Circulation, Hemorrhage and Ischemia

Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study

Stroke Journal

JANUARY 4, 2024

These studies mainly concerned anterior circulation occlusions. All patients with a posterior circulation occlusion were included. Although symptomatic intracranial hemorrhages occurred more often in the IVT group (4.8% Our results are in line with the literature on the anterior circulation.

Thrombolysis

Thrombolysis Circulation Hemorrhage Ischemia

Arterial-Lymphatic-Like Endothelial Cells Appear in Hereditary Hemorrhagic Telangiectasia 2 and Contribute to Vascular Leakage and Arteriovenous Malformations

Circulation

OCTOBER 21, 2024

Circulation, Ahead of Print. BACKGROUND:Arteriovenous malformations (AVMs) are characteristic of hereditary hemorrhagic telangiectasia. Loss-of-function mutations in the activin receptorlike kinase 1 (Alk1) are linked to hemorrhagic telangiectasia type 2.METHODS:Endothelial-specific

Hemorrhage

Hemorrhage Transplant Ischemia Pulmonary

Abstract 225: Rescue Stenting for Posterior Circulation Strokes

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

IntroductionIntracranial atherosclerotic disease (ICAD) is associated with up to 32% of posterior circulation strokes.1 5 However, most of the existing literature focuses on anterior circulation. Stroke: Vascular and Interventional Neurology, Volume 3, Issue S2 , November 1, 2023.

Stents

Stents Stent Circulation Stroke

Webinars

Bridging Innovation & Patient Care: The Growing Role of AI

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Abstract WP192: Impact of Second Line Thrombectomy Technique Following Failed First Pass Thrombectomy for Anterior Circulation Stroke: To Switch or Not to Switch?

Stroke Journal

FEBRUARY 1, 2024

The primary outcome measure was successful recanalization defined as modified Thrombolysis in Cerebral Ischemia (mTICI) score of 2b or higher. 90-day modified Rankin score (mRS) 0-2, mortality and symptomatic hemorrhage were used as secondary outcomes.

Circulation

Circulation Stroke Strokes Thrombolysis

Does this T wave pattern mean anything?

Dr. Smith's ECG Blog

OCTOBER 23, 2023

Edited by Bracey, Meyers, Grauer, and Smith A 50-something-year-old female with a history of an unknown personality disorder and alcohol use disorder arrived via EMS following cardiac arrest with return of spontaneous circulation. Circulation. The described rhythm was an irregular, wide complex rhythm. JAMA Intern Med. 2017.3191.

Tachycardia

Tachycardia Cardiac Arrest ICU Blog

MARVEL: A Randomized Double?Blind, Placebo?Controlled Trial in Patients Undergoing Endovascular Therapy: Study Rationale and Design

Stroke: Vascular and Interventional Neurology

JANUARY 26, 2024

BACKGROUNDSteroids have pleiotropic neuroprotective actions including the regulation of inflammation and apoptosis which may influence the effects of ischemia on neurons, glial cells, and blood vessels. Stroke: Vascular and Interventional Neurology, Ahead of Print.

Ischemia

Ischemia Stroke Strokes Circulation

Important Complications of Eisenmenger Syndrome

All About Cardiovascular System and Disorders

MARCH 26, 2024

This highlights one of the most important complications of Eisenmenger syndrome, that is airway hemorrhage. Airway hemorrhage can occur in those who ascend to high altitude and during air travel. But if you go by the statistics, majority of the hemorrhages occur at sea level or ordinary level of height.

VSD

VSD Pulmonary Hemorrhage Hypertension

Abstract 4142098: Clinical Link of Neutrophilia to Neovascularization and Fibrinolysis

Circulation

NOVEMBER 11, 2024

Circulation, Volume 150, Issue Suppl_1 , Page A4142098-A4142098, November 12, 2024. The anti-angiogenic impact of neutrophil elastase clouded the understanding of the role of neutrophils in promoting neovascularization (NV) and fibrinolysis in patients with chronic limb-threatening ischemia (CLTI). J Tissue Eng Regen Med.

Document

Document Circulation Ischemia Hemorrhage

Abstract TP188: Diving MCA and First-Pass Reperfusion: A Subgroup Analysis of the Arise II Study

Stroke Journal

FEBRUARY 1, 2024

Here, we investigate the association of middle cerebral artery(MCA) tortuosity on radiographic and functional outcome.Methods:The Analysis of Revascularization in Ischemic Stroke with EmboTrap II was utilized to identify patients with anterior circulation stroke. Likewise, the rate of mTICI≥2c was higher in group A (54.5%) vs 36.4%

Atrial Fibrillation

Atrial Fibrillation Thrombolysis Ischemia Hemorrhage

A teenager involved in a motor vehicle collision with abnormal ECG

Dr. Smith's ECG Blog

FEBRUARY 6, 2024

The ECG shows sinus tachycardia with RBBB and LAFB, without clear additional superimposed signs of ischemia. Massive Transfusion for Motorcycle Collision with Hemorrhage, Troponin Elevated. Circulation: Cardiovascular Imaging. Chest trauma was suspected on initial exam. Here is his initial ECG around 1330: What do you think?

Tachycardia

Tachycardia Dysrhythmia Atrial Fibrillation Bradycardia

Middle Aged Woman with Asystolic Cardiac Arrest, Resuscitated: Cath Lab?

Dr. Smith's ECG Blog

OCTOBER 20, 2013

This ECG is diagnostic of diffuse subendocardial ischemia. Because the patient had asystole, was resuscitated without difficulty, and had no neurologic function, suspected a cerebral hemorrhage was suspected as the etiology of the arrest, specifically subarachnoid hemorrhage. Circulation 122:Abstract 101.

Cardiac Arrest

Cardiac Arrest STEMI Hemorrhage Hospital

46 year old with chest pain develops a wide complex rhythm -- see many examples

Dr. Smith's ECG Blog

AUGUST 9, 2024

below) Other examples of AIVR: Young man with Gunshot wound to right chest with hemorrhagic shock, but bullet path not near heart. Possible mechanisms of ventricular arrhythmias elicited by ischemia followed by reperfusion. Circulation Research , 56 (2), 184–194. Circulation , 63 (2), 333–340. Leave it alone. Moffat, M.

Chest Pain

Chest Pain Arrhythmia Myocardial Infarction STEMI

How does Acute Total Left Main Coronary occlusion present on the ECG?

Dr. Smith's ECG Blog

AUGUST 9, 2019

Post by Smith and Meyers Sam Ghali ( [link] ) just asked me (Smith): "Steve, do left main coronary artery *occlusions* (actual ones with transmural ischemia) have ST Depression or ST Elevation in aVR?" That said, complete LM occlusion would be expected to have subepicardial ischemia (STE) in these myocardial territories: STE vector 1.

Myocardial Infarction

Myocardial Infarction Ischemia STEMI Cardiogenic Shock

Abstract 221: EARLY EXPERIENCE OF EMBOGUARD BALLOON GUIDE CATHETER IN LARGE VESSEL OCCLUSION THROMBECTOMY

Stroke: Vascular and Interventional Neurology

NOVEMBER 9, 2023

Outcomes included complications, NIHSS at discharge, final modified TICI (thrombolysis in cerebral ischemia) scores including the first‐pass effect (FPE, defined as mTICI 2c/3 after first pass), modified‐FPE (defined as, mTICI 2b‐3 after first pass), symptomatic intracranial hemorrhage (SITS‐MOST definition), and death at discharge.

Thrombolysis

Thrombolysis Ischemia Hemorrhage Stroke

Emergency Department Syncope Workup: After H and P, ECG is the Only Test Required for Every Patient.

Dr. Smith's ECG Blog

APRIL 8, 2015

Also consider non-hemorrhagic volume depletion, dehydration : orthostatic vitals may uncover this [see Mendu et al. (3)]. Evidence of acute ischemia (may be subtle) vii. ST segment and T wave abnormalities consistent with or possibly related to myocardial ischemia. Circulation. Left BBB vi. Pathologic Q-waves viii.

Arrhythmia

Arrhythmia Outcomes Risk Factors Chest Pain

Cardiovascular Update

Intravenous Thrombolysis Before Endovascular Treatment in Posterior Circulation Occlusions: A MR CLEAN Registry Study

Arterial-Lymphatic-Like Endothelial Cells Appear in Hereditary Hemorrhagic Telangiectasia 2 and Contribute to Vascular Leakage and Arteriovenous Malformations

Abstract 225: Rescue Stenting for Posterior Circulation Strokes

Webinars

Abstract WP192: Impact of Second Line Thrombectomy Technique Following Failed First Pass Thrombectomy for Anterior Circulation Stroke: To Switch or Not to Switch?

Does this T wave pattern mean anything?

MARVEL: A Randomized Double?Blind, Placebo?Controlled Trial in Patients Undergoing Endovascular Therapy: Study Rationale and Design

Important Complications of Eisenmenger Syndrome

Abstract 4142098: Clinical Link of Neutrophilia to Neovascularization and Fibrinolysis

Abstract TP188: Diving MCA and First-Pass Reperfusion: A Subgroup Analysis of the Arise II Study

A teenager involved in a motor vehicle collision with abnormal ECG

Middle Aged Woman with Asystolic Cardiac Arrest, Resuscitated: Cath Lab?

46 year old with chest pain develops a wide complex rhythm -- see many examples

How does Acute Total Left Main Coronary occlusion present on the ECG?

Abstract 221: EARLY EXPERIENCE OF EMBOGUARD BALLOON GUIDE CATHETER IN LARGE VESSEL OCCLUSION THROMBECTOMY

Emergency Department Syncope Workup: After H and P, ECG is the Only Test Required for Every Patient.

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