American College of Cardiology

MAY 22, 2024

Reduction in low-density lipoprotein cholesterol (LDL-C) levels has consistently demonstrated a reduced risk of atherosclerotic cardiovascular disease (ASCVD). There is extensive evidence from randomized trials that demonstrates the effectiveness of lipid-lowering agents in reducing ASCVD-related events.

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Cholesterol Dementia Hemorrhage Cardiovascular Disease 75

CardiacWire

MARCH 26, 2025

However, not everyone with high cholesterol benefits from statins, leading many drug developers to focus on novel ways to lower LDL-C levels. And fewer strokes (OR: 0.83). Statins are one of the most prescribed drugs in the U.S., with over 25% of all adults 40 and up taking them. Significantly reduced all-cause mortality (OR: 0.81).

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Outcomes Cholesterol Article Research 59

Medical Xpress - Cardiology

JULY 29, 2024

A recently unveiled cardiovascular disease risk calculator that measures a patient's risk for heart attack and stroke is better calibrated and more precise than its previous version, but if current treatment guidelines for cholesterol and blood pressure therapy remain unchanged, the new calculator may have unintended consequences, according to research (..)

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Heart Attack Heart attacks Blood Pressure Stroke 98

Medical Xpress - Cardiology

JANUARY 2, 2025

Regular exercise lowers blood pressure and cholesterol and reduces the chances of having a heart attack or stroke. There's no question that exercise is good for the heart.

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Exercise Blood Pressure Heart Attack Heart attacks 115

DAIC

MAY 7, 2024

A stroke often leads to motor impairment, which is traditionally linked to the extent of damage to the corticospinal tract (CST), a crucial brain pathway for motor control. However, stroke recovery outcomes aren't fully predicted by damage to the CST, suggesting other factors are at play.

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Stroke Strokes Research Public Health 105

Heart 2023 Conference

MAY 9, 2022

Despite this, including them to a person’s food regimen can assist raise “suitable” ldl cholesterol degrees. However, they'll now no longer assist decrease “awful” ldl cholesterol with out extra food regimen changes. Some declare it could additionally decrease low-density lipoprotein (LDL) ldl cholesterol, called awful ldl cholesterol.

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Cholesterol Research Diet Cardiovascular Disease 52

Science Daily - Heart Disease

OCTOBER 23, 2024

In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a new study.

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Blood Pressure Research Dementia Diet 119

Science Daily - Heart Disease

JULY 29, 2024

If current guidelines for cholesterol and high blood pressure treatment remain unchanged, a newly unveiled heart risk calculator would render 16 million people ineligible for preventive therapy.

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Blood Pressure Heart Attack Heart attacks Cholesterol 106

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page AWMP113-AWMP113, February 1, 2025. Introduction:Post-stroke brain stimulation is a promising neurorestorative approach, yet the molecular mechanisms driving recovery remain unclear. Stimulated mice received optogenetic stimulations from post-stroke days (PD) 514.

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Science Daily - Stroke

AUGUST 25, 2023

Middle-aged adults with three or more unhealthy traits including slightly high waist circumference, blood pressure, cholesterol and glucose have heart attacks and strokes two years earlier than their peers, according to new research.

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Heart Attack Heart attacks Blood Pressure Stroke 75

Science Daily - Heart Disease

NOVEMBER 13, 2023

Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives.

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Cardiovascular Disease Cholesterol Diet Stroke 92

Medical Xpress - Cardiology

JANUARY 30, 2025

A study conducted by researchers at the Perelman School of Medicine at the University of Pennsylvania found that by pre-ordering lipid panelsthe tests that can indicate high cholesterol and help predict stroke and heart disease riskclinicians could significantly improve the rate of patients who get the tests done.

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Cholesterol Heart Disease Research Stroke 52

Science Daily - Heart Disease

JUNE 10, 2024

If national guidelines are revised to incorporate a new risk equation, about 40% fewer people could meet criteria for cholesterol-lowering statins to prevent heart disease.

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Heart Disease Heart Attack Heart attacks Cholesterol 108

Science Daily - Heart Disease

FEBRUARY 19, 2024

Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease.

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Heart Disease Heart Attack Heart attacks Atherosclerosis 117

Stroke Journal

FEBRUARY 1, 2024

Stroke, Volume 55, Issue Suppl_1 , Page A47-A47, February 1, 2024. Introduction:Serum remnant lipoprotein particle cholesterol (RLP-C), which includes very-low density lipoproteins (VLDL) and its lipolytic products, contributes to atherosclerotic plaque formation. were women, and 15.7% were Black.

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Medical Xpress - Cardiology

MARCH 18, 2025

All the breakfasts, lunches, dinners, snacks, and desserts show up in your cholesterol, blood pressure, blood sugar, and more. For better or worse, your dietary history is embedded in your body. It's in your bones, gut, heart, blood, and brain.

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Blood Pressure Cholesterol Stroke Strokes 63

DAIC

APRIL 7, 2024

adults—and more than 2 in 5 adults aged 60 years and older—have elevated triglycerides, also known as hypertriglyceridemia , putting them at an increased risk for heart attacks and stroke. It is well known that high levels of low-density lipoprotein (LDL) cholesterol, known as the “bad” cholesterol, heighten cardiovascular risk.

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Cholesterol Heart Attack Heart attacks Myocardial Infarction 116

Circulation

JANUARY 24, 2024

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

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AMS Cardiology

JANUARY 21, 2023

We all want to be heart-healthy and ensuring our cholesterol levels are in the normal range is one of the most critical steps. High cholesterol can increase your risk of severe conditions like heart disease and heart attacks. Continue reading to learn four heart-healthy habits that can improve your cholesterol.

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Cholesterol Diet Blood Pressure Heart Attack 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A12-A12, February 1, 2025.

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Cholesterol Outcomes Stroke Strokes 40

Frontiers in Cardiovascular Medicine

DECEMBER 4, 2024

BackgroundBoth triglyceride-glucose (TyG) index and residual cholesterol (RC) are predictors of stroke; however, to what extent the RC is associated with stroke through TyG index is unclear. The exposure was RC, the mediator was TyG index, and the outcome was stroke which followed up from June, 2011, to June, 2018.

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Cholesterol Stroke Strokes Outcomes 40

Science Daily - Heart Disease

AUGUST 28, 2023

New research details the first oral drug for the treatment of a type of high cholesterol -- called Lp(a) -- that is a potentially more dangerous version of the so called 'bad' cholesterol, LDL, because it is stickier and may be more likely to cause blockages and blood clots in your arteries.

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Open Heart

APRIL 22, 2022

Objectives Elevated low-density lipoprotein cholesterol (LDL-C) increases the risk of recurrent cardiovascular disease (CVD) events. We examined use of lipid-lowering therapy (LLT) following ischaemic stroke, and estimated benefits from guideline-based up-titration of LLT. and women (coefficient –5.1 to –0.9)

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Stroke Strokes Cholesterol Dementia 52

Stroke Journal

FEBRUARY 23, 2025

Stroke, Volume 56, Issue 3 , Page 640-648, March 1, 2025. These divergent trends are at least partially attributable not only to diverging trends in stroke risk factors but may also be due to differences in the impact of stroke risk factors at different ages. Interventions that target these traits may reduce stroke risk.

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Risk Factors Stroke Strokes Blood Pressure 40

Science Daily - Heart Disease

AUGUST 30, 2023

People who have had a stroke called an intracerebral hemorrhage who take cholesterol-lowering drugs called statins may have a lower risk of having another stroke, especially ischemic stroke, compared to people who also had an intracerebral hemorrhage but were not taking statins.

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Stroke Strokes Hemorrhage Cholesterol 40

Journal of the American Heart Association

DECEMBER 19, 2024

BackgroundElevated lowdensity lipoprotein cholesterol is a risk factor for atherosclerotic cardiovascular disease, including acute ischemic stroke (AIS), due to large and smallvessel disease. Cholesterol management guidelines recommend lipidlowering therapy (LLT) to prevent atherosclerotic cardiovascular disease events.

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Stroke Strokes Cholesterol Cardiovascular Disease 40

Medical Xpress - Cardiology

AUGUST 15, 2024

Clogged arteries—which can lead to heart attacks and strokes—can begin to develop in young adulthood. But a new study suggests it may be less likely to happen to those who better adhere to a set of lifestyle behaviors and factors such as maintaining a healthy weight and controlling blood pressure and cholesterol.

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Heart Attack Heart attacks Blood Pressure Stroke 40

Frontiers in Cardiovascular Medicine

DECEMBER 5, 2024

Modified low-density lipoproteins (LDL), such as oxidized LDL (oxLDL), small dense LDL (sdLDL), and electronegative LDL [LDL(-)], are capable of triggering the atherogenic process, favoring the subendothelial accumulation of cholesterol and promoting inflammatory, proliferative, and apoptotic processes characteristic of atherosclerotic lesions.

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Circulation Stroke Strokes Atherosclerosis 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A91-A91, February 1, 2025. The acute phase of ischemic stroke triggers a complex cascade of cellular responses in the brain and the immune system. Previous studies show that ischemic stroke induces microglial lipid accumulation from 3d to 7d after stroke, linked to pro-inflammatory activation.

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Stroke Strokes Cholesterol Circulation 40

Science Daily - Stroke

JULY 7, 2023

A novel molecular pathway to explain how a mutation in the gene ACTA2 can cause individuals in their 30s -- with normal cholesterol levels and no other risk factors -- to develop coronary artery disease has now been identified,

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Coronary Artery Disease Cholesterol Risk Factors 40

Journal of the American Heart Association

JANUARY 31, 2024

BackgroundIschemic conditioning‐induced cardioprotection was attenuated by dyslipidemia in some animal and clinical studies, which is not investigated in patients with stroke. A significantly higher proportion of modified Rankin Scale score 0 to 1 was identified in the RIC versus control subgroup across the normal‐total cholesterol group (69.9%

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Cholesterol Stroke Strokes Outcomes 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page A115-A115, February 1, 2025. AXL+microglia possessed stronger phagocytosis capacity and wrapped myelin debris most obviously in striatum after stroke. Background:Ischemic white matter injury leads to long-term neurological deficits and lacks effective medication.

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Stroke Strokes Cholesterol 40

Stroke Journal

NOVEMBER 9, 2023

Stroke, Volume 54, Issue 12 , Page 3182-3189, December 1, 2023. The identification of a variant in theHDAC9gene as a risk factor for large-artery atherosclerotic stroke, and subsequently coronary artery disease, has opened novel treatment pathways for stroke and more widely atherosclerotic disease.

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Stroke Strokes Atherosclerosis Coronary Artery Disease 40

Stroke Journal

JANUARY 30, 2025

Stroke, Volume 56, Issue Suppl_1 , Page ATP380-ATP380, February 1, 2025. Although progress has been made, the role of lipid metabolism following stroke remains unclear. Recent research on neurodegenerative diseases has highlighted a pathophysiological cascade characterized by abnormal lipid accumulation within the brain.

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Stroke Strokes Pharmacology Cholesterol 40

All About Cardiovascular System and Disorders

APRIL 30, 2024

Maintaining normal blood pressure also reduces the risk of stroke and myocardial infarction. High density lipoprotein cholesterol in the blood increases with regular exercise. HDL is involved in reverse cholesterol transport from the blood vessels to the liver. Exercise is the only established way to increase HDL cholesterol.

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Exercise Heart Disease Blood Pressure Cholesterol 52

Stroke: Vascular and Interventional Neurology

NOVEMBER 7, 2023

Stroke: Vascular and Interventional Neurology, Ahead of Print. of the patients with LVO ischemic stroke. 2.75];P=0.012), low‐density lipoprotein cholesterol/10 mg/dL (OR, 0.863 [95% CI, 0.745–1.00];P=0.049), complete recanalization (OR, not calculable;P<0.001), and endovascular therapy (OR, 17.4 [95% 95 CI, 9.06–526];P<0.001).

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Stroke Strokes Risk Factors Cholesterol 40

Science Daily - Stroke

JULY 12, 2023

Such atherosclerotic plaques, which are formed by the build-up of fatty and cholesterol deposits, constitute a major cause of heart attacks. In a major study, researchers have discovered a link between the levels of certain bacteria living in the gut and coronary atherosclerotic plaques.

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Heart Attack Heart attacks Plaque Cholesterol 69