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BioCardia’s CardiAMP Cell Therapy Chronic Myocardial Ischemia Trial Results Show Patient Benefits in Important Outcomes

DAIC

a developer of cellular and cell-derived therapeutics for the treatment of cardiovascular and pulmonary diseases, today announced the primary endpoint results of the open label roll-in cohort of the CardiAMP Cell Therapy in Chronic Myocardial Ischemia Trial. Getty Images milla1cf Thu, 05/02/2024 - 10:12 May 2, 2024 — BioCardia, Inc. ,

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GE Healthcare Launches New Cardiac PET tracer

DAIC

ii to show blood flow through the heart muscle and evaluate the presence, extent and degree of myocardial ischemia or infarction. Around 6 million MPI procedures are undertaken each year in theU.S. Flyrcado is now available in selectU.S.markets.

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Patients Undergo First Doses of New Cardiac PET tracer

DAIC

Around six million MPI procedures are undertaken each year in the US [2] to show blood flow through the heart muscle and evaluate the presence, extent and degree of myocardial ischemia or infarction. National Center for Health Statistics. Multiple Cause of Death 20182022 on CDC WONDER Database.

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Flavin-containing monooxygenase 2 confers cardioprotection in ischemia models through its disulfide bond catalytic activity

Journal of Clinical Investigation - Cardiology

Myocardial infarction (MI) is characterized by massive cardiomyocyte (CM) death and cardiac dysfunction, and effective therapies to achieve cardioprotection are greatly needed. Here, we report that flavin-containing monooxygenase 2 (FMO2) levels were markedly increased in CMs in both ex vivo and in vivo models of ischemic injury.

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Nrf3-Mediated Mitochondrial Superoxide Promotes Cardiomyocyte Apoptosis and Impairs Cardiac Functions by Suppressing Pitx2

Circulation

Here, we aimed to evaluate the role and mechanism of Nrf3 in injury-induced pathological cardiac remodeling.METHODS:Global (Nrf3-KO) and CM-specific (Nrf3CM) Nrf3 knockout mice were subjected to MI or ischemia/reperfusion injury, followed by functional and histopathological analysis.