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Diffuse Subendocardial Ischemia on the ECG. Left main? 3-vessel disease? No!

Dr. Smith's ECG Blog

DISCUSSION: The 12-lead EKG EMS initially obtained for this patient showed severe ischemia, with profound "infero-lateral" ST depression and reciprocal ST elevation in lead aVR. The ECG cannot diagnose the etiology of ischemia; it only the presence of ischemia, from whatever etiology.

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Abstract 4119062: A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page A4119062-A4119062, November 12, 2024. Endothelial cell (EC) sensing of elevated fluid shear stress (FSS) from blood flow induces vessel outward remodeling to restore physiological FSS, but mechanisms are poorly understood.

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Are these Hyperacute T-waves?

Dr. Smith's ECG Blog

Incredibly , this case was just published in Circulation on January 22, 2018 (thanks to Brooks Walsh for finding this!) link] Circulation. Originally published January 22, 2018 Here is a case from Circulation year 2000 that was misdiagnosed as due to pancreatitis. Journal of Electrocardiology. 2012;45(1):15-17. 2010.12.162.

Article 52
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How can Warfarin be safe “even in” first trimester of pregnancy ? The story behind the 5 mg cut-off !

Dr. S. Venkatesan MD

It is interesting to note, while plasminogen levels are elevated, D-dimer is also increased, indicating an ongoing fight between pro & anticoagulant forces, converting the physiological maternal- placental bed a mini harmless DIC equivalent zone. The list is increasing in a steady fashion. What does it imply ?

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A young patient with diminishing pain with a subtle but diagnostic ECG.

Dr. Smith's ECG Blog

If you still have not read it, I strongly recommend that you read the following article on the diagnosis of "posterior" MI: Ischemic ST-Segment Depression Maximal in V1-V4 (Versus V5-V6) of Any Amplitude Is Specific for Occlusion Myocardial Infarction (Versus Nonocclusive Ischemia), by Meyers HP et al. Circulation 2002; 105(4): 539-42.

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HeartFlow Announces Revolutionary Five-Year Data Demonstrating a 63 Percent Mortality Reduction with FFRCT-Guided Care in PAD Patients

DAIC

6 This novel study marks a significant milestone in the field, evaluating the effectiveness of FFR CT in detecting ischemia-producing coronary stenosis in patients with severe PAD. Diagnosis and treatment of ischemia-producing coronary stenoses improves 5-year survival of patients undergoing major vascular surgery.” Circulation, vol.

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What kind of AV block is this? And why does she develop Ventricular Tachycardia?

Dr. Smith's ECG Blog

Extensive conduction system abnormalities can have various causes (ischemia, genetic, infectious, amyloid, etc). The physiologic reason for this — is thought to be the result of momentarily increased circulation from mechanical contraction arising from the "sandwiched in" QRS complex. The QRS complex in ECG #1 is wide.