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Circulation, Ahead of Print. There is increasing recognition that nearly all cancer treatments pose some short- or long-term risk for development of cardiovascular disease and that pediatric patients with cancer may be especially vulnerable to cardiovascular disease because of young age at treatment and expected long life span afterward.
The impact of chest compression (CC) pause duration on survival outcomes in pediatric in-hospital cardiac arrests remains unclear, despite the American Heart Association’s recommendation to limit pauses to less than 10 seconds for children without solid evidence. Circulation 2024; 149: 1493-1500.
tim.hodson Mon, 03/17/2025 - 14:56 March 17, 2025 Being born with a heart defect may be associated with an increased cancer risk for babies and their moms, according to new research published today in the American Heart Associations flagship journal Circulation. are forms of congenital heart defects (CHD).
Addressing an Unmet Need in Pediatric Patients with HeFH Heterozygous familial hypercholesterolemia (HeFH) affects about 1 in 313 people—characterized by dangerously high low-density lipoprotein cholesterol (LDL-C) levels. Detecting and treating it early in pediatric patients can prevent heart problems later.
Circulation, Ahead of Print. Pediatric practice varies widely, likely because aortopathy is pathogenically heterogeneous, including genetic and nongenetic conditions, and there is limited published evidence to guide care in children. The most common causes of pediatric aortopathy are reviewed.
Circulation, Volume 150, Issue Suppl_1 , Page A4143624-A4143624, November 12, 2024. Current pediatric DKA management guidelines should include routine 12-lead ECGs and venous blood gas analyses with electrolytes to monitor QTc changes and mitigate arrhythmia risks. The Rautaharju formula provides a more accurate correction.
Despite this, evidence-based treatment and prevention guidelines of pediatric AIS remain insufficient. Direct oral anticoagulants (DOACs) are approved in many countries for the treatment and prevention of pediatric venous thrombosis but its use in pediatric arterial thrombosis is less established.
BACKGROUND:Inflammatory type focal cerebral arteriopathy (FCA-i) in the anterior circulation (AC) is well characterized, and the focal cerebral arteriopathy severity score (FCASS) reflects the severity of the disease. interquartile range, 2.7–8.2 15.6]; 20 male; 57.1%) years with FCA-i were identified. The total incidence rate was 0.15/100
Stroke patients suffered from a perinatal (n = 8) or pediatric (n = 9) stroke - confirmed with brain MRI - affecting various vascular territories of the anterior and posterior circulations. The task required searching for on-screen targets with increasing visual complexity.
Circulation, Ahead of Print. BACKGROUND:Homozygous familial hypercholesterolemia (HoFH) is a rare genetic disorder characterized by severely elevated low-density lipoprotein cholesterol (LDL-C) levels due to profoundly defective LDLR (LDL receptor) function.
Does hospital median cardiopulmonary resuscitation (CPR) duration in patients without return of circulation (ROC) predict survival among hospitalized children?
Inhaled nitric oxide (NO) has been used in pediatric and adult perioperative cardiac intensive care for over three decades. Inhaled NO has the unique ability to exert its vasodilatory effects in the pulmonary vasculature without any hypotensive side-effects in the systemic circulation.
Circulation, Volume 150, Issue Suppl_1 , Page A4139192-A4139192, November 12, 2024. Background:Asynchronous remote patient monitoring (RPM) is increasingly common in healthcare models for infants with congenital heart disease (CHD). HCTs reported improved communication (4.5+.77) 77) and clinical decision-making with video reviews (4.47+.79).
Here, we compare the CBF, CVR, and ATT in pediatric Moyamoya patients before and after bypass using multi-delay ASL.Hypothesis:CVR will increase significantly after bypass surgeries.Methods:Imaging data were acquired from 22 Moyamoya patients (11 months - 18 years, 14 females) using a 3T MRI system.
Circulation: Arrhythmia and Electrophysiology, Ahead of Print. Using retrospective ECG data from 1819 pediatric patients at Childrens National Hospital and 2400 subjects from the Pediatric Heart Network database, alongside in vivo (n=55) and ex vivo (n=66) guinea pig ECG recordings, we evaluated the formulas effectiveness.
Circulation, Volume 150, Issue Suppl_1 , Page A4144727-A4144727, November 12, 2024. Introduction:Dilated cardiomyopathy (DCM) is a common cardiomyopathy characterized by ventricular dilatation and systolic dysfunction.
Circulation, Volume 150, Issue Suppl_1 , Page A4134590-A4134590, November 12, 2024. Conclusion:Cardiac catheterization is a safe procedure in pediatric patients with cardiomyopathy, with an overall MAE rate of 1.6%. We aim to describe the rate of MAE in children with cardiomyopathy undergoing cardiac catheterization.
BACKGROUNDMoyamoya is a rare arteriopathy affecting the intracranial circulation with a risk of stroke in the pediatric population. Referral to high‐volume centers for pediatric moyamoya revascularization provides both improved outcomes for the patients and substantial cost savings for the insurers.
Objective:This study aims to evaluate the risk of cerebrovascular events in pediatric MMD during the preoperative waiting period, and explore the related risk factors and appropriate operation opportunities.Methods:This study is an observational cohort study, including 736 children with MMD from their initial visit until the completion of surgery.
Introduction:Moyamoya is a progressive steno-occlusive cerebrovascular arteriopathy of bilateral anterior circulation. Twenty-three (34%) children had complete occlusion of bilateral anterior circulation without asymmetry at diagnosis. This left-sided predilection was statistically significant (p=0.03).
Circulation: Heart Failure, Volume 16, Issue 12 , Page e010351, December 1, 2023. BACKGROUND:PRDM16 plays a role in myocardial development through TGF-β (transforming growth factor-beta) signaling.
Circulation, Ahead of Print. Environmental toxicants and pollutants are causes of adverse health consequences, including well-established associations between environmental exposures and cardiovascular diseases.
so it must be a pediatric ECG. This is typical of pediatric ECGs because the fetal circulation depends on the right ventricle. What can you say about this ECG at a rate of 230 beats per minute? Answer below The QRS is very narrow (about 70 ms?), Thus, what appear to be p-waves are indeed p-waves (see leads II and V1).
Circulation, Ahead of Print. BACKGROUND:Much of our knowledge of organ rejection after transplantation is derived from rodent models.METHODS:We used single-nucleus RNA sequencing to investigate the inflammatory myocardial microenvironment in human pediatric cardiac allografts at different stages after transplantation.
Circulation, Ahead of Print. Secondary outcomes were sustained return of spontaneous circulation (ROSC), survival to discharge with favorable neurologic outcome, and new morbidity among survivors. The primary outcome was survival to hospital discharge. time to CPR start; chest compression rate, depth, and fraction; ventilation rate).Results:Among
Circulation, Ahead of Print. Wearable biosensors (wearables) enable continual, noninvasive physiologic and behavioral monitoring at home for those with pediatric or congenital heart disease. Wearables allow patients to access their personal data and monitor their health.
Circulation, Ahead of Print. Chronic heart failure is increasingly being recognized as a major contributor to ongoing morbidity and mortality in this population as it ages, and treatment strategies to prevent and treat heart failure in the pediatric population are needed.
Hypertension was defined according to the 2020 International Society of Hypertension Guidelines (adults) and 2017 American Academy of Pediatrics Guidelines (children). Preoperatively, 146 adult and 20 pediatric patients met the diagnostic criteria for hypertension resulting in prevalences of 60.3% respectively. months in adults (33.8±14.9
Circulation, Volume 150, Issue Suppl_1 , Page A4146655-A4146655, November 12, 2024. Introduction:Ventricular septal defect (VSD) is the most common pediatric defect which benefits from closure at an early age. We included patients with body weights less than 30 lbs. months, mean weight of 17.87 ± 6.64
Circulation, Ahead of Print. This 2023 focused update to the neonatal resuscitation guidelines is based on 4 systematic reviews recently completed under the direction of the International Liaison Committee on Resuscitation Neonatal Life Support Task Force.
Circulation, Volume 150, Issue Suppl_1 , Page A4146002-A4146002, November 12, 2024. in the pediatric dataset and 5.6% This novel approach ensures high accuracy and enables real-time deployment in clinical settings.We in the adult dataset. Moreover, its efficiency was underscored by an impressive forward inference speed of up to 401.82
Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 452-461, October 1, 2023. The frequency of pathogenic variants was similar in pediatric (42.9%) and adult (43.6%) samples, but the distribution of mutated genes differed (P=8.30×10-4).
Circulation, Ahead of Print. In pediatric patients, left ventricular systolic dysfunction and pericardial effusion are the most common cardiovascular complications. Hematopoietic stem cell transplantation can cure various disorders but poses cardiovascular risks, especially for elderly patients and those with cardiovascular diseases.
Introduction:Moyamoya is a progressive cerebrovascular disease characterized by stenosis of the cerebral arteries in the anterior circulation and less often the posterior circulation. Stroke, Volume 55, Issue Suppl_1 , Page AWP222-AWP222, February 1, 2024. At time of diagnosis 16 children (67%) had basilar artery stenosis.
Circulation, Volume 150, Issue Suppl_1 , Page A4146022-A4146022, November 12, 2024. Background:Rarely, SARS-CoV-2 will lead to myocarditis associated with Multisystem Inflammatory Syndrome in Children (MIS-C). It remains unclear why MIS-C only targets specific children. of cases respectively.
Circulation, Volume 148, Issue 24 , Page e187-e280, December 12, 2023. The International Liaison Committee on Resuscitation engages in a continuous review of new, peer-reviewed, published cardiopulmonary resuscitation and first aid science.
Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Current metrics used to adjust for case mix complexity in congenital cardiac catheterization are becoming outdated due to the introduction of novel procedures, innovative technologies, and expanding patient subgroups.
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