The New England Journal of Medicine

APRIL 2, 2025

In patients with posterior circulation stroke for whom thrombectomy was not planned, alteplase administered 4.5 to 24 hours after stroke onset resulted in less disability at 90 days than standard treatment.

Circulation 70

Circulation Stroke Strokes 70

Medical Xpress - Cardiology

JANUARY 3, 2024

Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

Hypertension 132

Hypertension Circulation Blood Pressure Research 132

American College of Cardiology

APRIL 14, 2025

highlight the increasing prevalence of pregnancies among patients with Fontan circulation, a population characterized by significant obstetric risk. The findings of a 2023 analysis by Sobhani et al. The physiological demands of pregnancy exacerbate the unique hemodynamic challenges inherent to Fontan physiology.

Circulation 64

Circulation Physiology Outcomes Article 64

HCPLive

JUNE 7, 2024

These data indicate the benefits of implementing individual protective measures in winter by patients with COPD.

Circulation 101

Circulation 101

American College of Cardiology

APRIL 23, 2025

With improved survival of patients with single-ventricle (SV) congenital heart disease (CHD), there is a growing population of patients with Fontan circulation.

Circulation 58

Circulation Congenital Heart Disease Congenital Heart Disease 58

Medical Xpress - Cardiology

APRIL 15, 2024

An analysis of the biomolecule substudy of the EAST–AFNET 4 trial has revealed that biomolecule concentrations in the blood of patients with atrial fibrillation can be used to identify patients at high and low cardiovascular risk. The findings were published in Cardiovascular Research.

Atrial Fibrillation 111

Atrial Fibrillation Circulation Research 111

Circulation

APRIL 6, 2025

Circulation, Volume 151, Issue 14 , Page 973-975, April 8, 2025.

Circulation 45

Circulation 45

European Journal of Heart Failure

JANUARY 21, 2025

Our study aimed to evaluate whether circulating levels of growth differentiation factor-15 (GDF-15) could predict adverse changes in echocardiographic indexes of cardiac structure and function in an initially healthy populational familial cohort with a long follow-up (STANISLAS cohort).

Circulation 40

Circulation Blood Pressure Cholesterol Research 40

Circulation

FEBRUARY 20, 2025

Circulation, Ahead of Print.

Cardiac Arrest 81

Cardiac Arrest Circulation 81

Medical Xpress - Cardiology

APRIL 4, 2025

For patients with mainly mild posterior circulation ischemic stroke who do not receive thrombectomy, alteplase administered at 4.5

Circulation 52

Circulation Stroke Strokes 52

Journal of the American Heart Association

MARCH 21, 2025

BackgroundFontan circulation (FC) in complex congenital heart disease is characterized by altered hemodynamics and associated with Fontanassociated liver disease. Journal of the American Heart Association, Ahead of Print. Patients with FC may exhibit abnormalities in cholate clearance due to abnormal perfusion.

Circulation 75

Circulation Congenital Heart Disease Congenital Physiology 75

Cardiovascular Diabetology

MARCH 4, 2025

Circulating mitochondrial DNA (mtDNA) profiles could refine risk stratification, but current methods do not account for different fractions. Mitochondrial dysfunction is a hallmark of cardiometabolic diseases.

Circulation 52

Circulation Research 52

Circulation

APRIL 17, 2025

Circulation, Ahead of Print. Cardiovascular disease remains a leading cause of morbidity and mortality in adults despite recent scientific advancements. Although people are living longer lives, there may be an adverse impact on quality of life, necessitating a greater need for palliative care services and support.

Cardiovascular Disease 81

Cardiovascular Disease Quality of Life Circulation Research 81

Circulation

APRIL 7, 2025

Circulation, Ahead of Print. Populations most affected by cardiovascular health disparities, including underrepresented populations with lower socioeconomic status, people with disabilities, and those living in underserved rural communities, are disproportionately exposed to adverse social determinants of health.

Technology 79

Technology Health Disparities Cardiovascular Disease Circulation 79

Circulation

APRIL 10, 2025

Circulation, Ahead of Print. The Physical Activity Guidelines for Americans supports sitting less and moving more. Growing evidence suggests that a waking behavior profile with less sedentary behavior and more light-intensity physical activity is associated with more favorable cardiovascular health.

Blood Pressure 83

Blood Pressure Cardiovascular Disease Outcomes Hypertension 83

Frontiers in Cardiovascular Medicine

APRIL 2, 2025

BackgroundIn-hospital cardiac arrest (IHCA) refers to the occurrence of cardiac arrest in hospitalized patients requiring chest compressions and/or defibrillation, with only about one-third of patients achieving return of spontaneous circulation (ROSC) after cardiopulmonary resuscitation.

Cardiac Arrest 52

Cardiac Arrest Circulation Hospital Defibrillator 52

Circulation

FEBRUARY 13, 2025

Circulation, Ahead of Print. Critical care cardiology refers to the practice focus of and subspecialty training for the comprehensive management of life-threatening cardiovascular diseases and comorbid conditions that require advanced critical care in an intensive care unit.

Critical Care 72

Critical Care Myocardial Infarction Research Cardiovascular Disease 72

Cardiovascular Diabetology

FEBRUARY 20, 2025

Circulating S1P levels including S1P in high-density lip. Sphingosine 1-phosphate (S1P) is a key mediator of lipid signaling with strong immunomodulatory and anti-inflammatory effects.

Circulation 52

Circulation Diabetes Research 52

Journal of the American Heart Association

APRIL 10, 2025

BackgroundIntracranial anterior circulation large artery occlusion (ACLAO) is a predominant cause of ischemic stroke. Although collateral circulation plays a critical role in stroke outcomes, the genetic and environmental factors affecting collateral development are not fully understood.

Circulation 40

Circulation Diabetes Outcomes Stroke 40

American College of Cardiology

MARCH 31, 2025

25 in Chicago and simultaneously published in Circulation: Cardiovascular Imaging.

Plaque 62

Plaque Cardiovascular Imaging Circulation Article 62

Open Heart

MARCH 22, 2025

Background Mechanical stress on the heart is commonly considered the sole stimulus explaining the synthesis and release of circulating natriuretic peptides and their derivatives. Conclusion Myocardial oxygen metabolism directly regulates the plasma levels of natriuretic peptides in heart diseases.

Myocardial Infarction 52

Myocardial Infarction Circulation Heart Disease 52

Circulation

JANUARY 27, 2025

Circulation, Ahead of Print.

Heart Disease 81

Heart Disease Peripheral Arterial Disease Stroke Strokes 81

Circulation: Cardiovascular Interventions

MARCH 9, 2025

Circulation: Cardiovascular Interventions, Ahead of Print. Background:Nickel-containing devices, such as the Amplatzer PFO Occluder and Gore Cardioform Septal Occluder (GSO), are used for transcatheter patent foramen ovale (PFO) closure. However, the impact of nickel hypersensitivity on post-procedural outcomes remains poorly understood.

Chest Pain 70

Chest Pain Cardiovascular Interventions Document Arrhythmia 70

Circulation

DECEMBER 3, 2024

Circulation, Ahead of Print. Smokeless oral nicotine products are addictive, and their use has potential adverse effects on some but not all biomarkers of cardiovascular risk. The use of some types of these products, for instance, is associated with an increased mortality risk in those with ischemic heart or cerebrovascular disease.

Cardiovascular Disease 73

Cardiovascular Disease Cerebrovascular Disease Pharmacology Biomarkers 73

Circulation: Heart Failure

MARCH 14, 2025

Circulation: Heart Failure, Ahead of Print. The most common form of hereditary transthyretin cardiac amyloidosis (hATTR-CA) in the United States and the United Kingdom is the p.V142I variant. About 3% to 4% of patients with African ancestry carry this genetic predisposition to develop signs and symptoms of hATTR-CA.

Genetic predisposition 71

Genetic predisposition Heart Failure Biomarkers Circulation 71

Journal of the American Heart Association

APRIL 10, 2025

BackgroundWe aimed to develop and validate a prognostic score to predict outcomes after endovascular treatment in acute ischemic stroke.MethodsThe prognostic score was developed based on the ACTUAL (Endovascular Treatment for Acute Anterior Circulation Ischemic Stroke) registry. The validation cohort was derived from the Captor trial.

Circulation 40

Circulation Stroke Strokes Outcomes 40

Medical Xpress - Cardiology

AUGUST 20, 2024

The study published in Nature Communications found that phenylacetylglutamine (PAG), produced by gut bacteria as a waste product, then absorbed and formed in the liver, interacts with previously undiscovered locations on beta-2 adrenergic receptors on heart cells once it enters the circulation.

Heart Disease 132

Heart Disease Cardiovascular Disease Circulation Research 132

Science Daily - Heart Disease

SEPTEMBER 23, 2024

A new observational study suggests the position in which responders initially place the two defibrillator pads on the body may make a significant difference in returning spontaneous blood circulation after shock from a defibrillator.

Defibrillator 121

Defibrillator Cardiac Arrest Outcomes Circulation 121

HCPLive

AUGUST 24, 2024

A new study suggests circulating uric acid may be a pro-aging factor in older adults, potentially causing more harm than benefits.

Circulation 116

Circulation 116

European Journal of Heart Failure

JANUARY 17, 2025

Several novel biomarkers enhance the prediction of mortality in CS, compared to conventional parameters such as lactate, with some, such as adrenomedullin and circulating dipeptidyl peptidase 3, also able to predict the development of CS. Some biomarkers reflect systemic inflammation (e.g.

Cardiogenic Shock 75

Cardiogenic Shock Biomarkers Pharmacology Circulation 75

Med Page Today

NOVEMBER 11, 2024

(MedPage Today) -- A small panel of circulating biomarkers may reliably distinguish hypertrophic cardiomyopathy (HCM) from similar conditions that cause left ventricular hypertrophy (LVH), researchers found. From proteomic profiling of nearly.

Cardiomyopathy 116

Cardiomyopathy Biomarkers Circulation Research 116

CardiacWire

OCTOBER 30, 2024

Dr Paddy Barrett – A growing voice in cardiology, with a longevity twist Sensible Medicine – A much needed critical voice in cardiology The Skeptical Cardiologist – Skeptical takes on the latest cardiology topics Circulation on the Run – We appreciate recaps “for busy clinicians on the run” Gregory Katz’s Substack (..)

Interventional Cardiology 105

Interventional Cardiology Cardiovascular Imaging Research Obesity 105

Circulation

JANUARY 12, 2025

Circulation, Volume 151, Issue 2 , Page 196-198, January 14, 2025.

Circulation 97

Circulation 97

Frontiers in Cardiovascular Medicine

APRIL 1, 2025

Ischemic heart disease (IHD), a significant challenge in cardiovascular disease, is characterized by the occlusion of major vessels, obstruction of collateral circulation, and disruption of the capillary networkpathological features closely linked to endothelial cell damage.

Heart Disease 52

Heart Disease Cardiovascular Disease Circulation 52

Frontiers in Cardiovascular Medicine

JANUARY 28, 2025

After treatment, three-months major adverse cardiovascular events (MACE) were assessed as the primary outcome. This therapeutic effect is likely due to the active components of FFDS targeting key proteins: LPL, CD36, FABPpm, L-FABP, LCAT, and CEPT.Clinical Trial Registration[link] identifier (ChiCTR2400080149).

Heart Disease 52

Heart Disease Angina Pharmacology Cholesterol 52

Circulation

MARCH 19, 2025

Circulation, Ahead of Print. The field of cardio-oncology has expanded over the past 2 decades to address the ever-increasing issues related to cardiovascular disease in patients with cancer and survivors.

Cancer 55

Cancer Cardio Oncology Cardiovascular Disease Pediatrics 55

Circulation: Heart Failure

APRIL 21, 2025

Circulation: Heart Failure, Ahead of Print.

Heart Failure 75

Heart Failure Cardiomyopathy Circulation 75