Remove Circulation Remove Physiology Remove Pulmonary
article thumbnail

Is the Heart Really a Pump? New Perspectives on Cardiovascular Physiology

Physiologically Speaking

Cardiovascular physiology has long held that the heart is a mechanical pump and that the heart’s propulsive power is the main driver of blood flow throughout the body. However, the cardiocentric view of circulation fails to explain blood flow regulation during exercise and other unique scenarios.

article thumbnail

Characterizing the Causal Pathway From Childhood Adiposity to Right Heart Physiology and Pulmonary Circulation Using Lifecourse Mendelian Randomization

Journal of the American Heart Association

This approach allowed us to evaluate the effect of childhood body size on 11 measures of right heart and pulmonary circulation independent of other anthropometric traits at various stages in the lifecourse. 0.33];P=3×10−7) independent of adulthood body size.

article thumbnail

Physiology Friday #205: What Limits VO2 Max? It Might Depend on Your Fitness Level.

Physiologically Speaking

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. There’s a long-running debate in exercise physiology about what limits VO2 max. Physiology is integrative, not isolated. To receive new posts and support my work, consider becoming a free or paid subscriber.

article thumbnail

Transcatheter Palliation With Pulmonary Artery Flow Restrictors in Neonates With Congenital Heart Disease: Feasibility, Outcomes, and Comparison With a Historical Hybrid Stage 1 Cohort

Circulation: Cardiovascular Interventions

Circulation: Cardiovascular Interventions, Ahead of Print. Background:Neonates with complex congenital heart disease and pulmonary overcirculation have been historically treated surgically. 3.3]) underwent a PFR procedure; 15 (88%) had single ventricle physiology; 15 (88%) were high-risk surgical candidates. kilograms [IQR, 2.1–3.3])

article thumbnail

Arterial Switch Operation

All About Cardiovascular System and Disorders

That is, right ventricle is connecting to aorta, and left ventricle to pulmonary artery. That is, pulmonary artery is transposed over to the right ventricle, and aorta over to the left ventricle, so that normal anatomy is restored. In dextro transposition of great arteries or D-TGA, there is ventriculoarterial discordance.

article thumbnail

Abstract 4123391: CardioMEMS and Mavacamten: A Synergistic Approach in Managing Hypertrophic Obstructive Cardiomyopathy with HFpEF Phenotype

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page A4123391-A4123391, November 12, 2024. The CardioMEMS PA (pulmonary artery) sensor allows remote pulmonary artery diastolic (PAD) pressure monitoring to adjust diuresis in heart failure with preserved ejection fraction (HFpEF).

article thumbnail

Abstract 4143844: Multidisciplinary management of a pregnant patient with advanced systolic heart failure

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page A4143844-A4143844, November 12, 2024. However, stabilization was expected to be temporary due to ongoing physiologic changes of pregnancy.