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Obesity alters cholesterol homeostasis in regulatory T cells of visceral adipose tissue

Nature Reviews - Cardiology

Nature Reviews Cardiology, Published online: 28 January 2025; doi:10.1038/s41569-025-01129-y A new study shows how obesity can disrupt a cholesterol metabolism in a particular subset of metabolically protective regulatory T cells in visceral adipose tissue.

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Exploring Obesity and the Latest Advances in Weight Loss Drugs during Healthy Weight Week

Cardiometabolic Health Congress

In today’s society, the prevalence of obesity has become a significant concern. have obesity, and this rate has increased by more than 10 percentage points in the past two decades. Understanding the prevalence of obesity is crucial in comprehending why events like Healthy Weight Week are essential. of adults in the U.S.

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Body mass index impacts the lipid-lowing effects of statins in patients with type 2 diabetes

Frontiers in Cardiovascular Medicine

Patients were stratified into three groups: normal weight (BMI<24kg/m), overweight (24kg/m2BMI<28kg/m2), and obese (BMI28kg/m2). Overweight and obese patients were found to be younger than those with normal weight. Obese patients exhibited a remarkable 42.02% reduction in LDL levels (normal 27.45%, overweight 30.64%).

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2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation

METHODS:The AHA, through its Epidemiology and Prevention Statistics Committee, continuously monitors and evaluates sources of data on heart disease and stroke in the United States and globally to provide the most current information available in the annual Statistical Update with review of published literature through the year before writing.

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Living healthier, longer: The effect of risk factors on life expectancy

Medical Xpress - Cardiology

The five classic risk factors for cardiovascular disease are well knownsmoking, high blood pressure, high cholesterol, diabetes, and underweight or overweight/obesity. All increase the likelihood of heart ailments down the road.

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Association of triglyceride-glucose-related indices with adverse clinical outcomes in individuals with normal body mass index

Frontiers in Cardiovascular Medicine

Most research has focused on obese individuals, with limited exploration in those with a normal body mass index (BMI).MethodThis ConclusionThe study identified a link between TyG-related markers and negative outcomes in individuals with a normal BMI, indicating that insulin resistance exists even in non-obese populations.

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Cholesterol is not the only lipid involved in trans fat-driven cardiovascular disease

Science Daily - Heart Disease

This new insight into the flow of fats through the body points to new therapeutic targets for mitigating diseases like ASCVD, non-alcoholic fatty liver disease, obesity, diabetes, peripheral neuropathy, and neurodegeneration.