Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4144040-A4144040, November 12, 2024. The sections were also used for immunohistochemistry with cell marker antibodies (to measure % plaque smooth muscle cells (SMC), macrophages (MF), and endothelial cells (EC)). to D: 30.7%), elevation in plaque MF (A: 16.7%

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Plaque Atherosclerosis Heart Disease Circulation 40

Dr. Paddy Barrett

FEBRUARY 27, 2024

The reason: They were accumulating plaque in their coronary arteries much earlier than their peers. You can’t have a heart attack if you don’t have plaque in your coronary arteries. And plaque in your coronary arteries is the result of exposure to risk factors over time. The answer: Risk Factors. The answer.

Risk Factors 111

Risk Factors Heart Disease Heart Attack Heart attacks 111

Dr. Smith's ECG Blog

MAY 19, 2020

If the arrest was caused by acute MI due to plaque rupture, then the diagnosis is MINOCA. Here is my comment on MINOCA: "Non-obstructive coronary disease" does not necessarily imply "no plaque rupture with thrombus." They often cannot even be recognized as culprits, as fissured or ulcerated plaque. FFR can be useful.

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Defibrillator Circulation Plaque Cardiac Arrest 52

Stroke Journal

FEBRUARY 1, 2024

Introduction:A new Plaque-RADS classification (I-IV) is proposed to categorize the degree of carotid plaque instability and risk of embolic ischemic stroke. Carotid total plaque thickness and ulceration were scored by a neuroradiologist blinded to stroke side. N=188 plaques) met criteria.

Plaque 40

Plaque Embolism Stroke Strokes 40

Circulation: Cardiovascular Imaging

JANUARY 11, 2024

Circulation: Cardiovascular Imaging, Ahead of Print. A decrease in the percentage of unstable core (fibro-fatty+necrotic plaque; from 14.1 [7.9–22.3] BACKGROUND:Intensive lipid-lowering therapy may induce coronary atherosclerosis regression. The global coronary PB changed from 34.6% (32.5%–36.8%) 36.8%) at entry to 30.4% (27.4%–33.4%)

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Plaque Atherosclerosis Cardiovascular Imaging Cardiovascular Disease 40

Dr. Smith's ECG Blog

NOVEMBER 15, 2023

MINOCA may be due to: coronary spasm, coronary microvascular dysfunction, plaque disruption, spontaneous coronary thrombosis/emboli , and coronary dissection; myocardial disorders, including myocarditis, takotsubo cardiomyopathy, and other cardiomyopathies. Circulation [Internet] 2017;135(16):1481–9. Circulation. From Gue at al.

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Coronary Angiogram Plaque Thrombosis STEMI 110

Ken Grauer, MD

FEBRUARY 3, 2024

Non-obstructive coronary disease at the time cardiac cath is done does not necessarily imply there was no plaque rupture with thrombus. These plaques will often not be recognized as "culprits" — because no fissuring or ulceration is seen.

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Blog Cardiac Arrest STEMI Plaque 163

Circulation: Cardiovascular Imaging

JULY 15, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 7 , Page e017135, July 1, 2024.

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Plaque Cardiovascular Imaging Circulation 40

CTVS

SEPTEMBER 17, 2024

PAD is a serious condition affecting circulation and blood vessels, causing them to narrow from plaque buildup in the arteries and blocking blood flow to the extremities, typically the legs and feet. It is estimated that more than 10 million Americans are living with PAD, or Peripheral Artery Disease.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Plaque Atherosclerosis Cholesterol 52

CTVS

MAY 29, 2024

PAD occurs when plaque builds up in the arteries and limits blood flow to the lower extremities. This limited blood flow causes poor circulation, which if left un-treated, can severely damage foot and leg tissue, sometimes resulting in non-healing ulcers.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Plaque Circulation 52

MIBHS

FEBRUARY 28, 2025

Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries. Exercise: Regular physical activity strengthens the heart and improves blood circulation. Cardiomyopathies: These diseases affect the heart muscle, impairing its ability to pump blood effectively.

Genetic predisposition 52

Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Dr. Paddy Barrett

SEPTEMBER 20, 2024

When we say heart disease, what we really mean is plaque in the artery wall. Therefore, the number of ApoB particles is a direct measure of the number of circulating cholesterol particles in your bloodstream. You just need to know how. This Is Known As Atherosclerosis. We also refer to these cholesterol particles as ApoB particles.

Heart Disease 111

Heart Disease Cholesterol Atherosclerosis Heart Attack 111

Circulation: Cardiovascular Imaging

NOVEMBER 18, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 11 , Page e017613, November 1, 2024.

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Cardiovascular Imaging Plaque Circulation 40

Circulation: Cardiovascular Imaging

JANUARY 10, 2024

Circulation: Cardiovascular Imaging, Ahead of Print.

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Plaque Cardiovascular Imaging Circulation 40

DAIC

FEBRUARY 3, 2025

Lp(a) is emerging as an important, yet under-recognized, potential risk factor for cardiovascular disease due to its ability to promote the development of plaques within artery walls, clot formation and aortic valve calcification. Circulation. Arnett DK et al. 2019 Sep 10;140(11):e563-e595. doi: 10.1161/CIR.0000000000000677.

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Cardiovascular Disease Aortic valve Biomarkers Innovation 52

Circulation: Cardiovascular Imaging

MARCH 12, 2024

Circulation: Cardiovascular Imaging, Ahead of Print.

Cardiovascular Imaging 40

Cardiovascular Imaging Plaque Circulation 40

Dr. Paddy Barrett

JANUARY 23, 2024

However, most adults will start to develop advanced plaque in their coronary arteries early in life. By age 66, more than half of all females will have evidence of advanced plaque in their coronary arteries, as seen on a CT calcium score. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque.

Heart Disease 105

Heart Disease Blood Pressure Dementia Atherosclerosis 105

Physiologically Speaking

APRIL 10, 2024

people from the general population), coronary artery calcium scores (CACS) are higher, indicating more calcification and the presence of atherosclerotic plaques. Calcified plaques are known to be more stable and less prone to rupture and lead to a heart attack. When comparing athletes to control groups (i.e., hours per week).

Atherosclerosis 52

Atherosclerosis Plaque Exercise Cardiovascular Disease 52

Circulation

FEBRUARY 13, 2024

Circulation, Ahead of Print. Sections of coronary atherosclerotic plaques from donors were immunostained to analyze calcium deposition and 4-HNE. Vascular calcification is associated with increased cardiovascular adverse events.

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Coronary Artery Disease Kidney Disease Aortic Plaque 80

DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 7 Research has shown inflammation plays a significant role in the development of atherosclerosis and ASCVD,8-10 and even the formation of plaque.11 Circulation.

Cardiovascular Disease 111

Cardiovascular Disease Heart Attack Heart attacks Coronary Artery Disease 111

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142898-A4142898, November 12, 2024. The primary outcome was the prevalence of carotid artery plaques assessed by ultrasound. Secondary outcomes included changes in NMR-derived lipoprotein subclasses and their mediation effects on carotid plaque. day) or low-dose (1.5g/day)

Atherosclerosis 40

Atherosclerosis Diabetes Plaque Cholesterol 40

Stroke Journal

FEBRUARY 1, 2024

Atherosclerotic plaque formation is modulated by genetic and environmental interactions. In this study, we examined the effects of ApoE deficiency and high fat diet (HFD) on plaque formation and immunomodulatory cellular and molecular mechanisms in mice models.Methods:Wild type and ApoE knockout (KO) mice were fed with normal or HFD.

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Atherosclerosis Risk Factors Diet Plaque 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4140066-A4140066, November 12, 2024. The incidence of no-reflow was higher in patients with attenuated plaque ≥5 mm in length as evaluated by intravascular ultrasound (IVUS).Objective:The Blood pressure decrease during PCI was significantly more pronounced in the no-reflow group (47.4%

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Ultrasound Plaque Blood Pressure Myocardial Infarction 40

Circulation

DECEMBER 17, 2024

Circulation, Ahead of Print. BACKGROUND:Mitochondrial dysfunction is a key factor in the development of atherogenesis. METTL4 (methyltransferase-like protein 4) mediates N6- methyldeoxyadenosine (6mA) of mammalian mitochondrial DNA (mtDNA). However, the role of METTL4-mediated mitoepigenetic regulation in atherosclerosis is still unknown.

Atherosclerosis 40

Atherosclerosis Transplant Plaque Pharmacology 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4132968-A4132968, November 12, 2024. M-MDSCs phenotype switch, atherosclerotic lesion development and plaque phenotype was studiedin vivo.Results:We observed CCR5 elevation on Monocytic-MDSCs in the early phase of atherosclerosis. 3ng/day for 15 days).M-MDSCs

Atherosclerosis 40

Atherosclerosis Plaque Coronary Artery Disease Diet 40

Circulation: Genomic and Precision Medicine

NOVEMBER 28, 2023

Circulation: Genomic and Precision Medicine, Ahead of Print. 10−4, we identified 3 genes (ATP1B1,ARVCF, andLIPG) associated with CAC and 2 genes (ABCG8andEIF2B2) associated with carotid intima-media thickness and carotid plaque, respectively, through gene-based rare variant set analysis.

Atherosclerosis 40

Atherosclerosis Diabetes Plaque Coronary Artery Disease 40

DAIC

MAY 8, 2024

Circulation, vol. It provides anatomic data, plaque identification and characterization, as well as the calculations of FFR CT , a coronary physiological simulation, computed from simulated pressure, velocity and blood flow information obtained from a 3D computer model generated from static coronary CT images. The Lancet, vol.

Coronary Artery Disease 111

Coronary Artery Disease Chest Pain Ischemia Myocardial Infarction 111

Stroke Journal

OCTOBER 31, 2024

Circulating immune cells have been found to induce immunothrombosis, and they actively participate in the formation of the thrombus by promoting platelet recruitment and thrombin activation. Additionally, the formation of thromboinflammation leads to increased instability of atherosclerotic plaques.

Stroke 40

Stroke Strokes Thrombosis Plaque 40

Circulation

FEBRUARY 9, 2025

Circulation, Volume 151, Issue 6 , Page 400-415, February 11, 2025. Lp(a) can enter the vessel wall, leading to the accumulation of oxidized phospholipids in the arterial intima, which are crucial for initiating plaque inflammation and triggering vascular disease progression.

Pharmacology 49

Pharmacology Cardiovascular Disease Plaque Risk Factors 49

Dr. S. Venkatesan MD

FEBRUARY 25, 2024

However ,we have some effective clinical and pathological markers too, for effective re-vascularisation They are clinical well being and good functional capacity , relief from chest-pain, reduction of plaque volume, plaque stabilisation, maintenance of collaterals , microvascular patency , reduction of recurrent events.

Chest Pain 59

Chest Pain Plaque Stents Stent 59

Circulation

JANUARY 15, 2024

Circulation, Volume 149, Issue 3 , Page 251-266, January 16, 2024. Nevertheless, the relationship between CAC and the susceptibility of a plaque to provoke a thrombotic event remains incompletely understood. Coronary artery calcification (CAC) accompanies the development of advanced atherosclerosis.

Coronary Artery Disease 45

Coronary Artery Disease Atherosclerosis Laboratory Plaque 45

MIBHS

OCTOBER 31, 2024

Coronary Artery Disease (CAD) CAD, which involves the narrowing or blockage of coronary arteries due to plaque buildup, can reduce blood flow to the heart. Regular physical activity can strengthen the heart and improve circulation. Avoid smoking and limit alcohol intake. Monitor blood pressure and cholesterol levels regularly.

Blood Pressure 52

Blood Pressure Blood Clot Heart Valves Heart Rhythm 52

Dr. Smith's ECG Blog

JUNE 23, 2024

They shocked him twice before return of spontaneous circulation. His ECG at the accepting facility is shown below: Accepting facility ECG The team reviewed his angiography films with an interventionalist and thought they were suspicious for plaque rupture in LAD, but they were not confident.

Chest Pain 120

Chest Pain Cardiac Arrest Sudden Cardiac Death Blog 120

Circulation

NOVEMBER 8, 2023

Circulation, Volume 148, Issue 24 , Page 1958-1973, December 12, 2023. Parabiosis studies revealed that monocyte-derived macrophages were significantly increased in the hearts of PCOS mice because of enhanced circulating Ly6C+monocyte supply. BACKGROUND:Reducing cardiovascular disease burden among women remains challenging.

Coronary Artery Disease 40

Coronary Artery Disease Myocardial Infarction Circulation Plaque 40

Dr. Smith's ECG Blog

NOVEMBER 30, 2022

To prove there is no plaque rupture, you need to do intravascular ultrasound (IVUS). An angiogram is a "lumenogram;" most plaque is EXTRALUMINAL!! One of the most common is rupture of a non-obstructive plaque, with thrombus formation and OMI that spontaneously lyses and leaves a wide open artery. It can only be seen by IVUS.

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Plaque Chest Pain Thrombosis Stenosis 52

Dr. Smith's ECG Blog

DECEMBER 7, 2023

Circulation: Cardiovascular Interventions , 7(5), 645–655. Learning Points: Type 1 MI is the type we are most familiar with: rupture of atherosclerotic plaque with production thrombus or platelet fibrin aggregates. Buller, C. Starovoytov, A., Robinson, S., Vuurmans, T., Humphries, K., & & Mancini, G.

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SCAD Ischemia Coronary Artery Disease Cardiomyopathy 126

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142716-A4142716, November 12, 2024. Background:Heavily calcified coronary bifurcation lesions present significant challenges during percutaneous coronary intervention, particularly during atherectomy due to the risk of side branch occlusion from plaque shift.

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Coronary Angiogram Stenosis Plaque Stents 40