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Circulating bone morphogenetic protein 10 as a novel marker of atrial stress and remodelling in heart failure

Heart BMJ

Background We evaluated the potential of circulating bone morphogenetic protein 10 (BMP10) as a biomarker for atrial stress and remodelling in patients with heart failure (HF), in comparison to N-terminal pro-B-type natriuretic peptide (NT-proBNP). We also assessed the predictive value of BMP10 for adverse clinical outcomes.

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Circulating miRNA-486 as a novel diagnostic biomarker for right ventricular remodeling

Frontiers in Cardiovascular Medicine

ObjectiveClinical practice currently faces a significant shortfall in specific biomarkers needed for diagnosing right ventricular (RV) remodeling in patients with pulmonary hypertension (PH). While small noncoding microRNAs (miRNAs) are crucial regulators of RV remodeling, the biomarker potential of serum miRNAs in this process is little known.

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The human heart may have a hidden ability to repair itself

Medical Xpress - Cardiology

This is according to a new study from Karolinska Institutet published in the journal Circulation. However, after receiving treatment with a supportive heart pump, the capacity of a damaged heart to repair itself with new muscle cells becomes significantly higher, even higher than in a healthy heart.

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Researchers identify circulating proteins linked to preeclampsia and other hypertensive disorders of pregnancy

Medical Xpress - Cardiology

Preeclampsia and other hypertensive disorders of pregnancy—which are characterized by high blood pressure with or without organ dysfunction during the second half of pregnancy—carry considerable short- and long-term risks for both the mother and child. Treatment options (other than expedited delivery) remain limited.

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Study Suggests COPD Preventative Measures Needed During Seasonal Virus Circulations

HCPLive

These data indicate the benefits of implementing individual protective measures in winter by patients with COPD.

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Circulating biomolecules identify patients with atrial fibrillation at high risk of cardiovascular events

Medical Xpress - Cardiology

An analysis of the biomolecule substudy of the EAST–AFNET 4 trial has revealed that biomolecule concentrations in the blood of patients with atrial fibrillation can be used to identify patients at high and low cardiovascular risk. The findings were published in Cardiovascular Research.

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Circulating palmitoyl sphingomyelin levels predict the 10-year increased risk of cardiovascular disease death in Chinese adults: findings from the Da Qing Diabetes Study

Cardiovascular Diabetology

Whether circulating PSM levels. Higher levels of palmitoyl sphingomyelin (PSM, synonymous with sphingomyelin 16:0) are associated with an increased risk of cardiovascular disease (CVD) in people with diabetes.