in adult congenitalheartdisease patients with systemic right ventricle (sRV) failure after treatment with sacubitril/valsartan. This study aimed to evaluate the medium-term QOL changes in sRV failure patients treated with sacubitril/valsartan.
Our aim was to assess the impact on paediatric congenitalheartdisease (CHD) procedures during different pandemic periods compared with the prepandemic period, to inform appropriate responses to future major health services disruptions. Background The COVID-19 pandemic necessitated major reallocation of healthcare services.
The prevalence of congenitalheartdisease (CHD) in adult patients has risen with advances in diagnostic and surgical techniques. Patients with CHD commonly experience both supraventricular and ventricular arrhythmias, with each CHD type associated with different arrhythmia patterns.
Among simple congenitalheartdiseases (CHD), patent foramen ovale (PFO) is associated with a significantly higher risk for epilepsy, according to a study published in the February issue of CNS Neuroscience & Therapeutics.
Journal of the American Heart Association, Ahead of Print. Survivorship from congenitalheartdisease has improved rapidly secondary to advances in surgical and medical management. This is an updated report of the American Heart Association's previous publications on exercise in children.
Journal of the American Heart Association, Ahead of Print. The increasing prevalence of atrial fibrillation (AF) in adults with congenitalheartdisease raises significant questions regarding its management. Emerging imaging modalities and ablation techniques might have a role to play.
Objective To determine the magnitude of any excess risk of mortality and hospitalisation due to COVID-19 infection in patients with congenitalheartdisease (CHD) in the UK healthcare system.
Developments in cardiovascular (CV) surgery and related care have led to the improved survival of patients with congenitalheartdisease (CHD) and more teenagers and adults living with congenitalheartdisease (ACHD).
For adults with congenitalheartdisease (ACHD), those with heart failure (HF) hospitalizations have an increased risk for mortality and morbidity, according to a study published in the Dec. 5 issue of the Journal of the American Heart Association.
Congenitalheart defects are the most common type of birth defect, affecting 1% of live births. The underlying cause of congenitalheartdisease is frequently unknown.
addressed the safety, tolerability, and outcomes of patients with adult congenitalheartdisease (ACHD) treated with sodium-glucose cotransporter 2 inhibitors (SGLT2i). Neijenhuis et al. and Fusco et al.
February marks CongenitalHeart Defect Awareness Week, an opportunity to reflect on the remarkable advancements in the care for congenitalheartdisease (CHD). Historically viewed with a grim outlook, CHD has journeyed from a potentially lethal condition to a chronic disease managed into adulthood.
Over the past decade, new research has advanced scientific knowledge of neurodevelopmental trajectories, factors that increase neurodevelopmental risk, and neuroprotective strategies for individuals with congenitalheartdisease.
Due to improvements in recognition and management of their multisystem disease, the long‐term survival of infants, children, and adolescents with trisomy 21 and congenitalheartdisease now matches children with congenitalheartdisease and no genetic condition in many scenarios.
In this panel discussion, host Andrea Price MS, AACC brings together Tricia Keegan, NP, DNP, FACC, Disty Pearson, PA-C, AACC, and Bailey Estes MSN, AGNP-C, to explore best practices related to structural heartdisease. In this episode, the focus is on congenitalheartdisease.
The prevalence of congenitalheartdisease (CHD) is higher among those who live at higher altitudes, and more prevalent among females, according to a new study presented at ACC Latin America 2024.
The prevalence of congenitalheartdisease (CHD) in pregnancy increased by >30% during the 2010s. CHD is now present in approximately 8:10,000 pregnant persons.
6, 2025 Medtronic plc hasannounced it received CE ( Conformit Europenne ) Mark for the Harmony Transcatheter Pulmonary Valve (TPV) System, a minimally invasive alternative to open-heart surgery for congenitalheartdisease patients with native or surgically repaired right ventricular outflow tract (RVOT).
Video Pitfalls in Adult CongenitalHeartDisease for the Aortic Surgeon kchalko Sun, 12/01/2024 - 13:53 STS President Dr. Jennifer Romano presented at the 2024 STS and Asian Society for Cardiovascular and Thoracic Surgery Aortic Summit in Tokyo (November 16, 2024) on adults with congenitalheartdisease.
The following are key points to remember from an American Heart Association Scientific Statement on neurodevelopmental outcomes for individuals with congenitalheartdisease, which includes updates in neuroprotection, risk-stratification, evaluation, and management.
The global prevalence of congenitalheartdisease is higher among women who live at high altitudes, according to a new study presented at ACC Latin America 2024 in Punta Cana, Dominican Republic.
What is the impact of intraoperative His bundle (HB) mapping during complex biventricular congenitalheartdisease (CHD) repair on postoperative atrioventricular block requiring pacemaker (AVB/PM)?
BackgroundCongenital heartdisease (CHD) is a major contributor to morbidity and infant mortality and imposes the highest burden on global healthcare costs. Early diagnosis and prompt treatment of CHD contribute to enhanced neonatal outcomes and survival rates; however, there is a shortage of proficient examiners in remote regions.
LEARNING OBJECTIVES Review the diagnostic pathway for pulmonary arterial hypertension (PAH) in congenitalheartdisease (CHD). Understand and interpret right heart catheterisation data in pulmonary hypertension related to CHD. Recognise the typical presentation of PAH in patients with CHD.
A research team reported recently that heart muscle cells grown from induced pluripotent stem cells can integrate into the hearts of monkeys with a state of pressure overload.
The following are key points to remember from an American Heart Association scientific statement on the evaluation and management of chronic heart failure (HF) in children and adolescents with congenitalheartdisease (CHD).
(MedPage Today) -- A child's risk of congenitalheartdisease (CHD) may be related to a past hepatitis B virus (HBV) infection in either parent, according to a retrospective cohort study. Paternal preconception HBV infection was linked to significantly.
Congenitalheartdisease is a prevalent birth defect, accounting for approximately one-third of major birth defects. In response, we have released a dataset containing 828 DICOM chest x-ray files from children with diagnosed congenitalheartdisease, alongside corresponding cardiac ultrasound reports.
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