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Methods We carried out a case-control study to identify circulating miRNAs associated with CHCM. We performed a clinical, echocardiographic, and laboratory evaluation and profiled circulating miRNA in the serum samples. Results Differences between groups were observed in clinical variables and in the analysis of miRNAs.
What are the safety, utility, and prognostic implications of invasive implanted hemodynamic monitoring (IHM) using the CardioMEMS™ HF System (Abbott Laboratories, Abbott Park, Illinois) in patients with Fontan circulation (FC)?
Material and methods This is a retrospective analysis of the patients with OHCA and return of spontaneous circulation (ROSC) in the community who attended the cardiac catheter laboratory in a DGH between 1 September 2021 and 25 September 2023. The study aims to validate the MIRACLE2 score in a district general hospital (DGH).
Circulation, Volume 150, Issue Suppl_1 , Page A4141868-A4141868, November 12, 2024. Inflammatory responses result from coordinated actions of circulating molecular mediators and circulating immune cells (CIC). Introduction:Inflammation is pivotal in initiating and accelerating atherosclerotic cardiovascular disease (ASCVD).
Circulation, Ahead of Print. Despite insufficient evidence to support direct-to-consumer genetic testing in routine clinical care, cardiovascular clinicians increasingly face questions about its utility and interpretation because individuals can purchase these tests directly from laboratories.
Background:The effect of renal dysfunction on early infarct growth rate (IGR) in anterior circulation large vessel occlusion (ACLVO) stroke is not well studied. Renal dysfunction was assessed based on serum creatinine and estimated glomerular filtration rate (eGFR) on presenting laboratories. mL/min/1.73m2, p < 0.05).
By using molar units, laboratory professionals and clinicians know the Lp(a) measurements reflect the number of particles rather than any difference in the size of the particles. "We Circulation. Arnett DK et al. 2019 Sep 10;140(11):e563-e595. doi: 10.1161/CIR.0000000000000677. 0000000000000677.
Purpose:Fast progressors (FP) of infarct growth in anterior circulation occlusions at 0-6 hours from onset (early window) have been associated with reduced rates of favorable outcome post endovascular thrombectomy (EVT). Stroke, Volume 56, Issue Suppl_1 , Page A70-A70, February 1, 2025.
most due to circulation issues. For patients at risk of amputation due to poor circulation, angioplasty procedures below the knee can be limb-saving. Rahul Patel and Robert Lookstein , and at the Advanced Vascular and Interventional Services office-base laboratory in West Orange, New Jersey by Drs.
Circulation: Cardiovascular Interventions, Ahead of Print. In this review, we summarize recent advances in radiation protection in the cardiac catheterization laboratory and discuss the effectiveness of traditional and novel radiation protection strategies and equipment.
Pictured Left to Right: Members and students of the McGill Gene Editing Laboratory at The Texas Heart Institute in Houston, Texas: Fansen Meng, PhD, Xiao Li, PhD, James Martin, MD, PhD, Rich Li, PhD (back), Maggie Lim (undergraduate student at Rice University front), Yuka Morikawa, PhD, Ann Bromley.
Circulation, Volume 150, Issue Suppl_1 , Page A4148010-A4148010, November 12, 2024. Laboratory values including BNP, CRP, D-dimer, ferritin, fibrinogen, lactate and troponin were analyzed for correlation with echo findings.Results:TAPSE was significantly lower in deceased patients (1.9± 0.4cm vs 1.3±0.6 cm, P< 0.05).
Circulation, Volume 150, Issue Suppl_1 , Page A4121816-A4121816, November 12, 2024. Laboratory workup notable for markedly elevated high-sensitivity troponin to 3398 ng/L, and elevated CRP. To date, only 16 cases of cardiac involvement in IgA vasculitis have been reported.
Circulation, Volume 149, Issue 3 , Page 251-266, January 16, 2024. It outlines the pathophysiology of CAC and reviews laboratory, histopathological, and genetic studies, as well as imaging findings, to characterize different types of calcification and to elucidate their implications.
Heparin, the most utilized anticoagulant, carries concerns for heparin-induced thrombocytopenia and possible resistance given its dependence on co-factors and circulating proteins to exert its pharmacologic effect. Moreover, this review suggests that bivalirudin utilization presents the opportunity for ECMO management simplification.
Circulation: Cardiovascular Interventions, Ahead of Print. Currently, measurement of relative pulmonary perfusion can only be performed outside the catheterization laboratory. BACKGROUND:Maldistribution of pulmonary blood flow in patients with congenital heart disease impacts exertional performance and pulmonary artery growth.
Conducted in the UK, the study enrolled 862 patients aged 18 or older who experienced return of spontaneous circulation after cardiac arrest without ST elevation.
Circulation, Volume 150, Issue Suppl_1 , Page A4147331-A4147331, November 12, 2024. Single cell sequencing was performed on circulating immune cells. database from Ma’ayan laboratory at Icahn School of Medicine. 1.98, 80% male, screening SBP/DBP was 137.3±4/88.2±2.9). Pearson correlation was used to analyze the associations.
Circulation, Volume 150, Issue Suppl_1 , Page A4135466-A4135466, November 12, 2024. Background:Percutaneous coronary intervention (PCI) is a treatment that requires attention in terms of infection control, as it necessitates aseptic procedures similar to surgical operations.
Circulation: Cardiovascular Interventions, Ahead of Print. BACKGROUND:Geographic stent-ostium mismatch is an important predictor of target lesion failure after percutaneous coronary intervention of an aorto-ostial right coronary artery lesion.
Circulation, Volume 150, Issue Suppl_1 , Page A4146022-A4146022, November 12, 2024. Background:Rarely, SARS-CoV-2 will lead to myocarditis associated with Multisystem Inflammatory Syndrome in Children (MIS-C). It remains unclear why MIS-C only targets specific children. of cases respectively.
Circulation, Ahead of Print. Background:Supported by laboratory and clinical investigations of adult cardiopulmonary arrest, resuscitation guidelines recommend monitoring end-tidal carbon dioxide (ETCO2) as an indicator of CPR quality but note that "specific values to guide therapy have not been established in children."Methods:This
Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. Clinical phenotypes, that is, pulmonary congestion or tissue hypoperfusion, were defined through a comprehensive assessment of clinical signs and symptoms, vital signs, and laboratory findings. female), 88.6%
Circulation, Volume 150, Issue Suppl_1 , Page ASu203-ASu203, November 12, 2024. Introduction:Previous studies have shown that ventilation during cardiopulmonary resuscitation (CPR) produces better patient outcomes. However, research regarding ventilation during the early stages of basic life support CPR is limited.
Circulation, Volume 150, Issue Suppl_1 , Page A4147019-A4147019, November 12, 2024. Blood samples were collected, and various laboratory parameters were measured at day-1, day-3, and day-7. The fractional excretion of sodium (FeNa) and FeUa were calculated.Results:The mean age of participants was 52.32 ± 14.04
Circulation, Volume 150, Issue Suppl_1 , Page A4145609-A4145609, November 12, 2024. Initial laboratory analysis was unremarkable. Introduction:Cannabis has been increasingly used as a recreational drug. Patient did not report any symptoms and was hemodynamically stable. He was euvolemic on physical exam.
Circulation, Volume 150, Issue Suppl_1 , Page A4146638-A4146638, November 12, 2024. Introduction/Background:According to the American Heart Association, the accumulation of plaque in the walls of arteries is identified as the primary cause of atherosclerotic cardiovascular disease (ASCVD).
Circulation, Volume 150, Issue Suppl_1 , Page A4145350-A4145350, November 12, 2024. Baseline patient demographics, insurance, pre-implant device data, and pre-implant laboratory data were also collected. The Distressed Communities Index (DCI), a validated measure of SES, was generated using home zip codes.
Circulation, Volume 150, Issue Suppl_1 , Page A4144351-A4144351, November 12, 2024. All of Us” is an 800,000 participant cohort that is followed longitudinally and collects demographics, adverse events, medications, procedures, and laboratory and clinical measurements.
Circulation, Volume 150, Issue Suppl_1 , Page A4137708-A4137708, November 12, 2024. Introduction:Intravenous hydration and contrast media volume reduction are the most important preventive factors against CI-AKI after PCI.
Edited by Bracey, Meyers, Grauer, and Smith A 50-something-year-old female with a history of an unknown personality disorder and alcohol use disorder arrived via EMS following cardiac arrest with return of spontaneous circulation. Circulation. Electrical alternans — was first observed in the laboratory by Herring in 1909.
Introduction:Several pre-hospital scales predict ischemic stroke due to large vessel occlusion; however, these scales often fail to detect atypical endovascular thrombectomy (EVT) cases, including posterior circulation and distal vessel occlusion. Imaging and laboratory data were not utilized in the ML process.
Data on demographics, clinical presentations, laboratory values, neuroimaging, and stroke metrics were collected. 12% of the cohort (n=34) had posterior circulation stroke. modified Rankin Scale (mRS) at one month, classified into good (mRS 2) and poor (mRS 5) outcomes was noted. DRAGON and MRI-DRAGON scores were calculated.
Circulation, Volume 150, Issue Suppl_1 , Page A4144918-A4144918, November 12, 2024. Echocardiography is performed within 24 hours and 3, 6, 12 months after MI.Results:The groups did not differ in major clinical parameters, comorbidities, medications, laboratory parameters, including hemoglobin level.
Circulation, Ahead of Print. severe prosthesis patient mismatch [PPM ] or moderate-severe aortic regurgitation [AR]) at 60 days as evaluated by Doppler-echocardiography and analyzed in a central echocardiography core laboratory. 3.28)%, and a median annulus diameter of 21.1 (IQR:
In general, for an APOB particle to be cleared from circulation, it attaches to an LDL receptor in the liver and is cleared from circulation. This results in higher circulating levels of LDL particles. APO E is also centrally involved in cholesterol metabolism. i.e. LDL-Cholesterol/APOB goes down.
Circulation, Ahead of Print. The cardiac catheterization laboratory plays an important role in the coordinated Chain of Survival for patients with out-of-hospital cardiac arrest. Out-of-hospital cardiac arrest is a leading cause of death, accounting for ≈50% of all cardiovascular deaths.
As an alternative therapeutic option, LVAD heart pumps have been implanted to help patients with end-stage heart failure sustain blood circulation in the body. Coulter Department of Biomedical Engineering and director of the Cardiovascular Fluid Mechanics Laboratory at Georgia Tech.
Circulation, Volume 150, Issue Suppl_1 , Page A4141052-A4141052, November 12, 2024. Laboratory tests showed markedly elevated troponin I levels (>50 ng/ml) and atrial fibrillation, along with inferior wall ST elevation on the electrocardiogram. The incidence of this dual infarction is currently unknown due to its rarity.
Circulation: Cardiovascular Imaging, Volume 17, Issue 2 , Page e016178, February 1, 2024. All images were analyzed at a core laboratory. BACKGROUND:It is not known whether there is a sex difference in the association between perivascular inflammation and plaque vulnerability.
Circulation, Volume 150, Issue Suppl_1 , Page A4139313-A4139313, November 12, 2024. We included patients registered in the Danish Heart Failure Registry who had laboratory data available to calculate FIB-4 scores from April 2003 to December 2019.
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