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Electronic sock detects unhealthy walking style linked to cardiovascular and diabetic complications

Medical Xpress - ECG

An electronic sock that detects an unhealthy walking style linked with diabetes and poor circulation shows promise for preventing foot ulcers and amputation. The novel research is set to benefit the many patients with diabetes who have clogged arteries in the legs and is presented for the first time at EHRA 2024.

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Ago2 Protects Against Diabetic Cardiomyopathy by Activating Mitochondrial Gene Translation

Circulation

Circulation, Ahead of Print. microRNAs translocate into subcellular organelles to modify genes involved in diabetic cardiomyopathy. Cardiac structure and functions were assessed by echocardiography and catheter manometer system.RESULTS:Ago2 was decreased in mitochondria of diabetic cardiomyocytes.

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Multiplexed MRM-based proteomics for identification of circulating proteins as biomarkers of cardiovascular damage progression associated with diabetes mellitus

Cardiovascular Diabetology

Type 2 diabetes mellitus (T2DM) increases the risk of coronary heart disease (CHD) by 2–4 fold, and is associated with endothelial dysfunction, dyslipidaemia, insulin resistance, and chronic hyperglycaemia.

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The effect of empagliflozin on circulating endothelial progenitor cells in patients with diabetes and stable coronary artery disease

Cardiovascular Diabetology

Diabetes mellitus (DM) is associated with premature atherosclerotic disease, coronary artery disease (CAD) and chronic heart failure (HF), leading to increased morbidity and mortality. Sodium-Glucose Co-transp.

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Circulating exosomal mir-16-2-3p is associated with coronary microvascular dysfunction in diabetes through regulating the fatty acid degradation of endothelial cells

Cardiovascular Diabetology

Coronary microvascular dysfunction (CMD) is a frequent complication of diabetes mellitus (DM) characterized by challenges in both diagnosis and intervention. Circulating levels of microRNAs are increasingly re.

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Inverse relationship between circulating sphingosine-1-phosphate and precursor species and coronary artery calcification score in type 2 diabetes

Cardiovascular Diabetology

Circulating S1P levels including S1P in high-density lip. Sphingosine 1-phosphate (S1P) is a key mediator of lipid signaling with strong immunomodulatory and anti-inflammatory effects.

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Current Status and Principles for the Treatment and Prevention of Diabetic Foot Ulcers in the Cardiovascular Patient Population: A Scientific Statement From the American Heart Association

Circulation

Circulation, Ahead of Print. Despite the known higher risk of cardiovascular disease in individuals with type 2 diabetes, the pathophysiology and optimal management of diabetic foot ulcers (DFUs), a leading complication associated with diabetes, is complex and continues to evolve.