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Atrial hiPSC-CM as a pharmacological model to evaluate anti-AF drugs: Some lessons from IKur

Journal of Cardiovascular Pharmacology

We believe that the discrepancies indicate that experiments in single atrial CM (both adult atrial CM and atrial hiPSC-CM) might be misleading. Under particular experimental conditions, atrial hiPSC-CMs may not closely resemble the electrophysiology of the human atrium.