This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
Nature Reviews Cardiology, Published online: 20 January 2025; doi:10.1038/s41569-025-01118-1 The past 20 years have witnessed remarkable progress in the evolution of transcatheter procedures for the treatment of adult patients with congenital heart disease.
Background In congenital aortic stenosis (CAS), commissurotomy is an option in patients not suitable to receive a valve prosthesis. Materials and methods The national register on congenital heart diseases (CHDs) was searched for patients with CAS, simple or associated with other CHD and an index commissurotomy with later data from follow-up.
ObjectiveDespite advancements in surgical techniques, many patients born with congenital heart defects (CHD) require repeated reinterventions due to the limitations of materials used in congenital cardiac surgery (CCS).
In adults with congenital heart disease (ACHD patients), atrial arrhythmias (AA) and heart failure (HF) are common. 1 Factors related to congenital heart disease, such as underlying anatomy, surgical repair technique and scars, can all be considered as AA substrates.
(MedPage Today) -- A 4-month-old with congenital hyperinsulinism responded well to off-label treatment with a breast cancer drug, researchers reported. A newborn presented with severe congenital hyperinsulinism due to homozygous deletion of the.
Aim To assess the effectiveness and safety of strength training (ST) interventions in people with congenital heart disease (ConHD). Methods Participants included people of all ages diagnosed with all complexity of ConHD.
Research Highlights: Almost 1 in 5 adults with congenital heart disease living in Israel had or developed an abnormal heart rhythm over five years. Adults with congenital heart disease who developed an irregular heart rhythm in the heart’s upper.
No previous reports have documented the coexistence of congenital absence of the RCA and complete AV block in the same patient.Case summariesCase 1 was a 52-year-old man with no significant past medical history who experienced syncope. The prevalence of complete atrioventricular (AV) block also appears to be low.
Background Atrial arrhythmias (AA) and heart failure (HF) are major causes of hospitalisation in adult congenital heart disease (ACHD). This study aimed to evaluate the temporal relationship between AA and HF onset, the association between HF and the success of radiofrequency ablation (RFA), and how HF influences outcomes in patients with AA.
Crinecerfont is indicated to be used with glucocorticoids to control androgen levels in adults and pediatric patients with classic congenital adrenal hyperplasia.
History of the Congenital Heart Futures Act First passed into law in 2010, the bipartisan Congenital Heart Futures Act was groundbreaking legislation authorizing research and data collection specific to Congenital Heart Disease. Raising awareness of CHD through the lifespan.
The organoids recapitulate hallmarks of pregestational diabetes-induced congenital heart disease found in mice and humans. An advanced human heart organoid system can be used to model embryonic heart development under pregestational diabetes-like conditions, researchers report.
Statement Highlights: A new American Heart Association scientific statement updates more than a decade of research identifying, managing and preventing neurodevelopmental delays and disorders among people with congenital heart disease.
(MedPage Today) -- Among babies with severe congenital heart disease (CHD), neurological abnormalities tended to cluster in those who had been exposed to some placental pathology while still in the womb, a single-center prospective study found.
Background Infants with congenital heart disease (CHD) are clinically vulnerable to cardiac deteriorations and intercurrent infections. We aimed to quantify the impact of health system disruptions during the COVID-19 pandemic, on their clinical outcomes and whether these differed by socioeconomic and ethnic subgroups.
Scientists at the Icahn School of Medicine at Mount Sinai and collaborators have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth defect.
Our aim was to assess the impact on paediatric congenital heart disease (CHD) procedures during different pandemic periods compared with the prepandemic period, to inform appropriate responses to future major health services disruptions. Background The COVID-19 pandemic necessitated major reallocation of healthcare services.
are forms of congenital heart defects (CHD). about 12 infants in 1,000 births have a congenital heart defect, according to the Associations 2025 Heart Disease and Stroke Statistics. Researchers have yet to determine why having a baby with a congenital heart defect is associated with a higher risk for cancer in mothers.
To date, biallelic loss-of-function variants in 3 genes encoding nonredundant enzymes of the NAD de novo synthesis pathway — KYNU, HAAO, and NADSYN1 — have been identified in humans with congenital malformations defined as congenital NAD deficiency disorder (CNDD).
This rare case of a left main congenital coronary aneurysm suggests that treatment should consider the patient's overall condition, thrombosis presence, suitability for anticoagulant therapy, and aneurysm location and size. Due to the high surgical risk, conservative treatment was chosen.
Background Short-term improvements in quality of life (QOL) have been reported in adult congenital heart disease patients with systemic right ventricle (sRV) failure after treatment with sacubitril/valsartan. This study aimed to evaluate the medium-term QOL changes in sRV failure patients treated with sacubitril/valsartan.
The prevalence of congenital heart disease (CHD) in adult patients has risen with advances in diagnostic and surgical techniques. Surgical modifications and hemodynamic changes increase the susceptibility to arrhythmias, impacting morbidity and mortality rates, with arrhythmias being the leading cause of hospitalizations and sudden deaths.
Dr. Shettys team benchmarked their results with those recorded in the STS Congenital Heart Surgery Database (CHSD)which contains more than 600,000 congenital heart surgery procedure records and currently has more than 1,000 participating physicians, including surgeons and anesthesiologists.
Among simple congenital heart diseases (CHD), patent foramen ovale (PFO) is associated with a significantly higher risk for epilepsy, according to a study published in the February issue of CNS Neuroscience & Therapeutics.
For children battling both congenital heart defects (CHD) and cancer, the road to recovery is far more precarious than previously understood, according to a study published in the Journal of the National Cancer Institute.
Survivorship from congenital heart disease has improved rapidly secondary to advances in surgical and medical management. The purpose of this statement is to provide a lifespan approach to the interpretation of cardiopulmonary exercise testing in patients with congenital heart disease.
The increasing prevalence of atrial fibrillation (AF) in adults with congenital heart disease raises significant questions regarding its management. The unique underlying anatomic and physiological background further adds to the difficulty in eliminating the AF burden in these patients.
Objective To determine the magnitude of any excess risk of mortality and hospitalisation due to COVID-19 infection in patients with congenital heart disease (CHD) in the UK healthcare system.
Congenital heart defects are the most common type of birth defect, affecting 1% of live births. The underlying cause of congenital heart disease is frequently unknown. However, advances in human genetics and genome technologies have helped expand congenital heart disease pathogenesis knowledge during the last few decades.
February marks Congenital Heart Defect Awareness Week, an opportunity to reflect on the remarkable advancements in the care for congenital heart disease (CHD). Historically viewed with a grim outlook, CHD has journeyed from a potentially lethal condition to a chronic disease managed into adulthood.
Developments in cardiovascular (CV) surgery and related care have led to the improved survival of patients with congenital heart disease (CHD) and more teenagers and adults living with congenital heart disease (ACHD).
In this episode, the focus is on congenital heart disease. In this panel discussion, host Andrea Price MS, AACC brings together Tricia Keegan, NP, DNP, FACC, Disty Pearson, PA-C, AACC, and Bailey Estes MSN, AGNP-C, to explore best practices related to structural heart disease.
For adults with congenital heart disease (ACHD), those with heart failure (HF) hospitalizations have an increased risk for mortality and morbidity, according to a study published in the Dec. 5 issue of the Journal of the American Heart Association.
Research Highlights: Newborns with congenital heart defects may have a higher risk of developing childhood cancer compared to children born without a heart abnormality. Congenital heart defects in newborns may also signal an elevated cancer risk for.
Prenatal diagnosis of congenital heart defects—the most common birth defects in the United States—is associated with improved outcomes. Despite its importance, however, overall prevalence of prenatal diagnosis is low (12–50%).
This year saw exciting developments in the treatment of pediatric and congenital heart disease. Transcatheter pulmonary valve replacement (TPVR) continued to dominate the field of interventional cardiology.
6, 2025 Medtronic plc hasannounced it received CE ( Conformit Europenne ) Mark for the Harmony Transcatheter Pulmonary Valve (TPV) System, a minimally invasive alternative to open-heart surgery for congenital heart disease patients with native or surgically repaired right ventricular outflow tract (RVOT). 1 Hoffman JL, Kaplan S.
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center.
Over the past decade, new research has advanced scientific knowledge of neurodevelopmental trajectories, factors that increase neurodevelopmental risk, and neuroprotective strategies for individuals with congenital heart disease. It also includes an updated algorithm for referral, evaluation, and management of individuals at high risk.
Due to improvements in recognition and management of their multisystem disease, the long‐term survival of infants, children, and adolescents with trisomy 21 and congenital heart disease now matches children with congenital heart disease and no genetic condition in many scenarios.
addressed the safety, tolerability, and outcomes of patients with adult congenital heart disease (ACHD) treated with sodium-glucose cotransporter 2 inhibitors (SGLT2i). Neijenhuis et al. and Fusco et al.
Is engagement in vigorous exercise, including competitive sports, associated with increased risk for life-threatening ventricular arrhythmias in individuals with known and treated congenital long-QT syndrome (LQTS)?
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content