Frontiers in Cardiovascular Medicine
OCTOBER 9, 2024
ObjectivesThe discovery of pluripotent stem cell-derived cardiomyocytes (PSC-CMs) has not only deepened our understanding of the pathogenesis and progression of heart disease, but also advanced the development of engineered cardiac tissues, cardiac regenerative therapy, drug discovery and the cardiotoxicity assessment of drugs.
DAIC
JULY 25, 2024
About Chronic Heart Failure of Reduced Ejection Fraction (HFrEF) Heart failure of reduced ejection fraction (HFrEF) is a clinical condition in which the output of blood from the heart is insufficient to meet the metabolic demands of the body. CAUTION - Limited by United States law to investigational use.
DAIC
MARCH 3, 2025
CAD is the most common form of heart disease and remains the leading cause of death for men and women in the US, with 371,506 deaths reported in 2022 [1]. We are committed to growing the manufacturing footprint for Flyrcado to drive access for cardiac PET-enabled imaging centers throughout the US. National Center for Health Statistics.
Journal of Clinical Investigation - Cardiology
DECEMBER 17, 2024
Myocardial infarction (MI) is characterized by massive cardiomyocyte (CM) death and cardiac dysfunction, and effective therapies to achieve cardioprotection are greatly needed. Here, we report that flavin-containing monooxygenase 2 (FMO2) levels were markedly increased in CMs in both ex vivo and in vivo models of ischemic injury.
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