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Circulation: Heart Failure, Volume 16, Issue 11 , Page e010802, November 1, 2023. Heart failure with preservedejectionfraction (HFpEF) has become the leading form of heart failure worldwide, particularly among elderly patient populations.
Circulation, Ahead of Print. Background:Patients with heart failure (HF) with preservedejectionfraction (HFpEF) and obesity experience high burden of symptoms and functional impairment, and a poor quality of life. In the STEP-HFpEF trial, once-weekly semaglutide 2.4 5.4,16.1), 8.1 2.7,13.4), 4.6 (-0.6,9.9)
Circulation, Ahead of Print. Background: Patients with heart failure, a preservedejectionfraction (HFpEF), and obesity have significant disability and suffer frequent exacerbations of heart failure. The broad spectrum of effects was reflected in benefits on the hierarchical composite (win ratio 1.63, 95%CI, 1.17, 2.28;P=0.004).Conclusions:
Circulation: Heart Failure, Ahead of Print. BACKGROUND:In heart failure, sympathetic excess and exercise intolerance impair quality of life. In heart failure with reduced ejectionfraction, exercise stimulates a reflex increase in muscle sympathetic nerve activity (MSNA) that relates inversely to peak oxygen uptake (VO2peak).
Circulation, Volume 150, Issue Suppl_1 , Page A4118122-A4118122, November 12, 2024. The primary outcomes were exercise capacity, diastolic function, and quality of life at baseline evaluation. Patients were divided into two groups based on BB use at trial enrollment.
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