Physiologically Speaking

JULY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This irregular sleep pattern misaligns circadian rhythms and disrupts physiology. ICYMI: On Wednesday, I published my video interview with Dr. Andrew Koutnik. “The shorter your sleep, the shorter your life.”

Chronic Disease 64

Chronic Disease Physiology Atrial Flutter Atrial Fibrillation 64

Physiologically Speaking

DECEMBER 22, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

DECEMBER 22, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Clinically, about 1/3 of adults have metabolic syndrome — a cluster of conditions including abdominal obesity, high blood pressure, high blood glucose, high triglycerides, and low HDL cholesterol.

Exercise 52

Exercise Physiology Blood Pressure Cholesterol 52

Physiologically Speaking

JUNE 7, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Details about the sponsors of this newsletter including Examine.com and my book “VO2 Max Essentials ” can be found at the end of the post!

Exercise 52

Exercise Physiology Blood Pressure Outcomes 52

Physiologically Speaking

JANUARY 26, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. What if your calendar was the key to living a longer, healthier life? Health and time have always been two sides of the same coin, but we haven’t had the technology to bridge them until now.

Physiology 52

Physiology Diet Cardiovascular Disease BMI 52

Journal of the American Heart Association

APRIL 7, 2025

At age 32 years, participants underwent a physiological assessment, and CVH was estimated using Life's Essential 8 metrics: body mass index, blood pressure, cholesterol, glycated hemoglobin, sleep, smoking, and physical activity (diet not available).

Blood Pressure 45

Blood Pressure Diet Cholesterol Physiology 45

Dr. S. Venkatesan MD

MAY 26, 2024

LDL is potrayed as villian de-chief of atheroscerlois and CAD.But, LDL of about 100 to 160 mg concentration is in constant circulation, in a smooth manner serving other physiological vascular functions. 15272 LDL receptors, caveolae and cholesterol in endothelial dysfunction: oxLDLs accomplices or victims?

Pharmacology 45

Pharmacology Cholesterol Physiology Diabetes 45

Physiologically Speaking

NOVEMBER 8, 2023

Physiologically Speaking is a reader-supported publication. Cardiovascular Health 🫀 Intermittent fasting can lead to improvements in lipid profiles, including reduced levels of total cholesterol, low-density lipoprotein (LDL) cholesterol, and triglycerides.

Diet 52

Diet Cholesterol Physiology Blood Pressure 52

Dr. S. Venkatesan MD

OCTOBER 2, 2024

In physiological state ,it is amazing to note, how a single layer of endothelial cells is able to withstand a lifetime of vascular stress. After all, please remember much greater men like Abraham Lincoln and Mahatma Gandhi lived a stellar life , in the grand old era when no one knew what was cholesterol and lipids.” 2019.0211. )

Plaque 52

Plaque Atherosclerosis Education Cholesterol 52

Physiologically Speaking

FEBRUARY 23, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. Macrophages are unleashed to promote the buildup of plaque and cholesterol in the arteries (atherosclerosis). To receive new posts and support my work, consider becoming a free or paid subscriber.

Physiology 111

Physiology Atherosclerosis Diet Cardiovascular Disease 111

Physiologically Speaking

DECEMBER 15, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.”

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. This newsletter is brought to you by Examine.com — the best place on the internet for health and nutrition information — and my new eBook, “VO2 Max Essentials.”

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Journal of Clinical Investigation - Cardiology

FEBRUARY 15, 2024

Aster proteins mediate the nonvesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER). However, the importance of nonvesicular sterol movement for physiology and pathophysiology in various tissues is incompletely understood.

Diet 116

Diet Obesity Cholesterol Physiology 116

Physiologically Speaking

MARCH 6, 2024

Statins lower cholesterol. Exercise perturbs our entire physiology, and it’s this disruption of homeostasis, integrative crosstalk, and subsequent adaptations that lead to the immense health benefits achieved through physical activity. For one, drugs target single pathways or risk factors.

Exercise 92

Exercise Blood Pressure Risk Factors Physiology 92

Dr. Smith's ECG Blog

JANUARY 23, 2024

Other than being overweight and having an elevated cholesterol she was healthy. The physiologic reason for this — is thought to be the result of momentarily increased circulation from mechanical contraction arising from the "sandwiched in" QRS complex. She was feeling fine prior to the last seven days. There was no chest pain.

Tachycardia 107

Tachycardia Arrhythmia Heart Disease Sudden Cardiac Death 107

MIBHS

MAY 15, 2024

While factors like high blood pressure, high cholesterol, obesity, and smoking affect both men and women, certain conditions like diabetes, metabolic syndrome, and mental stress tend to pose a higher risk for women. Hormonal changes, particularly during menopause, also play a significant role, altering women’s cardiovascular health.

Heart Disease 52

Heart Disease Chest Pain Risk Factors Blood Pressure 52

Physiologically Speaking

AUGUST 2, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. And we know that stress — both psychological and physiological — is a risk factor for CVD. Our thoughts and our neural activity (which our thoughts are after all) are reflected in our physiology, and vice-versa.

Exercise 111

Exercise Physiology Cardiovascular Disease Blood Pressure 111

Physiologically Speaking

MAY 3, 2024

Welcome to the Physiology Friday newsletter. Physiologically Speaking is a reader-supported publication. ICYMI On Wednesday, I published a post discussing the different metabolic effects of the ketogenic diet and exogenous ketones during exercise.

Exercise 95

Exercise Physiology Research Kidney Disease 95

Journal of Clinical Investigation - Cardiology

MARCH 17, 2025

In mammalian cells cholesterol can be synthesized endogenously or obtained exogenously through lipoprotein uptake. Plasma membrane (PM) is the primary intracellular destination for both sources of cholesterol, and maintaining appropriate membrane cholesterol levels is critical for cellular viability.

Cholesterol 87

Cholesterol Physiology 87

Dr. S. Venkatesan MD

JANUARY 8, 2024

10kg) Out of which just 250 mg of cholesterol is streaming in blood. We must understand Fat, lipid and cholesterol are different entities. While the total body seems to do little in determining cholesterol levels, what is more scientifically shocking is slope of the curve between blood LDL levels and plaque burden is rarely linear.

Cholesterol 52

Cholesterol Atherosclerosis Plaque Physiology 52

Dr. Paddy Barrett

OCTOBER 24, 2023

Not everyone who meets the criteria for metabolic syndrome will become diabetic, but falling into this category means you share much of the same underlying physiology. But our physiology does not care. Subscribe now You have to think of this as a matter of degree. This is about an overall lifestyle approach. Impressive findings.

Diabetes 52

Diabetes Cancer Exercise Cardiovascular Disease 52

Dr. Malcolm Kendrick

MARCH 6, 2025

After all, most people are convinced that a raised cholesterol level causes heart disease, and there appears to be a vast mountain of data to support this hypothesis. I have spent forty years studying this area, and I am absolutely certain that cholesterol (or LDL Low Density Lipoprotein) does not cause heart disease.

COVID-19 96

COVID-19 Blood Clot Heart Attack Heart attacks 96