Circulation

OCTOBER 20, 2024

Circulation, Volume 150, Issue 17 , Page 1313-1314, October 22, 2024.

Heart Transplant 45

Heart Transplant Transplant Circulation 45

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146828-A4146828, November 12, 2024. Heart transplantation remains a vital treatment for end-stage heart failure, yet the scarcity of suitable donor hearts makes the treatment unavailable to many patients in critical need.

Transplant 40

Transplant Heart Transplant Heart Dysfunction Heart Failure 40

Circulation: Cardiovascular Imaging

JANUARY 15, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 1 , Page e015858, January 1, 2024. BACKGROUND:Advanced chronic kidney disease is associated with high cardiovascular risk, even after kidney transplant. years post-transplant. An abnormal MPI result was defined as a total perfusion deficit >5% of the myocardium.

Transplant 40

Transplant Coronary Artery Disease Myocardial Infarction Kidney Disease 40

Circulation: Cardiovascular Imaging

APRIL 2, 2024

Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:In heart transplant recipients, right ventricular (RV) dysfunction may occur for a variety of reasons. Whether RV dysfunction in the stable phase after heart transplantation is associated with long-term adverse outcomes is unknown. Over a median follow-up of 4.4

Heart Transplant 40

Heart Transplant Transplant Outcomes Myocardial Infarction 40

DAIC

APRIL 30, 2024

Image courtesy of Hideki Kobayashi from Shinshu University milla1cf Tue, 04/30/2024 - 12:53 April 30, 2024 — Regenerative heart therapies involve transplanting cardiac muscle cells into damaged areas of the heart to recover lost function. However, the risk of arrhythmias following this procedure is reportedly high.

Transplant 105

Transplant Heart Transplant Myocardial Infarction Heart attacks 105

Circulation

DECEMBER 18, 2023

Circulation, Ahead of Print. Last, we consider how the cardiac arrest population may make up an important pool of organ donors for those awaiting organ transplantation. Cardiac arrest is common and deadly, affecting up to 700 000 people in the United States annually.

Cardiac Arrest 81

Cardiac Arrest Transplant Circulation Outcomes 81

Circulation: Genomic and Precision Medicine

SEPTEMBER 28, 2023

Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 452-461, October 1, 2023. Background:Many cardiovascular disorders propel the development of advanced heart failure that necessitates cardiac transplantation. of patients with unexplained end-stage cardiomyopathy.

Heart Transplant 40

Heart Transplant Transplant Cardiomyopathy Pediatrics 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4123674-A4123674, November 12, 2024. Background:Transplantation arteriosclerosis is one of the major complications for the mid- and long-term survival of recipients with organ transplantation.

Transplant 40

Transplant Innovation Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146920-A4146920, November 12, 2024. Cox regression results showed that there is an increased risk of mortality in patients who did not receive transfusions before transplant (p<0.0001).Conclusion:While

Transplant 40

Transplant Heart Transplant Risk Factors Outcomes 40

Journal of Clinical Investigation - Cardiology

JANUARY 16, 2024

Accurate detection of graft-versus-host disease (GVHD) is a major challenge in the management of patients undergoing hematopoietic stem cell transplantation (HCT). Here, we demonstrated the use of circulating cell-free DNA (cfDNA) for detection of tissue turnover and chronic GVHD (cGVHD) in specific organs. BACKGROUND. CONCLUSION.

Biomarkers 69

Biomarkers Transplant Circulation Research 69

Circulation

SEPTEMBER 10, 2024

Circulation, Ahead of Print. Early identification of kidney dysfunction in patients with advanced heart failure is crucial for timely interventions. Hemodynamic derangements and maladaptive neurohormonal upregulations contribute to fluctuations in kidney indices and electrolytes that may recover with guideline-directed medical therapy.

Heart Failure 80

Heart Failure Kidney Disease Heart Transplant Transplant 80

Circulation

FEBRUARY 26, 2024

Circulation, Ahead of Print. Individual programs oftentimes develop upper age limits for various interventional strategies for their patients, including heart transplantation and durable left ventricular assist devices. Older adults have been largely excluded from analyses of therapeutic options in patients with cardiogenic shock.

Cardiogenic Shock 74

Cardiogenic Shock Best Practices Heart Transplant Transplant 74

DAIC

MAY 15, 2024

It can be used while waiting for a heart transplant, to help the heart recover, or as a permanent solution when a transplant isn't an option. It diverts blood from the weakened left ventricle and propels it into the body's main artery, the aorta, helping to circulate blood throughout the body.

Transplant 105

Transplant Heart Failure Heart Transplant Pediatrics 105

Circulation: Heart Failure

DECEMBER 9, 2024

Circulation: Heart Failure, Ahead of Print.

Heart Transplant 40

Heart Transplant Transplant Heart Failure Circulation 40

Frontiers in Cardiovascular Medicine

MARCH 5, 2024

Chronic kidney disease (CKD) significantly increases cardiovascular risk and mortality, and the accumulation of uremic toxins in the circulation upon kidney failure contributes to this increased risk.

Kidney Disease 59

Kidney Disease Transplant Circulation 59

Circulation: Heart Failure

AUGUST 1, 2024

Circulation: Heart Failure, Ahead of Print.

Heart Transplant 40

Heart Transplant Education Transplant Heart Failure 40

DAIC

APRIL 15, 2024

It can be used while waiting for a heart transplant, to help the heart recover, or as a permanent solution when a transplant isn't an option. They divert blood from the weakened left ventricle and propel it into the body's main artery, the aorta, helping to circulate blood throughout the body.

Transplant 105

Transplant Heart Transplant Pediatrics Heart Failure 105

Circulation: Cardiovascular Imaging

JANUARY 15, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 1 , Page e016408, January 1, 2024.

Transplant 40

Transplant Cardiovascular Imaging Circulation 40

Circulation

FEBRUARY 12, 2024

Circulation, Ahead of Print. BACKGROUND:Much of our knowledge of organ rejection after transplantation is derived from rodent models.METHODS:We used single-nucleus RNA sequencing to investigate the inflammatory myocardial microenvironment in human pediatric cardiac allografts at different stages after transplantation.

Transplant 45

Transplant Pediatrics Circulation 45

Circulation: Heart Failure

DECEMBER 11, 2023

Circulation: Heart Failure, Ahead of Print.

Heart Transplant 40

Heart Transplant Transplant Heart Failure Circulation 40

Circulation: Heart Failure

FEBRUARY 5, 2024

Circulation: Heart Failure, Ahead of Print. BACKGROUND:Cardiac allograft vasculopathy (CAV) is the leading cause of late graft dysfunction in heart transplantation. The 5-year risk (95% CI) of the International Society for Heart and Lung Transplantation–defined CAV in the high, moderate, low, and very low risk groups was 49.1% (35.2%–68.5%),

Heart Transplant 40

Heart Transplant Ultrasound Transplant Heart Failure 40

Circulation: Heart Failure

NOVEMBER 6, 2023

Circulation: Heart Failure, Ahead of Print.

Heart Transplant 40

Heart Transplant Transplant Heart Failure Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146823-A4146823, November 12, 2024. Heart transplant rates were low but increased slightly in 2020 for patients without CHD, with DV and SV CHD patients showing fluctuating rates peaking in 2018 and 2019, then declining in 2020. Patients without CHD were older (mean age 71.5

Cardiogenic Shock 40

Cardiogenic Shock Congenital Heart Disease Heart Failure Congenital 40

DAIC

MARCH 8, 2024

Cardiac transplantation, the only option for many patients, is severely restricted by the limited availability of donor hearts. As an alternative therapeutic option, LVAD heart pumps have been implanted to help patients with end-stage heart failure sustain blood circulation in the body. The research is funded by a four-year, $7.8

Blood Clot 98

Blood Clot Heart Failure Quality of Life Innovation 98

Circulation

DECEMBER 17, 2024

Circulation, Ahead of Print. We explored the mechanism of METTL4 involvement in atherosclerosis usingMettl4Mac-KO-Apoe-/-andMettl4MUT-Apoe-/-mice and cell models, as well as bone marrow transplantation. BACKGROUND:Mitochondrial dysfunction is a key factor in the development of atherogenesis.

Atherosclerosis 40

Atherosclerosis Transplant Plaque Pharmacology 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4113494-A4113494, November 12, 2024. End-stage ischemic heart disease necessitates heart transplantation, and emerging cell therapy presents a promising solution to address donor scarcity.

Ischemia 40

Ischemia Transplant Heart Transplant Biomarkers 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142247-A4142247, November 12, 2024. Background:Cardiac transplantation remains the single most effective treatment for end-stage heart failure. Autoradiography revealed68Ga-grazytracer accumulation in the transplanted heart. at POD 7 days; P<0.001).

Transplant 40

Transplant Heart Failure Circulation Outcomes 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page ASa1109-ASa1109, November 12, 2024. We assessed the correlates of predicted peak VO2, and the relationship between predicted peak VO2quartiles and cardiovascular outcomes (death/transplant).Results:Of Results:Of 323 patients (age 29±9 years; 177 [55%] men), the median peak VO2 was 19.1

Transplant 40

Transplant Outcomes Exercise Cardiovascular Disease 40

Circulation: Heart Failure

FEBRUARY 13, 2024

Circulation: Heart Failure, Ahead of Print. BACKGROUND:Cardiac allograft rejection is the leading cause of early graft failure and is a major focus of postheart transplant patient care.

Transplant 40

Transplant Heart Failure Patient Care Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4145296-A4145296, November 12, 2024. Aortic valve stenosis (AS) is often a contraindication to liver transplantation (LT). Aortic valve peak velocity (AVVmax) increased steadily as patients neared transplant and dropped significantly immediately after transplantation (Figure 1A).

Aortic valve 40

Aortic valve Aortic Transplant Stenosis 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4144461-A4144461, November 12, 2024. Introduction:Left ventricular assist devices (LVADs) have become an increasingly common treatment option for patients with advanced heart failure, serving as either a bridge to transplantation or destination therapy.

Transplant 40

Transplant Risk Factors Heart Failure Circulation 40

Circulation: Heart Failure

FEBRUARY 1, 2024

Circulation: Heart Failure, Ahead of Print. BACKGROUND:In 2018, an algorithm-based allocation system for heart transplantation (HT) was implemented in France. The cumulative incidence of waitlist mortality estimated with competing risk analysis and incidence of transplantation were compared between diagnosis groups.

Heart Failure 40

Heart Failure Congenital Heart Disease Congenital Outcomes 40

Circulation: Heart Failure

DECEMBER 9, 2024

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Transplant 40

Transplant Pediatrics Heart Disease Pulmonary 40

Circulation: Heart Failure

DECEMBER 10, 2024

Circulation: Heart Failure, Ahead of Print. BACKGROUND:Cardiac allograft vasculopathy (CAV) leads to impaired myocardial blood flow (MBF), increasing the risk of cardiovascular death or retransplant among heart transplantation (HT) recipients.

Coronary Angiogram 40

Coronary Angiogram Heart Transplant Heart Failure Transplant 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4134590-A4134590, November 12, 2024. The association between a lower rate of MAE and EMB persisted in the multivariate model when those with heart transplant who had EMB were compared to those without heart transplant who did not have EMB p=0.001.

Cardiomyopathy 40

Cardiomyopathy Pediatrics Heart Transplant Heart Failure 40

Dr. Smith's ECG Blog

DECEMBER 5, 2023

References Law YM, Lal AK, Chen S, Čiháková D, Cooper LT Jr, Deshpande S, Godown J, Grosse-Wortmann L, Robinson JD, Towbin JA; American Heart Association Pediatric Heart Failure and Transplantation Committee of the Council on Lifelong Congenital Heart Disease and Heart Health in the Young and Stroke Council. Circulation. Circulation.

Pediatrics 112

Pediatrics Pericarditis COVID-19 Congenital Heart Disease 112

Circulation

FEBRUARY 15, 2024

Circulation, Ahead of Print. BACKGROUND:Clonal hematopoiesis of indeterminate potential (CHIP), a common age-associated phenomenon, associates with increased risk of both hematological malignancy and cardiovascular disease.

Atrial Fibrillation 45

Atrial Fibrillation Diet Myocardial Infarction Cardiovascular Disease 45