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Circulation Heart Transplant Transplant 
Frontiers in Cardiovascular Medicine
FEBRUARY 5, 2024
Despite developments in circulating biomarker and imaging technology in the assessment of cardiovascular disease, the surveillance and diagnosis of heart transplant rejection has continued to rely on histopathologic interpretation of the endomyocardial biopsy.
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4144084-A4144084, November 12, 2024. Despite being a heart transplantation candidate, she declined revascularization and sought alternative treatments for angina, dyspnea, and daily activity limitations.
DAIC
FEBRUARY 13, 2024
Pictured Left to Right: Members and students of the McGill Gene Editing Laboratory at The Texas Heart Institute in Houston, Texas: Fansen Meng, PhD, Xiao Li, PhD, James Martin, MD, PhD, Rich Li, PhD (back), Maggie Lim (undergraduate student at Rice University front), Yuka Morikawa, PhD, Ann Bromley.
111 
Circulation
JANUARY 28, 2024
Circulation, Volume 149, Issue 5 , Page 339-341, January 30, 2024.
Circulation: Heart Failure
APRIL 4, 2025
Circulation: Heart Failure, Ahead of Print. Heart failure is a global disease with significant morbidity. Heart transplant (HT) can be a lifesaving therapy for select patients with end-stage heart failure.
Circulation
OCTOBER 20, 2024
Circulation, Volume 150, Issue 17 , Page 1313-1314, October 22, 2024.
Circulation
MAY 19, 2024
Circulation, Volume 149, Issue 21 , Page 1667-1669, May 21, 2024.
Circulation
MARCH 30, 2025
Circulation, Volume 151, Issue 13 , Page 910-912, April 1, 2025.
Circulation: Genomic and Precision Medicine
SEPTEMBER 28, 2023
Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 452-461, October 1, 2023. Background:Many cardiovascular disorders propel the development of advanced heart failure that necessitates cardiac transplantation. of patients with unexplained end-stage cardiomyopathy.
Circulation
SEPTEMBER 10, 2024
Circulation, Ahead of Print. Early identification of kidney dysfunction in patients with advanced heart failure is crucial for timely interventions. Hemodynamic derangements and maladaptive neurohormonal upregulations contribute to fluctuations in kidney indices and electrolytes that may recover with guideline-directed medical therapy.
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4146828-A4146828, November 12, 2024. Heart transplantation remains a vital treatment for end-stage heart failure, yet the scarcity of suitable donor hearts makes the treatment unavailable to many patients in critical need.
40 
Circulation: Heart Failure
AUGUST 1, 2024
Circulation: Heart Failure, Ahead of Print.
Circulation
FEBRUARY 26, 2024
Circulation, Ahead of Print. Individual programs oftentimes develop upper age limits for various interventional strategies for their patients, including heart transplantation and durable left ventricular assist devices.
Circulation: Heart Failure
DECEMBER 11, 2023
Circulation: Heart Failure, Ahead of Print.
Circulation: Heart Failure
DECEMBER 9, 2024
Circulation: Heart Failure, Ahead of Print.
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4146920-A4146920, November 12, 2024. Cox regression results showed that there is an increased risk of mortality in patients who did not receive transfusions before transplant (p<0.0001).Conclusion:While
40 
Circulation: Heart Failure
FEBRUARY 5, 2024
Circulation: Heart Failure, Ahead of Print. BACKGROUND:Cardiac allograft vasculopathy (CAV) is the leading cause of late graft dysfunction in heart transplantation. Only patients in the moderate to high risk cluster developed the International Society for Heart and Lung Transplantation CAV 2-3 at 5 years (P=0.02).
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4113494-A4113494, November 12, 2024. End-stage ischemic heart disease necessitates heart transplantation, and emerging cell therapy presents a promising solution to address donor scarcity.
40 
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4146823-A4146823, November 12, 2024. Heart transplant rates were low but increased slightly in 2020 for patients without CHD, with DV and SV CHD patients showing fluctuating rates peaking in 2018 and 2019, then declining in 2020. Patients without CHD were older (mean age 71.5
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4134590-A4134590, November 12, 2024. The association between a lower rate of MAE and EMB persisted in the multivariate model when those with heart transplant who had EMB were compared to those without heart transplant who did not have EMB p=0.001.
Circulation: Heart Failure
JANUARY 16, 2025
Circulation: Heart Failure, Ahead of Print. BACKGROUND:Right ventricular dysfunction (RVD) is common in patients with heart failure with reduced ejection fraction, and it is associated with poor prognosis.
40 
Circulation: Heart Failure
MARCH 8, 2024
Circulation: Heart Failure, Ahead of Print. Centers performing at least 1 heart transplant or left ventricular assist device were classified as ATCs. Patient characteristics, outcomes, and procedural volume were compared among 3 cohorts: admissions to non-ATCs, admissions to ATCs, and transfers to ATCs.
Circulation
JANUARY 18, 2024
Circulation, Ahead of Print. BACKGROUND:Cardiolipin is a mitochondrial-specific phospholipid that maintains integrity of the electron transport chain (ETC) and plays a central role in myocardial ischemia/reperfusion injury. Tafazzin is an enzyme that is required for cardiolipin maturation.
DAIC
APRIL 30, 2024
Study shows that cardiac spheroids, derived from human induced pluripotent stem cells, can be easily transported and injected into damaged areas of the heart to promote its regeneration and recovery of function. Heart attacks typically kill millions of cardiac muscle cells, leaving the heart in a weakened state.
105 
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4139383-A4139383, November 12, 2024. Background:Immunosuppressive (IS) therapy is currently used as first-line treatment for heart transplant (HTx) rejection. However, they are not without complications, and less toxic therapies are needed. years, males: 58.4%).
Circulation
JANUARY 9, 2025
Circulation, Ahead of Print. BACKGROUND:The United Network of Organ Sharing made changes to the priority for allocation of hearts for transplantation (HT) in 2016 for pediatric patients and 2018 for adult patients.
Circulation: Cardiovascular Imaging
APRIL 2, 2024
Circulation: Cardiovascular Imaging, Ahead of Print. BACKGROUND:In heart transplant recipients, right ventricular (RV) dysfunction may occur for a variety of reasons. Whether RV dysfunction in the stable phase after heart transplantation is associated with long-term adverse outcomes is unknown. 1.17];P=0.046).
MIBHS
OCTOBER 31, 2024
Left Ventricular Assist Device (LVAD) , a mechanical pump that helps the heart pump blood more effectively. Implantable Cardioverter-Defibrillator (ICD) to help manage dangerous heart rhythms. Heart Transplant may be considered in severe cases where other treatments have failed. Avoid smoking and limit alcohol intake.
DAIC
MAY 15, 2024
It can be used while waiting for a heart transplant, to help the heart recover, or as a permanent solution when a transplant isn't an option. HeartMate 3 LVAS takes over the pumping function of the left ventricle, the main pumping chamber of the heart.
105 
DAIC
APRIL 15, 2024
The HeartMate II and 3 are used for both short- and long-term support in adult patients with severe left ventricular heart failure. It can be used while waiting for a heart transplant, to help the heart recover, or as a permanent solution when a transplant isn't an option. Reason for Recall Abbott/Thoratec Corp.
105 Circulation: Heart Failure
NOVEMBER 6, 2023
Circulation: Heart Failure, Ahead of Print.
Circulation: Heart Failure
DECEMBER 10, 2024
Circulation: Heart Failure, Ahead of Print. BACKGROUND:Cardiac allograft vasculopathy (CAV) leads to impaired myocardial blood flow (MBF), increasing the risk of cardiovascular death or retransplant among heart transplantation (HT) recipients.
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4144326-A4144326, November 12, 2024. It has changed the fate of young patients with large tumors who would have otherwise needed heart transplants, offering high suture strength and reducing postoperative complications. During a median follow-up period of 17.4
40 Circulation: Heart Failure
FEBRUARY 1, 2024
Circulation: Heart Failure, Ahead of Print. BACKGROUND:In 2018, an algorithm-based allocation system for heart transplantation (HT) was implemented in France. The cumulative incidence of waitlist mortality estimated with competing risk analysis and incidence of transplantation were compared between diagnosis groups.
Circulation: Cardiovascular Imaging
DECEMBER 18, 2023
Circulation: Cardiovascular Imaging, Volume 16, Issue 12 , Page e015671, December 1, 2023. LV global longitudinal strain did not add diagnostic value but was prognostic for composite end points of death, heart transplantation, or ventricular arrhythmia (log-rankP=0.04).CONCLUSIONS:In
Circulation: Genomic and Precision Medicine
SEPTEMBER 6, 2023
Circulation: Genomic and Precision Medicine, Volume 16, Issue 5 , Page 421-430, October 1, 2023. Background:Variants in theDMDgene, that encodes the cytoskeletal protein, dystrophin, cause a severe form of dilated cardiomyopathy (DCM) associated with high rates of heart failure, heart transplantation, and ventricular arrhythmias.
Circulation: Heart Failure
FEBRUARY 1, 2024
Circulation: Heart Failure, Ahead of Print. BACKGROUND:Clinical evaluation of central venous pressure is difficult, depends on experience, and is often inaccurate in patients with chronic advanced heart failure. 0.84]) and confirmed in the validation cohort (receiver operating characteristic, 0.82 [95% CI, 0.73–0.92]).
Dr. Smith's ECG Blog
JUNE 2, 2023
J Electrocardiol, 42 (2009), pp. e5 Article Download PDF Google Scholar 3 RNW Hauer, MGPJ Cox, JA Groeneweg Impact of new electrocardiographic criteria in arrhythmogenic cardiomyopathy Front Physiol, 3 (2012), p.
96 
Cardiology Update
APRIL 9, 2024
The Impella CP is a catheter-based, axial flow pump that pumps blood directly from the left ventricle into the circulation. The primary endpoint was a composite of all-cause mortality, left ventricular assist device (LVAD)/heart transplantation, HF hospitalizations, worsening HF, and KCCQ score changes.
52 
Society of Thoracic Surgeons - Research
APRIL 20, 2023
Part 1: Concepts, Indicator Variables, and Controversies The Annals of Thoracic Surgery January 2022 Arman Kilic Supplementing Existing Societal Risk Models for Surgical Aortic Valve Replacement With Machine Learning for Improved Prediction Journal of the American Heart Association November 2021 Jared Belle Strategies for Mechanical Right Ventricular (..)
52 
Society of Thoracic Surgeons - Research
APRIL 20, 2023
Institutional Coronary Artery Bypass Case Volumes and Outcomes European Journal of Heart Failure October 2023 Makoto Mori 1 Robotic Mitral Valve Repair for Degenerative Mitral Regurgitation The Annals of Thoracic Surgery August 2023 Carlos Diaz-Castrillion 2 Volume-Failure to Rescue Relationship in Acute Type A Aortic Dissections: An Analysis of The (..)
52 Circulation: Heart Failure
FEBRUARY 20, 2024
Circulation: Heart Failure, Ahead of Print. Background:Black heart transplant patients are at higher risk of acute rejection (AR) and death than White patients. The incidence of AR was higher in Black patients compared with White patients (43% versus 19%;P=0.002).
Dr. Paddy Barrett
MAY 31, 2024
The prevalence of smoking back in the 1950s would have been much higher, but even recent studies on ‘healthy’ heart transplant donors who died from events such as road traffic accidents still show high rates of very early-stage plaque buildup 4. Circulation. Circulation. Am J Cardiol. 2006 Jan 3;113(1):30-7.
Circulation
NOVEMBER 11, 2024
Circulation, Volume 150, Issue Suppl_1 , Page A4138589-A4138589, November 12, 2024. All patients were prospectively followed for development of new outcome/cardiac events which included hospitalization for acute HF, CVS-related death, heart transplantation, and also diabetic complications.
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