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BackgroundPostoperative blood glucose levels significantly impact outcomes in cardiac surgery patients undergoing extracorporeal circulation (ECC) auxiliary to open heart surgery. While hypoglycemia and hyperglycemia are known riskfactors for adverse outcomes, the optimal glycemic range for patients undergoing ECC remains unclear.
Background We evaluated the potential of circulating bone morphogenetic protein 10 (BMP10) as a biomarker for atrial stress and remodelling in patients with heart failure (HF), in comparison to N-terminal pro-B-type natriuretic peptide (NT-proBNP). We also assessed the predictive value of BMP10 for adverse clinical outcomes.
And plaque in your coronary arteries is the result of exposure to riskfactors over time. These individuals then must have had one or more riskfactors for a long time prior to their heart attack. The answer: RiskFactors. But wouldn’t such riskfactors have been obvious?
Insulin resistance is a major riskfactor for the leading causes of death, the leading one being cardiovascular disease. Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers. The key is to identify risk much earlier. Circulation.
Patients who present with persistent atrial fibrillation at diagnosis are more likely to have certain riskfactors as compared with patients with occasional atrial fibrillation (AFib). The findings, led by investigators in the Smidt Heart Institute at Cedars-Sinai, published in Circulation: Arrhythmia and Electrophysiology.
Circulation, Ahead of Print. Most adverse trends are projected to be worse among people identifying as American Indian/Alaska Native or multiracial, Black, or Hispanic.CONCLUSIONS:The prevalence of many cardiovascular riskfactors and most established diseases will increase over the next 30 years. in 2020 to 61.0%
Adults younger than 35 to 45 years old may have a higher risk of developing a stroke from nontraditional riskfactors such as migraines than from traditional risks like high blood pressure. That's according to new research published today in Circulation: Cardiovascular Quality and Outcomes.
Explore actionable, evidence-based strategies to combat traditional and emerging riskfactors, with a focus on precision approaches and primordial prevention. Precision Medicine: Personalizing Prevention for Better Outcomes Precision medicine provides tools to customize prevention and treatment plans based on individual riskfactors.
Objective:Forward head posturing (FHP) has been associated with chronic anatomic vertebral artery disturbances possibly leading to posterior circulation ischemia. The data supporting FHP as a true riskfactor of posterior circulation stroke has not been well established. There was a significant difference of 5.2
New Cleveland Clinic and Tufts University research shows that elevated levels of the gut microbiome trimethylamine N-oxide (TMAO) pathway led to a higher risk of heart failure independent of other riskfactors, according to a study of two large National Institutes of Health cohorts.
A projected rise in heart disease and stroke – along with several key riskfactors, including high blood pressure and obesity – is likely to triple related costs to $1.8 trillion by 2050, according to two presidential advisories published in the AHA journal Circulation. Obesity rates are expected to climb from 43.1%
Circulation, Volume 150, Issue Suppl_1 , Page A4148106-A4148106, November 12, 2024. Owing to improved management, the life expectancy of patients with hemophilia has increased significantly and predisposes them to risk of cardiovascular diseases and thrombotic events.
mg tablet), ananti-inflammatory atheroprotective cardiovascular treatment, to reduce the risk of myocardial infarction (MI), stroke, coronary revascularization, and cardiovascular death in adult patients with established atherosclerotic disease or with multiple riskfactors for cardiovascular disease.
Background:Small studies have found that patients presenting with posterior circulation ischemic strokes are more likely than patients with anterior circulation strokes to suffer a missed or delayed diagnosis in the ED. 2.66) and mixed territory cases (adjusted OR, 2.03; 95% CI, 1.62-2.55).Conclusions:Patients
Circulation, Ahead of Print. Resistance training not only can improve or maintain muscle mass and strength, but also has favorable physiological and clinical effects on cardiovascular disease and riskfactors.
Circulation, Ahead of Print. The human capital approach was used to estimate productivity losses from morbidity and premature mortality due to cardiovascular conditions.RESULTS:One in 3 US adults received care for a cardiovascular riskfactor or condition in 2020.
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. However, routine outpatient visits and cardiovascular riskfactor screening did not return back to pre-pandemic levels, while riskfactor treatment remained stable.
Circulation, Volume 151, Issue 10 , Page 716-732, March 11, 2025. Albuminuriaincreased urine albumin excretionis associated with cardiovascular mortality among patients with diabetes, hypertension, chronic kidney disease, or heart failure, as well as among adults with few cardiovascular riskfactors.
The Consequences of High Cholesterol Why high cholesterol is more than just a number—it’s a major riskfactor for heart disease and stroke. Circulation. How to interpret your cholesterol numbers and understand what they mean for your health. 2025 Jan 27.
Circulation, Volume 150, Issue Suppl_1 , Page A4141868-A4141868, November 12, 2024. Inflammatory responses result from coordinated actions of circulating molecular mediators and circulating immune cells (CIC). Taken together, our data reveal unexpected insights into the interplay of CIC, inflammatory risk, and ASCVD.
Circulation, Volume 150, Issue Suppl_1 , Page A4140513-A4140513, November 12, 2024. Aims:Asian Americans experience disproportionate burdens of cardiovascular riskfactors and cardiovascular disease (CVD). However, the trends in cardiovascular risks in adults from different Asian ethnic backgrounds remain understudied.
Circulation, Volume 150, Issue Suppl_1 , Page A4141434-A4141434, November 12, 2024. Intro:Obesity is a critical riskfactor for cardiometabolic disease.
Heart disease is the leading cause of death among women, and women who have complications during pregnancy, such as high blood pressure or gestational diabetes, have a significantly higher risk of heart disease and stroke later in life, according to a new scientific statement from the American Heart Association, published in Circulation.
Lp(a) is emerging as an important, yet under-recognized, potential riskfactor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. Circulation. The development of the Tina-quant Lipoprotein (a) Gen.2 Arnett DK et al.
Circulation, Ahead of Print. In addition, in recognition that high-quality cardiac rehabilitation programs regularly monitor their processes and outcomes and engage in an ongoing process of quality improvement, we introduce a new core component of program quality.
Circulation, Volume 150, Issue Suppl_1 , Page A4141224-A4141224, November 12, 2024. However, as a specific subgroup of ACS, a significant proportion of patients with ACS without standard modifiable cardiovascular riskfactors (SMuRFs) are currently being identified.
Circulation, Volume 150, Issue Suppl_1 , Page A4137359-A4137359, November 12, 2024. p<0.001)Conclusions:The lower summations of ST–T area assessed by a computerized quantitative method were associated with increased risk of cardiovascular disease, especially ischemic stroke, in patients with one or more cardiovascular riskfactors.
Heart disease remains one of the leading causes of death worldwide, often attributed to a mix of lifestyle choices, environmental factors, and genetic predispositions. This blog explores how genetics influence heart health and whether mitigating these inherited risks is possible. Can You Prevent Heart Disease if Its in Your Genes?
The real question is what the Tsimane tribe's riskfactor profile looks like. Because if we can understand that, we can attempt to emulate it and also considerably delay the onset of cardiovascular disease and our risk of an early death as a consequence of it. Minimising cardiovascular risk is possible. Circulation.
Introduction:Previous studies have suggested that increased body fat is associated with elevated cardiovascular disease (CVD) risk. We have previously shown that apart from common vascular riskfactor modification, adipose tissue-specific factors, such as adiponectin, may mediate the relationship between body fat and vascular risk.
Targeted proteomic profiling identified the circulating inflammatory proteins. These events may promote atherosclerotic plaque formation, a riskfactor for ischemic stroke and worsen brain damage. Carotid plaques were examined using hematoxylin and eosin staining.
Steno-occlusive changes in the posterior cerebral arteries (PCAs) may contribute to worsened outcomes in patients with MMD; however, there is little information on the incidence and natural history of posterior circulation MMD (PCMMD).
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. To reduce morbidity and mortality rates of cardiovascular disease, an urgent need exists to improve cardiovascular health among US adults. High-quality primary care is person-centered, team-based, community-aligned, and designed to provide affordable optimized health care.
Herein, we provide an overview of the current knowledge on the pathophysiology and riskfactors for AF in adult congenital heart disease, with a special focus on the existing challenges in AF ablation. Emerging imaging modalities and ablation techniques might have a role to play.
to 8 per 100,000 children per year with 15-22% occurring in the posterior circulation. Vertebral artery dissection(VAD) is a known cause of posterior circulation ischemic stroke in approx 7% of cases.Pediatric Bow Hunter syndrome, usually presents distinctively with VAD and stroke. It most commonly involves the V3 segment.In
If there is any evidence of atherosclerosis, modifiable CAD riskfactors should be treated aggressively. Medications (aspirin, statin, beta-blockers, clopidogrel, angiotensin-converting enzyme inhibitors/angiotensin-receptor blockers) should be considered on the basis of the underlying mechanism for MINOCA in each individual.
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