New Mexico researchers develop cholesterol vaccine
Becker's Hospital Review - Cardiology
DECEMBER 14, 2023
Researchers at UNM School of Medicine have developed a new LDL cholesterol vaccine that is tested on mice and monkeys with positive results.
New genetic risk score identifies individuals at risk for heart disease who may benefit most from cholesterol-lowering therapies
Science Daily - Heart Disease
FEBRUARY 26, 2025
Atherosclerosis, or the buildup of plaque in the arteries, develops when low-density lipoprotein cholesterol (LDL-C) enters the blood vessel walls through dysfunctional endothelial cells (EC), leading to the formation of plaques.
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Research reveals new insights about how 'bad' cholesterol works in the body
Medical Xpress - Cardiology
DECEMBER 11, 2024
National Institute of Health (NIH) scientists have made a significant breakthrough in understanding how "bad" cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body.
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How AI-Powered ECG Analysis is Advancing Cardiometabolic Research: Our Latest Study with University Hospital Basel
Cardiomatics
FEBRUARY 5, 2025
At Cardiomatics, we are committed to advancing cardiac research with AI-driven ECG analysis. These commonly used anti-inflammatory drugs often cause insulin resistance, high cholesterol, and muscle loss. A key focus of the research was heart rate variability (HRV)analyzed using our AI-powered ECG technology.
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New technology 'sees' how cholesterol causes heart attacks
Medical Xpress - Cardiology
DECEMBER 31, 2024
government's premier research body has made an important discovery that could help create new drugs to lower "bad" cholesterol, and hopefully prevent heart attacks and stroke.
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New insights about how 'bad' cholesterol works in the body
Science Daily - Heart Disease
DECEMBER 11, 2024
Scientists have made a significant breakthrough in understanding how 'bad' cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body.
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Unexplained changes in cholesterol may help identify older adults at risk for dementia
American Heart News - Heart News
NOVEMBER 11, 2024
Research Highlights: A study of older adults in Australia and the U.S. indicates that cholesterol levels that fluctuate significantly from year to year without a change in medication may someday help to identify those with a higher risk of developing.
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Scientists make surprising discovery pinpointing when good cholesterol becomes harmful
Science Daily - Heart Disease
DECEMBER 19, 2024
Researchers have discovered that certain components of so-called 'good' cholesterol -- high-density lipoproteins (HDL) -- may be associated with an increased prevalence of cardiovascular disease.
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High cholesterol was twice as prevalent among American Indian teens and young adults
American Heart News - Heart News
MARCH 8, 2024
Research Highlights: A study of more than 1,400 people in U.S. tribal communities found that high cholesterol was twice as prevalent among American Indian adolescents and young adults compared to the overall U.S. population. The study also noted that.
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Call for a consensual definition of dyslipidemia in coronary angiography trials
Frontiers in Cardiovascular Medicine
FEBRUARY 4, 2025
We listed definitions and their references in the 258 articles the research found. A systematic search of coronary angiography studies focusing on dyslipidemia was conducted. Out of the 258 articles retrieved in the search, 52 studies (20%) provided a definition of dyslipidemia, and 20 (8%) mentioned the source.
Researchers Find ApoB Test May be More Accurate Measure of Heart Disease Risk
DAIC
AUGUST 15, 2024
13, 2024 – The traditional lipid panel may not give the full picture of cholesterol-related heart disease risk for many Americans, according to a study led by UT Southwestern Medical Center researchers and published in JAMA Cardiology. Ann Marie Navar, M.D., tim.hodson Thu, 08/15/2024 - 10:32 Aug. population. Eric Peterson, M.D.,
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Novel PCSK9 Inhibitor Cut LDL Cholesterol Levels by More Than Half
DAIC
APRIL 7, 2024
milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo.
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Vitamin once recommended for lowering cholesterol linked to CV disease
Becker's Hospital Review - Cardiology
FEBRUARY 20, 2024
Niacin , a common B vitamin once recommended to patients as a way to help lower cholesterol, has been linked to cardiovascular disease, Cleveland Clinic researchers announced Feb.
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High cholesterol levels at a young age significant risk factor for atherosclerosis
Science Daily - Heart Disease
SEPTEMBER 4, 2024
Our risk of developing atherosclerosis -- 'furring' of the arteries -- can begin much earlier in life than was previously thought, highlighting the need to keep cholesterol levels low even when we are young, new research has discovered.
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Remnant cholesterol, lipid ratios, and the severity of coronary artery lesions: a retrospective cohort study in patients with coronary heart disease
Frontiers in Cardiovascular Medicine
MARCH 9, 2025
BackgroundEmerging genetic and observational evidence indicates that remnant cholesterol (RC) is a significant residual risk factor for cardiovascular diseases. Our study also examined the relationship between inconsistencies in RC and non-high-density lipoprotein cholesterol (non-HDL-C) levels and the severity of coronary artery stenosis.
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A protein at the heart of heart disease
Science Daily - Heart Disease
FEBRUARY 3, 2025
Low-density lipoproteins (LDL) -- commonly known as bad cholesterol -- have long been on scientists' radar as a major contributor to heart disease. Researchers have now revealed the specific shape and structure of one of the body's most important yet complicated proteins: ApoB100. That is, until now.
Surprising discovery pinpoints when good cholesterol becomes harmful
Medical Xpress - Cardiology
DECEMBER 19, 2024
Houston Methodist researchers have discovered that certain components of so-called "good" cholesterolhigh-density lipoproteins (HDL)may be associated with an increased prevalence of cardiovascular disease.
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Live well, think well: Research shows healthy habits tied to brain health
Science Daily - Heart Disease
OCTOBER 23, 2024
In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a new study.
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Clinical trial finds RNA inhibitor effectively reduces 'bad cholesterol' in patients with cardiovascular disease
Medical Xpress - Cardiology
FEBRUARY 12, 2025
The RNA inhibitor olpasiran significantly reduces a type of "bad cholesterol" that's associated with a high risk of cardiovascular events, according to results from an analysis by a Mount Sinai researcher of a Phase II trial.
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Ezetimibe Plus Statins Equals Better Outcomes
CardiacWire
MARCH 26, 2025
However, not everyone with high cholesterol benefits from statins, leading many drug developers to focus on novel ways to lower LDL-C levels. Statins are one of the most prescribed drugs in the U.S., with over 25% of all adults 40 and up taking them. of patients with high LDL-C were on ezetimibe.
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Influence of remnant lipoprotein particle cholesterol on non-target lesions progression in patients undergoing percutaneous coronary intervention
Frontiers in Cardiovascular Medicine
DECEMBER 9, 2024
BackgroundLow-Density Lipoprotein Cholesterol (LDL-C) is the primary lipid therapy target for coronary artery disease (CAD) patients after percutaneous coronary intervention (PCI). Employing Multivariate Cox regression analysis, we assessed the correlation between RLP-C and NTLs progression.
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Replacing other snacks with pecans may improve cholesterol, diet quality
Medical Xpress - Cardiology
MARCH 17, 2025
Switching daily snack foods to pecans improved cholesterol levels and enhanced overall diet quality, according to a new study by researchers in the Penn State Department of Nutritional Sciences.
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ACCEL Lite: How Low and How Fast Should We Go with LDL Cholesterol?
American College of Cardiology
MARCH 11, 2025
Douglas Weaver and Kausik Ray delve into the importance of individualized cholesterol management. They discuss the latest research, the benefits of aggressive LDL reduction, and how tailoring treatment plans can help optimize heart health while minimizing risks. In this interview, Drs.
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New research finds ketogenic diet-induced high cholesterol does not predict heart disease
Medical Xpress - Cardiology
APRIL 7, 2025
The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, in collaboration with researchers across multiple institutions, has published a new study that challenges the long-held belief that high cholesterol correlates and even directly causes coronary artery disease, or plaque buildup in the arteries in metabolically healthy (..)
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2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association
Circulation
JANUARY 27, 2025
METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.
Avocados reduces Cholesterol!!
Heart 2023 Conference
MAY 9, 2022
Despite this, including them to a person’s food regimen can assist raise “suitable” ldl cholesterol degrees. However, they'll now no longer assist decrease “awful” ldl cholesterol with out extra food regimen changes. Some declare it could additionally decrease low-density lipoprotein (LDL) ldl cholesterol, called awful ldl cholesterol.
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Mexican American women less likely to take stroke prevention medications as prescribed
American Heart News - Heart News
DECEMBER 4, 2024
Research Highlights: An analysis of more than 1,300 stroke survivors found that women were less likely than their male counterparts to take medications, such as cholesterol-lowering statins and blood thinning medications to prevent blood clots, to.
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Link between high levels of niacin -- a common b vitamin -- and heart disease, study suggests
Science Daily - Heart Disease
FEBRUARY 19, 2024
Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease.
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Association of cumulative non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with the risk of cardiometabolic disease
Frontiers in Cardiovascular Medicine
NOVEMBER 19, 2024
BackgroundOne measurement of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) is considered to be associated with insulin resistance and cardiovascular disease (CVD) risk.
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Cholesterol test completion triples when tests are automatically pre-ordered: Study
Medical Xpress - Cardiology
JANUARY 30, 2025
A study conducted by researchers at the Perelman School of Medicine at the University of Pennsylvania found that by pre-ordering lipid panelsthe tests that can indicate high cholesterol and help predict stroke and heart disease riskclinicians could significantly improve the rate of patients who get the tests done.
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Ground-breaking discovery could pave the way for new therapies to prevent cardiovascular disease and stroke
Science Daily - Heart Disease
NOVEMBER 13, 2023
Researchers have discovered the mechanism by which cholesterol in our diet is absorbed into our cells. This discovery opens up new opportunities for therapeutic intervention to control cholesterol uptake that could complement other therapies and potentially save lives.
New medication given every 1-3 months may slash stubborn high cholesterol
American Heart News - Heart News
NOVEMBER 12, 2023
Research Highlights: While currently available PCSK9 inhibitor medications to lower cholesterol must be administered every few weeks by injection, a new, investigational PCSK9 inhibitor called recaticimab safely lowered bad cholesterol more than 50%.
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52 Analysis forecasts more heart attacks and strokes under the new cardiovascular risk calculator tool
Medical Xpress - Cardiology
JULY 29, 2024
A recently unveiled cardiovascular disease risk calculator that measures a patient's risk for heart attack and stroke is better calibrated and more precise than its previous version, but if current treatment guidelines for cholesterol and blood pressure therapy remain unchanged, the new calculator may have unintended consequences, according to research (..)
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Researchers show cholesterol type can affect your heart attack risk
Medical Xpress - Cardiology
JULY 2, 2024
Vascular plaque. It starts with inflammation. Perhaps your blood pressure has been a little too high for a little too long, putting strain on your blood vessels.
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A single infusion of a gene-editing medicine may control inherited high LDL cholesterol
American Heart News - Heart News
NOVEMBER 12, 2023
Research Highlights: In an interim report from the first study in people, a single infusion of a gene-editing therapy significantly reduced bad cholesterol (LDL-C) in people at high risk of early heart attack due to an inherited form of high.
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Longitudinal changes in remnant cholesterol and the risk of cardiovascular disease
Cardiovascular Diabetology
JANUARY 1, 2025
The analyses of longitudinal changes in remnant cholesterol (RC) and cardiovascular disease (CVD) remains are limited. The objective of the study was to investigate the associations of longitudinal changes in.
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Impact of remnant cholesterol on short-term and long-term prognosis in patients with prediabetes or diabetes undergoing coronary artery bypass grafting: a large-scale cohort study
Cardiovascular Diabetology
JANUARY 7, 2025
Remnant cholesterol (remnant-C) contributes to atherosclerotic cardiovascular disease (ASCVD), particularly in individuals with impaired glucose metabolism. Patients with impaired glu.
Apolipoprotein B test may be more accurate measure of heart disease risk
Medical Xpress - Cardiology
AUGUST 14, 2024
The traditional lipid panel may not give the full picture of cholesterol-related heart disease risk for many Americans, according to a study led by UT Southwestern Medical Center researchers and published in JAMA Cardiology.
Cholesterol, high-density lipoprotein, and glucose index versus triglyceride–glucose index in predicting cardiovascular disease risk: a cohort study
Cardiovascular Diabetology
MARCH 9, 2025
A newer index, the Cholesterol, High-Density Lipopr. Cardiovascular disease (CVD) represents a significant global health challenge, characterized by high incidence rates and substantial morbidity and mortality.
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The triglyceride glucose: high-density lipoprotein cholesterol ratio is associated with coronary artery calcification evaluated via non-gated chest CT
Cardiovascular Diabetology
OCTOBER 23, 2024
Although triglyceride glucose (TYG) index and high-density lipoprotein cholesterol (HDL-c) are both associated with CAC, n. Coronary artery calcification (CAC) is a common risk factor of cardiovascular disease.
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Remnant cholesterol and the risk of aortic valve calcium progression: insights from the MESA study
Cardiovascular Diabetology
JANUARY 8, 2024
Remnant cholesterol (RC) is implicated in the risk of cardiovascular disease. However, comprehensive population-based studies elucidating its association with aortic valve calcium (AVC) progression are limited.
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New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs
Medical Xpress - Cardiology
FEBRUARY 1, 2024
A research team based at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) in Madrid and Aarhus University in Denmark has identified an important mechanism that can result in the regression, or shrinkage, of atherosclerotic plaques.
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66 Cluster of slightly unhealthy traits linked with earlier heart attack and stroke
Science Daily - Stroke
AUGUST 25, 2023
Middle-aged adults with three or more unhealthy traits including slightly high waist circumference, blood pressure, cholesterol and glucose have heart attacks and strokes two years earlier than their peers, according to new research.
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The relationship between serum HDL-cholesterol, cardiovascular disease and mortality in community-based people with type 2 diabetes: the Fremantle Diabetes Study phase 2
Cardiovascular Diabetology
OCTOBER 13, 2024
Older general population-based studies found an inverse association between serum HDL-cholesterol and both cardiovascular disease (CVD) events and mortality, but more recent data have suggested a U-shaped rela.
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