Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4120743-A4120743, November 12, 2024. However, the most recurrent cardiac complication in RASopathies is pulmonary valve stenosis (PVS). Backgound:The RASopathies are developmental syndromes resulting from variants in the RAS/mitogen-activated protein (MAPK) cascade.

Stenosis 75

Stenosis Pulmonary Cardiomyopathy Circulation 75

Frontiers in Cardiovascular Medicine

FEBRUARY 14, 2024

Background Pulmonary embolism is a condition of right cardiac dysfunction due to pulmonary circulation obstruction. Malignant tumor-induced pulmonary embolism, which has a poor therapeutic outcome and a significant impact on hemodynamics, is the cause of sudden death in patients with malignant tumors.

Embolism 64

Embolism Pulmonary Blood Pressure Hospital 64

Circulation: Cardiovascular Interventions

JANUARY 24, 2024

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Prior clinical trials have demonstrated the efficacy of ultrasound-facilitated catheter-directed thrombolysis (USCDT) for the treatment of acute intermediate-risk pulmonary embolism (PE) using reduced thrombolytic doses and shorter infusion durations.

Embolism 75

Embolism Thrombolysis Ultrasound Pulmonary 75

Frontiers in Cardiovascular Medicine

JANUARY 13, 2025

Valvular heart disease (VHD) leading to inadequate hemodynamic circulation is a major cause of cardiovascular morbidity and mortality worldwide. Right ventricular-pulmonary artery (RVPA) coupling integrates the ability of RV contractility to adapt to increased pulmonary arterial afterload.

Pulmonary 52

Pulmonary Heart Disease Circulation Outcomes 52

MIBHS

OCTOBER 15, 2024

This is where coronary circulation comes into play. Coronary circulation refers to the movement of blood through the network of coronary arteries and veins that supply the heart muscle (myocardium) itself. Step-by-Step Breakdown of Coronary Circulation 1.

Circulation 52

Circulation Heart Attack Heart attacks Chest Pain 52

Frontiers in Cardiovascular Medicine

MAY 8, 2024

Patients with pulmonary hypertension associated with a left-right shunt include a wide spectrum of pathophysiological substrates, ranging from those characterized by pulmonary over-circulation to those with advanced pulmonary vascular disease.

Congenital Heart Disease 52

Congenital Heart Disease Pulmonary Hypertension Congenital 52

Journal of the American Heart Association

DECEMBER 8, 2023

BackgroundData on the use of implanted hemodynamic monitoring (IHM) in patients with Fontan circulation are limited. Procedural complications (access site hematomas, pulmonary artery staining) occurred in 3 patients, without device‐related procedural complications. versus 0.6 [0–2.3];P=0.268), Device‐related complications were low.

Circulation 49

Circulation Heart Failure Pulmonary Hospital 49

Circulation

MARCH 7, 2024

Circulation, Ahead of Print. Balloon pulmonary angioplasty continues to gain traction as a treatment option for patients with chronic thromboembolic pulmonary disease with and without pulmonary hypertension.

Angioplasty 45

Angioplasty Pulmonary Hypertension Document 45

Heart BMJ

MARCH 22, 2024

Objective In Fontan circulation, pulmonary arterial hypertension (PAH)-targeted therapies could improve the patients’ exercise capacity. This study aimed to investigate the effects of PAH agents on different exercise parameters in stable Fontan patients by synthesising evidence of randomised controlled trials (RCTs).

Exercise 40

Exercise Circulation Pulmonary Pharmacology 40

Frontiers in Cardiovascular Medicine

DECEMBER 20, 2023

Massive pulmonary embolism (MPE) carries significant 30-day mortality and is characterized by acute right ventricular failure, hypotension, and hypoxia, leading to cardiovascular collapse and cardiac arrest. Veno-venous ECMO can support oxygenation but is not designed to help circulation.

Embolism 56

Embolism Pulmonary Cardiac Arrest Hemorrhage 56

Journal of the American Heart Association

MARCH 8, 2024

This approach allowed us to evaluate the effect of childhood body size on 11 measures of right heart and pulmonary circulation independent of other anthropometric traits at various stages in the lifecourse. 0.33];P=3×10−7) independent of adulthood body size.

Pulmonary 40

Pulmonary Circulation Physiology 40

Medical Xpress - Cardiology

MARCH 4, 2025

High-risk acute pulmonary embolism affects around 5% of all pulmonary embolisms and can take a dramatic course even in young people. Acute obstruction of the pulmonary circulation by a blood clot can lead to circulatory failure with a high mortality rate.

Embolism 40

Embolism Pulmonary Blood Clot Circulation 40

Circulation

JANUARY 12, 2024

Circulation, Ahead of Print. The dysfunction of pulmonary artery endothelial cells plays a pivotal role in the initiation and progression of pulmonary hypertension (PH). BACKGROUND:Pulmonary hypertension, characterized by vascular remodeling, currently lacks curative therapeutic options.

Pulmonary 45

Pulmonary Hypertension Biomarkers Circulation 45

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146398-A4146398, November 12, 2024. Rationale:Pulmonary arterial hypertension (PAH) is a devastating disease characterized by a progressive rise in pulmonary vascular resistance and occlusive vascular remodeling, leading to right heart failure and premature death.

Pulmonary 40

Pulmonary Hypertension Heart Failure Circulation 40

Frontiers in Cardiovascular Medicine

MAY 12, 2024

BackgroundAcute pulmonary embolism (APE) is a common and potentially fatal cardiovascular disease that can lead to sudden cardiac arrest in severe cases. For patients with concurrent main pulmonary artery embolism and bleeding, balloon pulmonary angioplasty may be an option.

Embolism 40

Embolism Pulmonary Hemorrhage Cardiac Arrest 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4143390-A4143390, November 12, 2024. Introduction:Obesity is rising in prevalence worldwide and co-exists in patients with group 1 pulmonary hypertension (PH). Despite having group 1 PH, pulmonary capillary wedge pressure (PCWP) was higher with obesity (13.8 ± 6.3 vs 10.4 ± 6.5

Obesity 40

Obesity Pulmonary Hypertension Diabetes 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142839-A4142839, November 12, 2024. Introduction:Inflammation is a key driver in the development of pulmonary arterial hypertension (PAH). The pulmonary vasculature was evaluated histologically. The gut microbiome is a complex ecosystem consisting of trillions of organisms, 0.1%

Pulmonary 40

Pulmonary Hypertension Innovation Exercise 40

Circulation: Heart Failure

JANUARY 8, 2025

Circulation: Heart Failure, Ahead of Print. Overall, the mean pulmonary capillary wedge pressure before LVAD implantation was 259 mm Hg. The primary outcome was 1-year survival. The median follow-up was 364 days (interquartile range, 326381 days).

Quality of Life 76

Quality of Life Heart Failure Pulmonary Cardiomyopathy 76

Circulation: Cardiovascular Imaging

MARCH 21, 2025

Circulation: Cardiovascular Imaging, Ahead of Print.

Pulmonary 40

Pulmonary Cardiovascular Imaging Circulation 40

Journal of the American Heart Association

MARCH 7, 2025

BackgroundLifethreatening pulmonary arterial hypertension (PAH) still lacks a direct therapeutic approach targeted to the molecular defects associated with the disease. Journal of the American Heart Association, Ahead of Print. No effect of rimeporide was detected in control rats.

Pulmonary 45

Pulmonary Hypertension Circulation 45

Circulation

JUNE 9, 2024

Circulation, Volume 149, Issue 24 , Page e1412-e1412, June 11, 2024.

Pulmonary 45

Pulmonary Angioplasty Hypertension Circulation 45

Circulation

MAY 27, 2024

Circulation, Volume 149, Issue 22 , Page 1770-1774, May 28, 2024.

Pulmonary 45

Pulmonary Hypertension Circulation 45

Frontiers in Cardiovascular Medicine

APRIL 5, 2024

Inhaled NO has the unique ability to exert its vasodilatory effects in the pulmonary vasculature without any hypotensive side-effects in the systemic circulation. We will move on to the popular use of inhaled NO and will talk about the evidence base of the use of this selective pulmonary vasodilator.

Pediatrics 93

Pediatrics Pulmonary Biomarkers Innovation 93

Circulation: Cardiovascular Imaging

MARCH 13, 2025

Circulation: Cardiovascular Imaging, Ahead of Print. Very preterm-born young adults are at risk for developing pulmonary arterial (PA) hypertension later in life. BACKGROUND:Very preterm-born infants are at risk for developing bronchopulmonary dysplasia (BPD), a chronic lung disease. m/s [1.453.05] versus 1.61

Pulmonary 40

Pulmonary Hypertension Cardiovascular Imaging Circulation 40

Circulation: Cardiovascular Imaging

FEBRUARY 25, 2025

Circulation: Cardiovascular Imaging, Ahead of Print.

Pulmonary 40

Pulmonary Cardiovascular Imaging Hypertension Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146445-A4146445, November 12, 2024. Rationale:Previously we identified a mouse modelTie2Cre-mediated disruption ofEgln1of Pulmonary arterial hypertension (PAH) with progressive obliterative vascular remodeling including vascular occlusion and plexiform-like lesions and right heart failure.

Pulmonary 40

Pulmonary Hypertension Heart Failure Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4145487-A4145487, November 12, 2024. reported several cases in which right lower pulmonary vein (RLPV) thrombi extended into the left atrium (LA). Thrombi are difficult to visualize directly and are recognized as lacking in pulmonary vein blood flow. This study had two limitations.

Pulmonary 40

Pulmonary Diabetes Atherosclerosis Heart Disease 40

Hypertension Journal

DECEMBER 20, 2023

BACKGROUND:The pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) is multifactorial and growing evidence has indicated that hematological disorders are involved. Hypertension, Ahead of Print. of patients with CTEPH are associated with a severe inflammatory state and confer a poorer prognosis in long-term follow-up.

Hypertension 49

Hypertension Pulmonary Cardiovascular Disease Circulation 49

Circulation

FEBRUARY 5, 2024

Circulation, Ahead of Print. Small hairpin RNA and ME1 enzymatic inhibitor (ME1*) were used to study the mechanism of ME1 in pulmonary artery endothelial cells. Endothelial-specificME1deletion similarly attenuated pulmonary vascular remodeling and PH development in mice, suggesting a critical role of endothelial ME1 in PH.

Pulmonary 45

Pulmonary Hypertension Pharmacology Circulation 45

Circulation: Cardiovascular Interventions

DECEMBER 27, 2024

Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Varying rates of nonsustained ventricular tachycardia (NSVT) have been reported early after transcatheter pulmonary valve replacement (TPVR) with the Harmony valve, but data regarding rhythm outcomes beyond hospital discharge are limited.

Pulmonary 40

Pulmonary Arrhythmia Cardiovascular Interventions Tachycardia 40

Frontiers in Cardiovascular Medicine

FEBRUARY 28, 2024

Background Pulmonary artery (PA) strain is associated with structural and functional alterations of the vessel and is an independent predictor of cardiovascular events. Circulating metabolites were measured by cross-sectional targeted metabolomics analysis. Results Among n  = 170 adults (mean age 71 ± 6.3

Pulmonary 49

Pulmonary Risk Factors Cardiovascular Disease Circulation 49

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4140751-A4140751, November 12, 2024. this clinical case, we discussed sub-massive pulmonary embolism (PE) complicated by a right heart clot-in-transit presenting insidiously. On arrival, his troponins were elevated 373, elevated BNP 934.

Embolism 40

Embolism Pulmonary Ultrasound ICU 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4122350-A4122350, November 12, 2024. Pulmonary vein thrombi (PVTs) are common and are underestimated. Background:Retrieved thrombus studies have shown that retrieved thrombi have calcifications, indicating that the thrombi are old. In 2022, we reported that 98.6% from 50 y.o. from 50 y.o.

Pulmonary 45

Pulmonary Diabetes Atrial Fibrillation Hypertension 45

MIBHS

OCTOBER 31, 2024

Chronic Pulmonary Disease Lung diseases like chronic obstructive pulmonary disease (COPD) can lead to pulmonary hypertension, which in turn can cause the right side of the heart to enlarge, a condition known as cor pulmonale. Regular physical activity can strengthen the heart and improve circulation.

Blood Pressure 52

Blood Pressure Blood Clot Heart Valves Heart Rhythm 52

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4141118-A4141118, November 12, 2024. Metabolic abnormalities play a crucial role in the pathophysiological process of pulmonary vascular remodeling. ng/ml; idiopathic pulmonary arterial hypertension group: 5.28 ± 0.77

Pulmonary 40

Pulmonary Hypertension Heart Failure Circulation 40

All About Cardiovascular System and Disorders

MARCH 30, 2024

As the aorta is small in hypoplastic left heart syndrome, proximal portion of the pulmonary artery is taken and along with the valve, it is used to reconstruct the proximal aorta, this region, and it is connected to the right ventricle. So right ventricle maintains both systemic and pulmonary circulation after a Norwood procedure.

Aortic valve 52

Aortic valve Pulmonary Congenital Heart Disease Bicuspid/Mitral 52

Circulation: Cardiovascular Imaging

DECEMBER 16, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 12 , Page e016882, December 1, 2024. BACKGROUND:Right ventricular-arterial coupling (RVAC) describes the relationship between right ventricular contractility and pulmonary vascular afterload.

Pediatrics 40

Pediatrics Pulmonary Hypertension Congenital Heart Disease 40