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The Data For Weight Loss Medications Just Keeps Pouring In.

Dr. Paddy Barrett

For over 50 years, rates of those who are overweight or obese have been rising rapidly. Despite the rise in obesity rates, the growing recognition of it as a global problem and the astronomical sums of money we spend on addressing it, the tide continues to rise. That is until now. Visceral fat levels also fell by close to 50%.

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Physiology Friday #228: Identifying Sleep Patterns that Influence Chronic Disease Risk

Physiologically Speaking

A new study used wearable sleep data to show that several chronic diseases are associated with how we sleep. Results Overall, there were a total of 48 different associations of sleep patterns with chronic disease, all of which were significant even when considering the participants’ habitual physical activity levels.

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Why Walking Might Save Your Life.

Dr. Paddy Barrett

Healthspan A common refrain I hear is, “ I have no interest in living longer if I do not have a good quality of life ” However, one of the single biggest factors impacting your quality of life will be whether or not you have a major chronic disease. More steps are linked to: Less obesity. Am J Hum Biol.

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Are ambulatory blood pressure parameters associated more with central adiposity than with total adiposity? Results of the ELSA-Brasil study

Frontiers in Cardiovascular Medicine

Background Worldwide obesity has a high prevalence, as well as carries a high risk of several chronic diseases, including hypertension. Studies of the association between obesity and ambulatory blood pressure (BP) are scarce and most use only body mass index (BMI) as indicator of adiposity.

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Case Report: Neurological adverse events in subject with myasthenia gravis after PCSK9 inhibitor administration

Frontiers in Cardiovascular Medicine

Case presentation The patient was an obese 72 years old man, past smoker, diagnosed with ischaemic heart disease, type 2 diabetes mellitus and lipid metabolism disorder. Statin treatment was not implemented because of chronic myasthenia gravis and PCSK9i monotherapy [Repatha (evolucamab), 140 mg] was implemented to treat dyslipidaemia.

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3 Powerful Strategies: Combatting Cardiometabolic Risk Factors for Black Americans 

Cardiometabolic Health Congress

Black History Month is a poignant backdrop to the alarming rise in obesity and type 2 diabetes, particularly among those of marginalized populations. This troubling trend has cemented the 100-year reign of cardiovascular diseases (CVD) as the #1 killer in America.

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Physiology Friday #237: An Evolutionary Perspective on Why Exercise Promotes Longevity

Physiologically Speaking

Let’s admit that we face an energy abundance today — in most industrial societies, the problem is caloric surplus and overweight/obesity rather than malnutrition or food scarcity. We are well aware of the risk of overweight and obesity caused by a caloric surplus and a lack of physical activity.

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