MIBHS

OCTOBER 15, 2024

This is where coronary circulation comes into play. Coronary circulation refers to the movement of blood through the network of coronary arteries and veins that supply the heart muscle (myocardium) itself. Step-by-Step Breakdown of Coronary Circulation 1.

Circulation 52

Circulation Heart Attack Heart attacks Chest Pain 52

Dr. Smith's ECG Blog

JANUARY 2, 2016

There may be ischemia present, but it is not evident on the ECG. In this paper, Dr. Birnbaum writes: "In patients with ACS without LVH, ST depression with negative T waves in the lateral leads is a sign of sub-endocardial ischemia and is an independent predictor of adverse outcome [11 – 13].

Ischemia 52

Ischemia Chest Pain STEMI Myocardial Infarction 52

Stroke Journal

JANUARY 30, 2025

The significance of cranial bone marrow-derived leukocytes following ischemic stroke in the setting of ischemia/reperfusion remains uncertain. As a result, the exact percentages of cranial- and peripheral-derived neutrophils could easily be quantified and tracked, both in circulation and in the post-mortem brain.

Ischemia 40

Ischemia Circulation Stroke Strokes 40

Stroke Journal

JANUARY 30, 2025

Studying PMN recruitment and lifespan in ischemic stroke may offer insight into these failures in clinical trials and advance therapeutic development.Methods:PMNs were briefly pulse-labeled with 5-Ethynyl-2-deoxyuridine (EdU) to determine PMN lifespan and migration pattern following ischemia/reperfusion in stroke.

Ischemia 40

Ischemia Stroke Strokes Circulation 40

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionIntracranial atherosclerotic disease (ICAD) is associated with up to 32% of posterior circulation strokes.1 5 However, most of the existing literature focuses on anterior circulation. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.

Stents 40

Stents Stent Circulation Stroke 40

DAIC

MAY 8, 2024

6 This novel study marks a significant milestone in the field, evaluating the effectiveness of FFR CT in detecting ischemia-producing coronary stenosis in patients with severe PAD. Diagnosis and treatment of ischemia-producing coronary stenoses improves 5-year survival of patients undergoing major vascular surgery.” Circulation, vol.

Coronary Artery Disease 111

Coronary Artery Disease Chest Pain Ischemia Myocardial Infarction 111

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4147779-A4147779, November 12, 2024. Historically, DRP1 has been targeted through genetic downregulation and small-molecule inhibition, thereby mitigating apoptosis and lethal ischemia-reperfusion (IR).Aim:Our

Ischemia 40

Ischemia Circulation 40

Journal of the American Heart Association

FEBRUARY 14, 2024

RUPP offspring also had increased circulating B cells, cytolytic natural killer cells, and increased circulating AT1‐AA, which were normalized with maternal rituximab treatment. Maternal blood and tissues were collected. Immune cells were measured via flow cytometry, and AT1‐AA was quantified using a contraction bioassay.

Ischemia 40

Ischemia Blood Pressure Circulation Hypertension 40

Stroke Journal

FEBRUARY 1, 2024

Objective:Forward head posturing (FHP) has been associated with chronic anatomic vertebral artery disturbances possibly leading to posterior circulation ischemia. The data supporting FHP as a true risk factor of posterior circulation stroke has not been well established. There was a significant difference of 5.2

Risk Factors 40

Risk Factors Circulation Atrial Fibrillation Ischemia 40

Stroke Journal

JANUARY 4, 2024

These studies mainly concerned anterior circulation occlusions. All patients with a posterior circulation occlusion were included. Our results are in line with the literature on the anterior circulation. Primary outcome was a shift toward better functional outcome on the modified Rankin Scale at 90 days.

Thrombolysis 40

Thrombolysis Circulation Hemorrhage Ischemia 40

Circulation

APRIL 14, 2024

Circulation, Volume 149, Issue 16 , Page 1254-1257, April 16, 2024.

Quality of Life 49

Quality of Life Ischemia Circulation 49

Circulation: Cardiovascular Imaging

AUGUST 19, 2024

Circulation: Cardiovascular Imaging, Volume 17, Issue 8 , Page e017210, August 1, 2024.

Ischemia 40

Ischemia Cardiovascular Imaging Circulation 40

Circulation

NOVEMBER 13, 2024

Circulation, Ahead of Print. Advances in cardiovascular imaging have improved the ability to identify coronary artery stenosis in patients with KD, yet knowledge gaps remain regarding optimal frequency of serial imaging and the best imaging modality to identify those at risk for inducible myocardial ischemia.

Aneurysm 81

Aneurysm Myocardial Infarction Cardiovascular Imaging Ischemia 81

Circulation: Cardiovascular Quality & Outcomes

FEBRUARY 26, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print. BACKGROUND:The appropriate use criteria for revascularization of stable ischemic heart disease have not been evaluated using randomized data.

Ischemia 40

Ischemia Heart Disease Angina Anatomy 40

Circulation: Cardiovascular Interventions

NOVEMBER 6, 2023

Circulation: Cardiovascular Interventions, Ahead of Print. Background:Myocardial bridges (MBs) are prevalent and can be associated with acute and chronic ischemic syndromes.

Ischemia 40

Ischemia Exercise Angina Cardiovascular Interventions 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4113494-A4113494, November 12, 2024. To elucidate this relationship, we investigated gut microbiota dynamics in response to immunosuppression and cell therapy in a nonhuman primate (NHP) cardiac ischemia/reperfusion (IR) model, with controlled genetic, dietary, and environmental factors.

Ischemia 40

Ischemia Transplant Heart Transplant Biomarkers 40

Circulation: Cardiovascular Interventions

DECEMBER 28, 2023

Circulation: Cardiovascular Interventions, Ahead of Print.

Ischemia 40

Ischemia Cardiovascular Interventions Circulation 40

Dr. Smith's ECG Blog

NOVEMBER 19, 2016

DISCUSSION: The 12-lead EKG EMS initially obtained for this patient showed severe ischemia, with profound "infero-lateral" ST depression and reciprocal ST elevation in lead aVR. The ECG cannot diagnose the etiology of ischemia; it only the presence of ischemia, from whatever etiology. Circulation. Circulation 67, No.

Ischemia 40

Ischemia Cardiogenic Shock Aortic Stenosis 40

Circulation

FEBRUARY 19, 2024

Circulation, Volume 149, Issue 8 , Page 635-637, February 20, 2024.

Ischemia 53

Ischemia Circulation 53

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page ASu104-ASu104, November 12, 2024. Background:The incidence of cardiac arrest (CA) increases with age, leading to poorer neurological outcomes after the return of spontaneous circulation (ROSC) in the elderly.

Ischemia 40

Ischemia Cardiac Arrest Circulation Outcomes 40

Circulation: Cardiovascular Imaging

NOVEMBER 27, 2024

Circulation: Cardiovascular Imaging, Ahead of Print.

Ischemia 40

Ischemia Cardiovascular Imaging Bicuspid/Mitral Circulation 40

Circulation: Cardiovascular Quality & Outcomes

FEBRUARY 26, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

Ischemia 40

Ischemia Circulation Outcomes 40

Stroke Journal

FEBRUARY 1, 2024

We developed an ED triage diagnostic algorithm termed, “Dizzy-7”, based on evidence incorporating key history and physical examination elements derived in patients with acute posterior circulation ischemia.

Circulation 40

Circulation Stroke Strokes Ischemia 40

Journal of the American Heart Association

DECEMBER 24, 2024

Given the abnormalities in both pulmonary circulation and gas exchange caused by massive PE, venoarterial extracorporeal membrane oxygenation may be considered the preferred form of mechanical circulatory support for most patients.

Embolism 75

Embolism Pulmonary Ischemia Circulation 75

Stroke Journal

FEBRUARY 5, 2025

Growth Differentiation Factor 11 (GDF11), a member of the TGF- superfamily, is a circulating protein involved in cellular development and tissue repair. Background:Stroke remains a leading cause of death and disability, underscoring the urgent need for treatments that enhance recovery.

Ischemia 45

Ischemia Stroke Strokes Biomarkers 45

DAIC

FEBRUARY 14, 2025

Critical limb-threatening ischemia (CLTI) represents the end stage of peripheral artery disease (PAD), when poor circulation due to blockages in the arteries causes symptoms including numbness, sores that will not heal, gangrene, and extreme pain.

Peripheral Arterial Disease 52

Peripheral Arterial Disease Cancer Innovation Best Practices 52

Circulation

FEBRUARY 12, 2024

Circulation, Ahead of Print. The secondary outcomes included ischemia-driven target lesion revascularization, target vessel myocardial infarction, death, cardiac death, target vessel revascularization, stent thrombosis, and major adverse cardiac events. 1.19]; OCT versus ICA: OR, 0.87 [95% CI, 0.68–1.11];

Ultrasound 67

Ultrasound Myocardial Infarction Thrombosis Stents 67

Dr. Smith's ECG Blog

SEPTEMBER 29, 2024

This usually represents posterior OMI, but in tachycardia and especially after cardiac arrest, this could simply be demand ischemia, residual subendocardial ischemia due to the low flow state of the cardiac arrest. This rules out subendocardial ischemia and is diagnostic of posterior OMI. V4-5 continue to show STD.

Cardiac Arrest 110

Cardiac Arrest STEMI Ischemia SCAD 110

DAIC

MAY 16, 2024

If left untreated, PAD may progress to severe forms known as chronic limb-threatening ischemia (CLTI) and acute limb ischemia (ALI). It has been estimated that less than 5% of patients with PAD in the U.S. are prescribed to participate in a supervised exercise program.”

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Dr. Smith's ECG Blog

OCTOBER 23, 2023

Edited by Bracey, Meyers, Grauer, and Smith A 50-something-year-old female with a history of an unknown personality disorder and alcohol use disorder arrived via EMS following cardiac arrest with return of spontaneous circulation. Circulation. The described rhythm was an irregular, wide complex rhythm. JAMA Intern Med. 2017.3191.

Tachycardia 131

Tachycardia Cardiac Arrest ICU Blog 131

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142203-A4142203, November 12, 2024. Background:Donation after Circulatory Death (DCD) donor hearts are rarely utilized for transplantation following more than 30 minutes of ischemia. Hearts were procured and mitochondria isolated. Immunoblotting was used to measure CPN1/2 activation.

Ischemia 40

Ischemia Transplant Cardiac Function Circulation 40

Stroke Journal

FEBRUARY 1, 2024

The primary outcome measure was successful recanalization defined as modified Thrombolysis in Cerebral Ischemia (mTICI) score of 2b or higher. Data from 29 stroke centers for 10,229 AIS patients treated with MT for LVO between January 2010 and December 2022 was investigated.

Circulation 40

Circulation Stroke Strokes Thrombolysis 40

Dr. Smith's ECG Blog

JULY 21, 2024

There is no definite evidence of acute ischemia. (ie, Simply stated — t he patient was having recurrent PMVT without Q Tc prolongation, and without evidence of ongoing transmural ischemia. ( Some residual ischemia in the infarct border might still be present. Both episodes are initiated by an "R-on-T" phenomenon.

Arrhythmia 131

Arrhythmia Cardiogenic Shock Bradycardia Defibrillator 131

Stroke Journal

FEBRUARY 1, 2024

The bootstrap resampling method was considered internal validation of the model.Results:Age (< 70 years), premorbid status (mRS 0), National Institutes of Health Stroke Scale (NIHSS) (< 20), and recanalization status after the MT (modified Thrombolysis in Cerebral Ischemia [mTICU] ≥2b) were related to 90-day mRS 0-3.

Circulation 40

Circulation Stroke Strokes Outcomes 40

Dr. Smith's ECG Blog

DECEMBER 7, 2023

Circulation: Cardiovascular Interventions , 7(5), 645–655. This proves effective treatment of the recurrent ischemia. The patient had no further symptoms of ischemia. EKG 3 is diagnostic for developing re-occlusion, and EKG 4 proves that the nitrates relieved the ischemia. = Buller, C. Starovoytov, A., Robinson, S.,

SCAD 124

SCAD Ischemia Coronary Artery Disease Cardiomyopathy 124

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4141224-A4141224, November 12, 2024. Similarly, when GA was considered as a categorical variable, in the fully adjusted model, GA was associated with MACCEs, ischemia-driven revascularization, and all-cause mortality, with P values all less than 0.05. years, and men accounted for 61.8%.

Risk Factors 40

Risk Factors Ischemia Myocardial Infarction Outcomes 40

Dr. Smith's ECG Blog

JANUARY 1, 2013

Precordial ST depression may be subendocardial ischemia or posterior STEMI. I have warned in the past that one must think of other etiologies of ischemia when there is tachycardia. Whether it is subendocardial ischemia or posterior STEMI, if you cannot get it to resolve, you must activate the cath lab. There is no ST elevation.

STEMI 52

STEMI Ischemia Chest Pain Myocardial Infarction 52