Remove Cholesterol Remove Plaque Remove Risk Factors
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Why Waiting Until Age 50 To Address Risk Factors For Heart Disease Is Too Late.

Dr. Paddy Barrett

The reason: They were accumulating plaque in their coronary arteries much earlier than their peers. You can’t have a heart attack if you don’t have plaque in your coronary arteries. And plaque in your coronary arteries is the result of exposure to risk factors over time. The answer: Risk Factors.

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Physiology Friday #199: High-Intensity Interval Training Reduces Coronary Artery Plaque

Physiologically Speaking

In this 6-month randomized controlled study, twice-weekly HIIT reduced coronary plaque volume, increased aerobic fitness, and improved body composition in adults with stable heart disease, suggesting benefits for cardiovascular disease progression. Does this greater plaque presence put athletes at a greater risk of CVD events?

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Suboptimal Control of Small Dense Low‐Density Lipoprotein Cholesterol Is Associated With Coronary Plaque Progression: An Intravascular Ultrasound Study

Journal of the American Heart Association

BackgroundPlaque progression (PP) is critical between subclinical atherosclerosis and plaque rupture. Small dense lowdensity lipoprotein cholesterol (sdLDLC) is considered as the most atherogenic lipoprotein. Journal of the American Heart Association, Ahead of Print.

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Dyslipidemia in American Indian Adolescents and Young Adults: Strong Heart Family Study

Journal of the American Heart Association

We used carotid ultrasounds to detect plaque at baseline and follow‐up in 2006 to 2009 (median follow‐up=5.5 had low‐density lipoprotein cholesterol ≥160 mg/dL, which is higher than the recommended threshold for lifestyle or medical interventions in young adults of 20 to 39 years old. Lipids were measured after a 12‐hour fast.

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Computed tomographic angiography measures of coronary plaque in clinical trials: opportunities and considerations to accelerate drug translation

Frontiers in Cardiovascular Medicine

The complex development of atherosclerosis manifests as intimal plaque which occurs in the presence or absence of traditional risk factors. For cardiovascular disease, only low-density lipoprotein cholesterol and blood pressure are approved as surrogates for cardiovascular disease.

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Study Finds Olezarsen Cuts Triglyceride Levels by About Half

DAIC

It is well known that high levels of low-density lipoprotein (LDL) cholesterol, known as the “bad” cholesterol, heighten cardiovascular risk. A total of 154 patients (median age 62 years, 42% women) with high triglyceride levels and other risk factors for cardiovascular disease participated in the study at 24 sites in the U.S.

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Abstract 47: Estimated Remnant Lipoprotein Particle Cholesterol, Very Low-Density Lipoprotein Cholesterol, and Incident Ischemic Stroke Risk - The Cardiovascular Health Study

Stroke Journal

Introduction:Serum remnant lipoprotein particle cholesterol (RLP-C), which includes very-low density lipoproteins (VLDL) and its lipolytic products, contributes to atherosclerotic plaque formation. Novel methods for estimating RLP-C and VLDL-cholesterol (VLDL-C) from a serum fasting lipid profile (FLP) have been proposed (Figure).1,2,3We