Circulation: Heart Failure

FEBRUARY 21, 2025

Circulation: Heart Failure, Ahead of Print.

Thrombosis 40

Thrombosis Heart Failure Circulation 40

EMS 12-Lead

SEPTEMBER 6, 2022

Coronary thrombosis is a dynamic process of platelet aggregation and subsequent coagulation. During spontaneous reperfusion -- whether via thrombolysis, or recruitment of collateral circulation -- there exists characteristic ST/T changes on the ECG. Case Review: [link]

Thrombosis 52

Thrombosis Thrombolysis Circulation 52

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. Circulation [Internet] 2017;135(16):1481–9. Circulation.

Coronary Angiogram 109

Coronary Angiogram Plaque Thrombosis STEMI 109

Dr. Smith's ECG Blog

MAY 19, 2020

Coronary thrombosis or embolism can result in MINOCA, either with or without a hypercoagulable state. The gold standard technique for diagnosing coronary spasm is administration of high-dose intracoronary acetylcholine boluses with the response evaluated by invasive contrast angiography.

Defibrillator 52

Defibrillator Circulation Plaque Cardiac Arrest 52

Circulation: Cardiovascular Interventions

JANUARY 24, 2024

Circulation: Cardiovascular Interventions, Ahead of Print. Principal safety outcomes were independently adjudicated International Society on Thrombosis and Haemostasis major bleeding at 72 hours post-treatment and mortality within 12 months of treatment.

Embolism 75

Embolism Thrombolysis Ultrasound Pulmonary 75

Cardiometabolic Health Congress

JANUARY 16, 2025

A 2022 study published in Circulation demonstrated that earlier LDL-C reduction leads to compounded cardiovascular benefits over time. Studies, such as those published in JACC (2022) , show that early identification can lead to targeted interventions, reducing long-term risk.

Atherosclerosis 59

Atherosclerosis Risk Factors Coronary Artery Disease Cardiovascular Disease 59

Stroke Journal

OCTOBER 31, 2024

Thrombosis is the main pathological process of stroke and is therefore an important therapeutic target in stroke prevention. Circulating immune cells have been found to induce immunothrombosis, and they actively participate in the formation of the thrombus by promoting platelet recruitment and thrombin activation.

Stroke 40

Stroke Strokes Thrombosis Plaque 40

Stroke Journal

JANUARY 30, 2025

Direct oral anticoagulants (DOACs) are approved in many countries for the treatment and prevention of pediatric venous thrombosis but its use in pediatric arterial thrombosis is less established. Patients treated for concomitant venous thrombosis and/or without follow up imaging were excluded. Data was de-identified and SAS 8.3

Pediatrics 40

Pediatrics Stroke Strokes Thrombosis 40

Dr. Smith's ECG Blog

SEPTEMBER 18, 2024

5 We are aware that the current consensus is that the propensity for plaques to rupture is independent of plaque size; however, in our opinion, the hypothesis that small atherosclerotic plaques are the most likely to rupture, with resulting occlusive thrombosis, is unproven. These are typical findings at sites of plaque rupture.

Ischemia 121

Ischemia Plaque Stenosis Myocardial Infarction 121

DAIC

OCTOBER 16, 2024

16, 2024 — Sahajanand Medical Technologies (SMT) recently announced the publication of the COMPARE 60/80 HBR trial results in Circulation: Cardiovascular Interventions , a journal of The American Heart Association. tim.hodson Wed, 10/16/2024 - 09:00 Oct. Led by Dr. Pieter C.

Stent 52

Stent Stents Thrombosis Coronary Artery Disease 52

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4141755-A4141755, November 12, 2024. However, it subjects patients to lifelong warfarin therapy after MHVR, with the attendant risk of bleeding and thrombosis. Background:Mechanical heart valve replacement (MHVR) is an effective method for the treatment of severe heart valve disease.

Heart Valves 40

Heart Valves Embolism Thrombosis Quality of Life 40

Journal of Cardiovascular Pharmacology

SEPTEMBER 5, 2024

Heparin, the most utilized anticoagulant, carries concerns for heparin-induced thrombocytopenia and possible resistance given its dependence on co-factors and circulating proteins to exert its pharmacologic effect.

Laboratory 40

Laboratory Thrombosis Pharmacology Pulmonary 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142117-A4142117, November 12, 2024. Introduction:The management of patients with Venous thromboembolism (VTE) receiving anticoagulant therapy is complicated by potential interactions with other medications, including antibiotics.

Thrombosis 40

Thrombosis Circulation 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionDespite technical advances in mechanical thrombectomy (MT), failure to achieve recanalization in the posterior circulation remains a significant challenge. Rescue strategies to increase MT success in the posterior circulation have been explored. The off‐label use of DES for intracranial pathologies continues to expand.

Stent 40

Stent Stents Thrombosis Thrombolysis 40

American College of Cardiology

FEBRUARY 1, 2025

7 The use of antiplatelet agents to prevent stent thrombosis, moderate- to high-dose statin therapy after acute coronary syndromes, or antihypertensive agents in asymptomatic patients may all be perceived by patients as not providing benefit because they may not feel the effects.8 Circulation. Circulation. BMC Med2015;13(74).

Cardiovascular Disease 40

Cardiovascular Disease Coronary Artery Disease CMS Hospital 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4137144-A4137144, November 12, 2024. Introduction:Subacute stent thrombosis (ST) is related to high rates of cardiac reinfarction. He had CCS Class IV CP despite medical therapy and returned for re-look CA with TIMI-3 flow in the left-sided circulation without thrombus (Fig 1b).

Chest Pain 40

Chest Pain Coronary Artery Disease Angioplasty Thrombosis 40

Stroke Journal

JANUARY 30, 2025

Compared to AF-LVOS, ICAS-LVOS patients exhibited associations with younger age (OR: 0.947; P = 0.043), previous stroke (OR: 4.749; P = 0.017), posterior circulation involvement (OR: 6.417; P = 0.017), higher fibrinogen levels (OR: 2.049; P = 0.023), and higher triglyceride levels (OR: 2.905; P = 0.019).

Atherosclerosis 40

Atherosclerosis Stroke Strokes Atrial Fibrillation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4145271-A4145271, November 12, 2024. A 42-year-old female with SLE, lupus cerebritis with related seizure disorder, and mesenteric venous thrombosis on warfarin initially presented for syncope. Acute stroke workup was negative, and syncope was attributed to possible brief seizure.

Embolism 40

Embolism Thrombosis Stroke Strokes 40

Dr. Smith's ECG Blog

NOVEMBER 15, 2013

Circulation 1991;84:1454-1455. It is important to recognize that coronary thrombosis is dynamic , with spontaneous opening and lysing of the thrombus in the infarct-related artery (we all have endogenous tPA and plasmin to lyse thrombi). Consequences of reocclusion after successful reperfusion therapy in acute myocardial infarction.

Chest Pain 52

Chest Pain Thrombosis Myocardial Infarction STEMI 52

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146624-A4146624, November 12, 2024. However, complications – such as hemolysis, thrombosis, degradation of the von Willebrand factor, and gastrointestinal bleeding – stand in the way of their widespread application.

Thrombosis 40

Thrombosis Transplant Heart Failure Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142012-A4142012, November 12, 2024. At the time of discharge, LV systolic function improved to 39% and there were no findings concerning for coronary artery thrombosis or fistula repair failure. No murmur or extra heart sound were heard, and the lung sounds were normal.

Coronary Artery Bypass Graft 40

Coronary Artery Bypass Graft ACE Inhibitor Coronary Angiogram Aneurysm 40

Stroke Journal

FEBRUARY 1, 2024

Prolonged ICU stay were more likely to have higher baseline median NIHSS score (19 vs. 14%, p < 0.0001), posterior circulation stroke (12.6% vs. 6.1%, p = 0.0002), deep vein thrombosis (7.3 vs. 5.7%, p = 0.0200), intubation for the procedure (86.7% vs. 69.3%, p = 0.0001), complications including pneumonia (18.5%

ICU 40

ICU Thrombolysis Stroke Strokes 40

Stroke Journal

FEBRUARY 1, 2024

We determined the number of patients who were admitted with AIS due to thrombosis or embolism of anterior circulation arteries and those who received MT in a particular region/state based on the State Inpatient Database of NIS.

Stroke 40

Stroke Strokes Inpatient Thrombosis 40

Dr. Smith's ECG Blog

NOVEMBER 30, 2022

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection. link] We know that most type 1 acute MI due to plaque rupture and thrombosis occurs in lesions that are less than 50% (see Libby reference). Circulation.

Plaque 52

Plaque Chest Pain Thrombosis Stenosis 52

DAIC

FEBRUARY 18, 2025

tim.hodson Tue, 02/18/2025 - 16:41 Feb. The dataset suggests tracking clinic-reported outcome measures at six months within the first year after diagnosis and annually thereafter, and patient-reported outcomes annually, with more frequent tracking advised for patients who undergo either a surgical or transcatheter procedure.

Heart Valves 52

Heart Valves Quality of Life Cardiothoracic Outcomes 52

Stroke Journal

FEBRUARY 1, 2024

Background and Objectives:Understanding the mechanisms of thrombosis is crucial for the future advancement in treating ischemic stroke. After adjusting for potential confounders including posterior circulation occlusion, serum hemoglobin levels, serum albumin levels, and the presence of active cancer (all p<0.05

Thrombosis 40

Thrombosis Stroke Strokes Cancer 40

Circulation

FEBRUARY 12, 2024

Circulation, Ahead of Print. The secondary outcomes included ischemia-driven target lesion revascularization, target vessel myocardial infarction, death, cardiac death, target vessel revascularization, stent thrombosis, and major adverse cardiac events. Frequentist random-effects network meta-analyses were conducted.

Ultrasound 67

Ultrasound Myocardial Infarction Thrombosis Stent 67

Circulation: Cardiovascular Interventions

MARCH 30, 2025

Circulation: Cardiovascular Interventions, Ahead of Print. Endpoints included major adverse cardiovascular events (MACE), cardiac death, myocardial infarction (MI), periprocedural MI, all-cause mortality, stent thrombosis (definite or probable), and target vessel revascularization (TVR). 0.76; p=0.003), MI (RR 0.75; 95%CI 0.59-0.96;

Thrombosis 40

Thrombosis Myocardial Infarction Stent Stents 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4145424-A4145424, November 12, 2024. The outcome was any 30-day event defined as death, stent thrombosis, major bleeding events, and composites of ischemic and bleeding events. 41% patients were treated with immediate dual therapy, and 59% were discharged on triple therapy.

Thrombosis 40

Thrombosis Outcomes Stent Stents 40

Stroke Journal

JANUARY 21, 2024

BACKGROUND:Sex-specific differences in plaque composition and instability underscore the need to explore circulating markers for better prediction of high-risk plaques. Antagonistic interactions between sex and white blood cell (WBC) counts, basophil-to-WBC ratio, and platelet counts influenced plaque instability.

Plaque 40

Plaque Circulation Atherosclerosis Hemorrhage 40

DAIC

MARCH 8, 2024

As an alternative therapeutic option, LVAD heart pumps have been implanted to help patients with end-stage heart failure sustain blood circulation in the body. However, there are shortcomings associated with LVAD implantation: complications include infection, blood clotting (thrombosis), stroke and bleeding.

Blood Clot 98

Blood Clot Heart Failure Quality of Life Innovation 98

Circulation

NOVEMBER 23, 2023

Circulation, Ahead of Print. 3.30]) and subacute definite or probable stent thrombosis (0.58% and 0.17%; hazard ratio, 3.40 [95% CI, 1.26–9.23]) mg/day) monotherapy or to DAPT with aspirin (81–100 mg/day) and prasugrel (3.75 mg/day) after loading of 20 mg of prasugrel in both groups. years; men, 76.6%; acute coronary syndrome, 75.0%).

Stent 40

Stent Stents Thrombosis Myocardial Infarction 40

Circulation

APRIL 7, 2025

Circulation, Ahead of Print. Black patients had higher rates of medical complications in the perioperative period, including acute renal failure (subdistribution HR, 1.18 [95% CI, 1.011.38]), dialysis initiation (subdistribution HR, 2.75 [95% CI, 2.033.7]), and deep vein thrombosis (subdistribution HR, 1.54 [95% CI, 1.052.26]).

Aneurysm 45

Aneurysm Medicare Aortic Outcomes 45

DAIC

JANUARY 23, 2024

Inflammation driven by signaling cytokines, circulating immune cells, adhesion molecules, and oxidized low-density lipoprotein cholesterol (LDL-C) leads to atherosclerotic plaque development, plaque progression, and eventual rupture.14,15 2019 Sep 10;140(11):e649-e650] [published correction appears in Circulation. Circulation.

Cardiovascular Disease 111

Cardiovascular Disease Heart attacks Heart Attack Coronary Artery Disease 111

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4139677-A4139677, November 12, 2024. She had idiopathic ventricular fibrillation in 1992, treated with an EPD (Picture 1A), later replaced by a transvenous ICD.She was diagnosed with left femoral deep venous thrombosis and bilateral pulmonary embolism and started on therapeutic anticoagulation.

Defibrillator 40

Defibrillator Cardiac Arrest Sudden Cardiac Death Coronary Angiogram 40

Stroke Journal

DECEMBER 9, 2024

Anticardiolipin antibodies, anti-2-glycoprotein I antibodies, and lupus anticoagulant were assessed using the guidelines of the International Society on Thrombosis and Haemostasis.RESULTS:aPL prevalence was 22% in patients with MMA and 25% in controls (P=0.74) with no differences in aPL subtypes between the 2 groups.

Cerebrovascular Disease 40

Cerebrovascular Disease Thrombosis Hemorrhage Stroke 40

Stroke Journal

JANUARY 30, 2025

Introduction:Venous thromboembolism (VTE)manifesting as deep vein thrombosis (DVT) and pulmonary embolus (PE) and arterial thromboembolism (ATE) manifesting as acute ischemic stroke (AIS) result in ~1 million US deaths annually. Stroke, Volume 56, Issue Suppl_1 , Page ATP7-ATP7, February 1, 2025.

Thrombosis 40

Thrombosis Pulmonary Stroke Strokes 40