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Physiology Friday #253: Low-carb Matches High-carb for Performance: Is it Time to Question the Obligatory Role of Glycogen for Endurance Exercise?

Physiologically Speaking

Adding to this controversy are questions about carbohydrate supplementation during exercise, particularly whether minimal carbohydrate intake can deliver performance benefits or if higher intakes are necessary to sustain energy levels and delay fatigue. And how effective is minimal carbohydrate supplementation during prolonged exercise?

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Skeletal Muscle Pathology in Pulmonary Arterial Hypertension and Its Contribution to Exercise Intolerance

Journal of the American Heart Association

Pulmonary arterial hypertension is a disease of the pulmonary vasculature, resulting in elevated pressure in the pulmonary arteries and disrupting the physiological coordination between the right heart and the pulmonary circulation.

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Physiology Friday #222: High-intensity Exercise Reduces Senescent “Pro-aging” Cells

Physiologically Speaking

Inflammation is also intricately tied to exercise. During exercise, our body mounts an acute inflammatory response, releasing all sorts of cytokines, macrophages, and other molecules throughout the circulation. The thing with exercise is that it also exerts an anti-inflammatory effect in the proceeding hours to days.

Exercise 104
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Physiology Friday #194: Exercise "Prehab" Prevents Muscle Loss during Inactivity

Physiologically Speaking

Even for individuals who exercise a lot, the evidence would seem to indicate that moving throughout the day is important to maximize training adaptations. This also seems to apply to exercise — older adults need to more of an exercise stimulus to build or maintain muscle.

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New PAD Guidelines; AHA on Postpartum Care; Exercise Didn't Stop CAC Progression

Med Page Today

Circulation) Recommendations for postpartum care were. (MedPage Today) -- Low-dose rivaroxaban (Xarelto), SGLT2 inhibitors, and GLP-1 receptor agonists have entered multisocietal guidelines on peripheral artery disease (PAD) for the first time.

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O2 pulse slope correlates with stroke volume during exercise in patients with a Fontan circulation

Open Heart

It has been shown to be reduced in patients with a Fontan circulation. We propose that the slope of the O 2 pulse curve may be more reflective of SV during exercise. Conclusion The slope of the O 2 pulse curve to peak exercise may be more reflective of peak SV in the Fontan population than a single peak O 2 pulse value.

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Pulmonary vasodilators and exercise in Fontan circulation: a systematic review and meta-analysis

Heart BMJ

Objective In Fontan circulation, pulmonary arterial hypertension (PAH)-targeted therapies could improve the patients’ exercise capacity. This study aimed to investigate the effects of PAH agents on different exercise parameters in stable Fontan patients by synthesising evidence of randomised controlled trials (RCTs).