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Suboptimal Control of Small Dense Low‐Density Lipoprotein Cholesterol Is Associated With Coronary Plaque Progression: An Intravascular Ultrasound Study

Journal of the American Heart Association

BackgroundPlaque progression (PP) is critical between subclinical atherosclerosis and plaque rupture. Small dense lowdensity lipoprotein cholesterol (sdLDLC) is considered as the most atherogenic lipoprotein. Journal of the American Heart Association, Ahead of Print.

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Dyslipidemia in American Indian Adolescents and Young Adults: Strong Heart Family Study

Journal of the American Heart Association

We used carotid ultrasounds to detect plaque at baseline and follow‐up in 2006 to 2009 (median follow‐up=5.5 had low‐density lipoprotein cholesterol ≥160 mg/dL, which is higher than the recommended threshold for lifestyle or medical interventions in young adults of 20 to 39 years old. Lipids were measured after a 12‐hour fast.

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How To Reverse Coronary Artery Disease With Lifestyle Measures

Dr. Paddy Barrett

You cannot eliminate the plaque entirely, but multiple clinical trials have shown plaque regression using high-intensity cholesterol-lowering treatments, which I have discussed previously. All of these parameters are important and need to be considered when evaluating plaque regression. REVERSAL Investigators.

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Association of sdLDL-C With Incident Carotid Plaques With Stable and Vulnerable Morphology: A Prospective Cohort Study

Stroke Journal

BACKGROUND:Small dense low-density lipoprotein cholesterol (sdLDL-C) particles are more atherogenic than large and intermediate low-density lipoprotein cholesterol (LDL-C) subfractions. Incident carotid plaques and their vulnerability were detected by carotid ultrasound at follow-up (2021). Stroke, Ahead of Print.

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Abstract TP226: Analysis of the Association Between Lipoprotein(a) Levels and Carotid Plaque and Coronary Artery Calcium Using Health Checkup Data

Stroke Journal

Carotid ultrasound results were divided into two groups based on the presence or absence of plaque. Carotid plaque was observed in 1140 (43.5%) subjects and CACS>0 in 1172 (44.7%) subjects. Lp(a) levels were categorized into two groups: below 50 mg/dl and 50 mg/dl or higher. 1692 (64.6%) were male.

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Abstract 4142898: Marine N-3 Fatty Acids Improve Carotid Atherosclerosis in Diabetic Patients

Circulation

The primary outcome was the prevalence of carotid artery plaques assessed by ultrasound. Secondary outcomes included changes in NMR-derived lipoprotein subclasses and their mediation effects on carotid plaque. Fish oil supplementation was significantly associated with reduced prevalence of carotid plaques (P=0.023).

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How Does Exercise Prevent Heart Disease?

All About Cardiovascular System and Disorders

Plaque regression can be demonstrated by ultrasound evaluation of the carotids which are easily accessible. High density lipoprotein cholesterol in the blood increases with regular exercise. HDL is involved in reverse cholesterol transport from the blood vessels to the liver.