JAMA Cardiology

JANUARY 2, 2024

This genetic association study investigates if mendelian randomization can identify associations between circulating cardiovascular disease–related proteins and hypertensive disorders of pregnancy.

Circulation 40

Circulation Hypertension Cardiovascular Disease 40

Medical Xpress - Cardiology

JULY 2, 2024

For example, blood pressure changes during exercise (EBP) can reveal a latent tendency toward future development of hypertension. At present, there is no reliable circulating biomarker—a protein or other molecule present in the blood stream—indicative of hypertension risk.

Hypertension 52

Hypertension Blood Pressure Exercise Physiology 52

Hypertension Journal

FEBRUARY 21, 2024

Hypertension, Ahead of Print. BACKGROUND:The mesenteric venous reservoir plays a vital role in mediating blood volume and pressure changes and is richly innervated by sympathetic nerves; however, the precise nature of venous sympathetic regulation and its role during hypertension remains unclear. mL/min) but efflux in SH rats (−1.0±1.0

Hypertension 45

Hypertension Circulation 45

Frontiers in Cardiovascular Medicine

JANUARY 2, 2024

If pulmonary hypertension is additionally involved with vasoplegic syndrome, circulation management becomes much more complicated. The aim of this study is to investigate whether pituitrin is beneficial for the postoperative outcomes in patients with pulmonary hypertension undergoing cardiac surgery.

Pulmonary 59

Pulmonary Hypertension Outcomes Circulation 59

Hypertension Journal

DECEMBER 3, 2024

Hypertension, Ahead of Print. Colocalization analyses were then used to investigate whether the circulating proteins and blood pressure traits shared causal genetic variants.

Blood Pressure 40

Blood Pressure Circulation Hypertension Physiology 40

HCPLive

JUNE 25, 2024

Jesudian, MD, discusses strategies to prevent the progression of cirrhosis, which include targeting microbiome abnormalities to improve the gut-liver axis, enhancing circulatory function, treating the inflammatory state, and addressing portal hypertension.

Circulation 52

Circulation Hypertension 52

Frontiers in Cardiovascular Medicine

MAY 26, 2024

BackgroundAlthough Hypertension (HTN) is considered to be a cardiovascular disease caused by multiple factors, the cause of it is still unknown.

Hypertension 59

Hypertension Cardiovascular Disease Circulation 59

Frontiers in Cardiovascular Medicine

MAY 8, 2024

Patients with pulmonary hypertension associated with a left-right shunt include a wide spectrum of pathophysiological substrates, ranging from those characterized by pulmonary over-circulation to those with advanced pulmonary vascular disease.

Congenital Heart Disease 52

Congenital Heart Disease Pulmonary Hypertension Congenital 52

Hypertension Journal

JANUARY 14, 2025

Hypertension, Volume 82, Issue 2 , Page e4-e4, February 1, 2025.

Circulation 45

Circulation Hypertension 45

Journal of the American Heart Association

DECEMBER 24, 2024

BackgroundChronic arterial hypertension restructures the vascular architecture of the brain, leading to a series of pathological responses that culminate in cerebral smallvessel disease. Journal of the American Heart Association, Ahead of Print. Microvessels were isolated for gene expression profiling and invitro pericyte expansion.

Hypertension 45

Hypertension Biomarkers Circulation 45

Circulation: Heart Failure

NOVEMBER 11, 2024

Circulation: Heart Failure, Ahead of Print. Background:Distinguishing hypertrophic cardiomyopathy (HCM) from other cardiomyopathies with left ventricular hypertrophy (LVH), such as hypertensive LVH, transthyretin amyloid cardiomyopathy (ATTR-CM), and aortic stenosis (AS), is sometimes challenging. and |log2(fold change)| >0.5

Cardiomyopathy 40

Cardiomyopathy Biomarkers Circulation Hypertension 40

Wellnest

DECEMBER 18, 2023

These groundbreaking developments offer a paradigm shift in the management of resistant hypertension, especially when it is extremely difficult to achieve blood pressure control through conventional means, such as lifestyle modifications and various drug therapies. But what is resistant hypertension, and why does it require renal denervation?

Hypertension 52

Hypertension Blood Pressure Ablation Reimbursement 52

Journal of the American Heart Association

MARCH 18, 2024

Changes in BCAA homeostasis have emerged as pivotal contributors in the pathophysiology of several cardiometabolic diseases, including type 2 diabetes, obesity, hypertension, atherosclerotic cardiovascular disease, and heart failure.

Circulation 40

Circulation Obesity Heart Failure Cardiovascular Disease 40

Circulation

MARCH 30, 2025

Circulation, Volume 151, Issue 13 , Page e866-e866, April 1, 2025.

Hypertension 45

Hypertension Circulation 45

Hypertension Journal

FEBRUARY 16, 2024

Hypertension, Ahead of Print. Such stress alters the content and increases the release of syncytiotrophoblast extracellular vesicles (STB-EVs) into the maternal circulation. Such stress alters the content and increases the release of syncytiotrophoblast extracellular vesicles (STB-EVs) into the maternal circulation.

Circulation 45

Circulation Hypertension 45

Circulation

FEBRUARY 25, 2024

Circulation, Volume 149, Issue 9 , Page 707-716, February 27, 2024. This is most evident in hypertension where several small interfering RNA–based drugs have proven to be effective in managing high blood pressure in several clinical trials. RNA therapeutics hold significant promise in the treatment of cardiovascular diseases.

COVID-19 102

COVID-19 Cardiovascular Disease Blood Pressure Technology 102

Hypertension Journal

FEBRUARY 9, 2024

Hypertension, Ahead of Print. BACKGROUND:High circulating DPP3 (dipeptidyl peptidase 3) has been associated with poor prognosis in critically ill patients with circulatory failure. In such situation, DPP3 could play a pathological role, putatively via an excessive angiotensin peptides cleavage.

Circulation 40

Circulation Blood Pressure Hypertension 40

Hypertension Journal

DECEMBER 20, 2023

Hypertension, Ahead of Print. BACKGROUND:The pathogenesis of chronic thromboembolic pulmonary hypertension (CTEPH) is multifactorial and growing evidence has indicated that hematological disorders are involved.

Hypertension 49

Hypertension Pulmonary Cardiovascular Disease Circulation 49

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4145840-A4145840, November 12, 2024. The diagnosis of hypertension is associated with a significant increase in the risk of kidney or cardiovascular events, with no prior history of these events. The AAMR for hypertensive heart and renal disease with heart failure was 0.1

Hypertension 40

Hypertension Heart Failure Certification Kidney Disease 40

Circulation

MARCH 9, 2025

Circulation, Volume 151, Issue 10 , Page 716-732, March 11, 2025. Albuminuriaincreased urine albumin excretionis associated with cardiovascular mortality among patients with diabetes, hypertension, chronic kidney disease, or heart failure, as well as among adults with few cardiovascular risk factors.

Kidney Disease 83

Kidney Disease Biomarkers Heart Failure Risk Factors 83

Circulation

MAY 27, 2024

Circulation, Volume 149, Issue 22 , Page 1770-1774, May 28, 2024.

Pulmonary 45

Pulmonary Hypertension Circulation 45

Circulation

JANUARY 12, 2024

Circulation, Ahead of Print. BACKGROUND:Pulmonary hypertension, characterized by vascular remodeling, currently lacks curative therapeutic options. The dysfunction of pulmonary artery endothelial cells plays a pivotal role in the initiation and progression of pulmonary hypertension (PH).

Pulmonary 45

Pulmonary Hypertension Biomarkers Circulation 45

Circulation

SEPTEMBER 29, 2024

Circulation, Volume 150, Issue 14 , Page 1087-1089, October 1, 2024.

Heart Disease 49

Heart Disease Hypertension Circulation 49

Stroke Journal

FEBRUARY 1, 2024

Objective:Forward head posturing (FHP) has been associated with chronic anatomic vertebral artery disturbances possibly leading to posterior circulation ischemia. The data supporting FHP as a true risk factor of posterior circulation stroke has not been well established. The average C2 tilt of cases was 22.9 degrees compared to 17.7

Risk Factors 40

Risk Factors Circulation Atrial Fibrillation Ischemia 40

DAIC

NOVEMBER 8, 2024

Additional details and the notice can be found here: [link] The Paradise uRDN system is designed to lower blood pressure by denervating the sympathetic nerves surrounding the renal arteries, reducing the overactivity that can lead to hypertension.

CMS 40

CMS Ultrasound Blood Pressure Reimbursement 40

Circulation

FEBRUARY 5, 2025

Circulation, Ahead of Print. BACKGROUND:Although combination antiretroviral therapy has increased life expectancy in people living with HIV, it has led to a marked increase in the prevalence of hypertension, the cause of which is unknown.

Hypertension 45

Hypertension Blood Pressure Transplant Circulation 45

Circulation

JUNE 4, 2024

Circulation, Ahead of Print. We projected through 2050, overall and by age and race and ethnicity, accounting for changes in disease prevalence and demographics.RESULTS:We estimate that among adults, prevalence of hypertension will increase from 51.2% in 2020 to 61.0% Diabetes (16.3% to 26.8%) and obesity (43.1% to 3.8%), stroke (3.9%

Risk Factors 81

Risk Factors Cardiovascular Disease Strokes Stroke 81

Journal of the American Heart Association

FEBRUARY 29, 2024

BackgroundThis study aimed to investigate the causal relationships between branched‐chain amino acids (BCAAs) and the risks of hypertension via meta‐analysis and Mendelian randomization analysis.Methods and ResultsA meta‐analysis of 32 845 subjects was conducted to evaluate the relationships between BCAAs and hypertension.

Hypertension 40

Hypertension Risk Factors Circulation 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4141387-A4141387, November 12, 2024. Additionally, 94 cases of tumor-associated hypertension and 96 cases of primary hypertension were randomly selected for comparison. 13.21) vs. (80.41±10.71) 10.71) mmHg,t=2.332,P=0.021], daytime average diastolic blood pressure [(85.98±13.19)

Blood Pressure 40

Blood Pressure Hypertension BMI Risk Factors 40

CardiacWire

SEPTEMBER 11, 2024

That increase was greatest among younger patients, males, minorities, and patients with hypertension and diabetes. That’s far higher than previous estimates, including a pair of JAMA and Circulation studies that estimated nationwide AFib rates of 2.26M and 5.1M When these results are applied across the U.S., adult population.

AFIB 105

AFIB Atrial Fibrillation Arrhythmia Research 105

Circulation

MARCH 7, 2024

Circulation, Ahead of Print. Balloon pulmonary angioplasty continues to gain traction as a treatment option for patients with chronic thromboembolic pulmonary disease with and without pulmonary hypertension.

Angioplasty 45

Angioplasty Pulmonary Hypertension Document 45

Circulation: Cardiovascular Quality & Outcomes

MARCH 12, 2025

Circulation: Cardiovascular Quality and Outcomes, Ahead of Print.

Hypertension 40

Hypertension Circulation Outcomes 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4146960-A4146960, November 12, 2024. The chi-squared test compared sociodemographic characteristics between HTN stages I and II.Results:Data from 1580 hypertensive participants with blood pressure readings over 130/80 mmHg with or without anti-hypertensive treatment was analyzed.

Hypertension 40

Hypertension Blood Pressure BMI Risk Factors 40

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4147331-A4147331, November 12, 2024. Hypertension can often be seen in settings of obesity, leptin resistance, and insulin resistance, though the exact mechanistic interaction of these conditions has yet to be elucidated. Single cell sequencing was performed on circulating immune cells.

Hypertension 40

Hypertension Blood Pressure Laboratory Obesity 40

Circulation

DECEMBER 22, 2023

Circulation, Ahead of Print. BACKGROUND:Hypertension is a key risk factor for major adverse cardiovascular events but remains difficult to treat in many individuals. Dietary interventions are an effective approach to lower blood pressure (BP) but are not equally effective across all individuals. Intervention studies are warranted.

Hypertension 45

Hypertension Blood Pressure Biomarkers Risk Factors 45

Journal of the American Heart Association

MARCH 7, 2025

BackgroundLifethreatening pulmonary arterial hypertension (PAH) still lacks a direct therapeutic approach targeted to the molecular defects associated with the disease. Journal of the American Heart Association, Ahead of Print. No effect of rimeporide was detected in control rats.

Pulmonary 45

Pulmonary Hypertension Circulation 45

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4143390-A4143390, November 12, 2024. Introduction:Obesity is rising in prevalence worldwide and co-exists in patients with group 1 pulmonary hypertension (PH). Clinical and hemodynamic implications of having obesity in group 1 PH remain unknown.Hypothesis. vs 1.38 ± 0.84 mL/mm of Hg, p=.0002)

Obesity 40

Obesity Pulmonary Hypertension Diabetes 40