This site uses cookies to improve your experience. To help us insure we adhere to various privacy regulations, please select your country/region of residence. If you do not select a country, we will assume you are from the United States. Select your Cookie Settings or view our Privacy Policy and Terms of Use.
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Used for the proper function of the website
Used for monitoring website traffic and interactions
Cookie Settings
Cookies and similar technologies are used on this website for proper function of the website, for tracking performance analytics and for marketing purposes. We and some of our third-party providers may use cookie data for various purposes. Please review the cookie settings below and choose your preference.
Strictly Necessary: Used for the proper function of the website
Performance/Analytics: Used for monitoring website traffic and interactions
government's premier research body has made an important discovery that could help create new drugs to lower "bad" cholesterol, and hopefully prevent heartattacks and stroke.
A recently unveiled cardiovascular disease risk calculator that measures a patient's risk for heartattack and stroke is better calibrated and more precise than its previous version, but if current treatment guidelines for cholesterol and blood pressure therapy remain unchanged, the new calculator may have unintended consequences, according to research (..)
milla1cf Sun, 04/07/2024 - 18:09 April 7, 2024 — Among patients at high or very high risk for a heartattack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or “bad” cholesterol, levels by more than half on average, compared with a placebo.
Middle-aged adults with three or more unhealthy traits including slightly high waist circumference, blood pressure, cholesterol and glucose have heartattacks and strokes two years earlier than their peers, according to new research.
Researchers have identified a new pathway that contributes to cardiovascular disease associated with high levels of niacin, a common B vitamin previously recommended to lower cholesterol. The team discovered a link between 4PY, a breakdown product from excess niacin, and heart disease.
Vascular plaque. It starts with inflammation. Perhaps your blood pressure has been a little too high for a little too long, putting strain on your blood vessels.
The Minneapolis Heart Institute Foundation (MHIF) is presenting leading research focused on trends in ST-elevation myocardial infarction (STEMI), the most severe form of a heartattack, at the American College of Cardiology’s Annual Scientific Session (ACC.24), 24), being held April 6-8 in Atltanta, GA.
Research Highlights: In an interim report from the first study in people, a single infusion of a gene-editing therapy significantly reduced bad cholesterol (LDL-C) in people at high risk of early heartattack due to an inherited form of high.
In a major study, researchers have discovered a link between the levels of certain bacteria living in the gut and coronary atherosclerotic plaques. Such atherosclerotic plaques, which are formed by the build-up of fatty and cholesterol deposits, constitute a major cause of heartattacks.
New research details the first oral drug for the treatment of a type of high cholesterol -- called Lp(a) -- that is a potentially more dangerous version of the so called 'bad' cholesterol, LDL, because it is stickier and may be more likely to cause blockages and blood clots in your arteries.
You cannot eliminate the plaque entirely, but multiple clinical trials have shown plaque regression using high-intensity cholesterol-lowering treatments, which I have discussed previously. In general, the more calcified or fibrous a plaque is, the less dangerous it is, as it is less likely to rupture and cause a heartattack.
Is HIIT too dangerous for individuals after heart surgery or who’ve suffered a heartattack? Researchers also measured body mass index, waist circumference, blood glucose (HbA1c) and blood lipids. Does intense exercise adversely affect coronary plaque? A maximal exercise test (i.e., Results There was a 1.2%
reduction in low-density lipoprotein (LDL) cholesterol, on average, six months after starting treatment. Statins are a mainstay of heart disease prevention, yet experts estimate that less than half of patients who are eligible to receive the drugs are currently taking them.
High levels of triglycerides and the lipid particles on which they are carried in the blood can contribute to the formation of “plaques” in the arteries that impede blood flow and can lead to heartattacks and strokes. Patients’ average triglyceride level at baseline was about 900 mg/dL.
I do apologise for being direct, but this issue is one of the most frequent barriers I encounter to initiating cholesterol-lowering therapy. A therapy that has been proven repeatedly to reduce the probability of heartattacks and strokes in multiple double-blind randomised controlled studies 1. Let’s break this down.
Introduction:Xylitol, a sugar alcohol with a global market estimated at 161,500 metric tons, has been linked to increased thrombosis and risk of stroke and heartattack. fasting blood glucose was 103 13 mg/dL, HDL cholesterol was 49 10 mg/dL, and triglycerides were 173 63 mg/dL. The mean BMI was 35.2
Eighty percent of heartattacks and strokes are preventable. partially because its key risk factor, high blood pressure, is a ‘silent killer,’ and most patients have no symptoms before their first heartattack or stroke. The monitor and app recorded blood pressure, heart rate, and the appearance of irregular heartbeat.
milla1cf Sat, 04/06/2024 - 18:32 April 6, 2024 — The first trial of a novel strategy for removing cholesterol from patients’ arteries did not reduce the risk of death, heartattack or stroke within three months of a prior heartattack, according to research presented at the American College of Cardiology ’s Annual Scientific Session.
Understanding the Genetic Connection to Heart Disease Your genetic makeup plays a vital role in shaping your heart health. Genes influence various biological processes, including cholesterol metabolism, blood pressure regulation, and the strength and structure of your heart and blood vessels. How Do Genetic Factors Work?
The first trial of a novel strategy for removing cholesterol from patients’ arteries did not reduce the risk of death, heartattack or stroke within three months of a prior heartattack, according to research presented at ACC.24, 24, the American College of Cardiology Annual Annual Scientific Session.
These findings are concordant with prior research that demonstrates the low-dose colchicine, 0.5 mg can prevent heartattack and stroke in high-risk patients with established cardiovascular disease. mg improved coronary plaque stability in patients with acute coronary syndrome.
PCI is commonly used to open blocked arteries to treat significant myocardial ischemia , which occurs when the heart muscle does not get enough oxygenated blood. The idea behind preventive PCI is that a stent could help to stabilize a high-risk plaque lesion and thus reduce its risk of rupture before a heartattack occurs.
With the ultimate goal that all of my patients (Myself included) live a long and healthy life and die with, not from, heart disease. The steps to implementing this process result from over a decade of research. The Heart Health Formula covers everything you need to know about understanding and reducing the risk of heart disease.
Clinicians currently use two separate risk models to assess patients’ chances of having heartattacks , strokes , and other major cardiovascular events. The researchers used a dataset covering nearly 10,000 participants over two decades to develop the new model, and a separate dataset to validate its accuracy.
They will also selectively support clinical research involving the CaRi-Heart technology for coronary inflammation diagnostics and LODOCO 0.5 Caristo shares Agepha Pharma’s passion for fighting coronary inflammation, which is one of the primary drivers of heartattack risks,” said Frank Cheng , CEO of Caristo Diagnostics.
By silencing the LPA gene, the levels of Lp(a) are lowered, which in turn is expected to lower the risk of heart diseases, heartattacks and strokes. “We A major risk factor for cardiovascular disease is a high blood level of low-density lipoprotein cholesterol (LDL-C), or “bad cholesterol,” that can be treated with statins.
3 Patients with ASCVD are at a higher risk for major adverse cardiovascular events (MACE) including heartattack or myocardial infarction (MI), stroke, and cardiovascular (CV) death.4 7 Research has shown inflammation plays a significant role in the development of atherosclerosis and ASCVD,8-10 and even the formation of plaque.11
A new peer-reviewed study published in the Journal of the American Heart Association , JAHA, found that Hello Heart’s digital heart health program was associated with reductions in blood pressure (BP), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and weight. statins). . -
The findings – published this week in the Journal of the American College of Cardiology — could fuel advocacy for a paradigm shift in clinical heart health guidelines to address cardiovascular risk factors at an earlier age in childhood cancer survivors.
The results were calculated using a new, proposed risk prediction scale for heart failure specifically for American Indian adults. and a researcher at Columbia University’s Mailman School of Public Health in New York City. and a researcher at Columbia University’s Mailman School of Public Health in New York City.
These findings are concordant with prior research that demonstrates the low-dose colchicine, 0.5 mg can prevent heartattack and stroke in high-risk patients with established cardiovascular disease. mg improved coronary plaque stability in patients with acute coronary syndrome.
The study assessed the prevalence of CVD (heartattack, angina pectoris, coronary heart disease, other heart conditions, or stroke) and LE8 risk factors: insufficient physical activity (PA), nicotine exposure, sleep duration, obesity, physician-diagnosed high cholesterol, diabetes, and hypertension.
In November 2023 the AHA launched the PREVENT risk equations , which take into account a wider range of cardiovascular, kidney, and metabolic health measures to estimate 10- and 30-year risks of heartattack, stroke, and heart failure. vs. 8%).
Basically she had been to see her GP and because her cholesterol was found to be a little on the higher side, she was being strongly advised by her GP to take a Statin. High Cholesterol is not really a condition unless it impacts on the patient’s quality of life or length of life. This is where data from research studies can help.
People at risk of cardiovascular disease would have their cholesterol levels checked. The aim is to reduce death and damage from nasty things such as heartattacks and strokes. With diabetes, the aim is also to reduce heartattacks and strokes… additionally kidney failure, and amputations, and blindness.
CT coronary angiography, in addition to a CT CAC, is arguably the best test for estimating whether someone has evidence of coronary artery disease and what that means for their near-term risk of a heartattack. Having no evidence of plaque on both of these tests reflects a very low risk of a heartattack in the next five to ten years.
There are only a few elite academic trialist groups capable of running large trials and there’s ample reason to be suspicious about the nexus that has developed between academia and the pharmaceutical companies that shower them with cash to hopefully get a positive study result and pay off the pharmaceutical research investment manifold.
Pretty exhaustive research there, Barney. In my opinion, or should I say ‘allegedly’ what actually happened here was that Barney Calman had heard from various cardiology experts that cholesterol and statin ‘deniers’ were causing people to stop taking their drugs. Based on … a fly cover. Sorry, I know the answer to that.
The aim is to restore proper blood flow to the heart, alleviating symptoms like chest pain (angina) and reducing the risk of heartattacks. Additionally, the positive effects on heart health following coronary artery bypass surgery may alleviate the stress and anxiety caused by heart disease, which can also contribute to ED.
Brad notes that his primary care physician told him he was young, fit, and had a low bad cholesterol (LDL) and needed a calcium scan rather than a heart flow scan. Subscribe for free to receive new posts and support my work. Question 1. Does Brad need a calcium scan?
Getty Images milla1cf Mon, 04/29/2024 - 13:06 April 29, 2024 — Women with heart disease are less often treated with cholesterol-lowering drugs than men, according to research presented today at ESC Preventive Cardiology 2024 , a scientific congress of the European Society of Cardiology ( ESC ).1 80 years or older).
Researchers said the study underscores the importance of recognizing and addressing early warning signs of heart disease risk in women as they lose the protective effects of estrogen after menopause. A higher CAC score indicates a higher risk of a heartattack or other cardiac events.
Food and Drug Administration ( FDA ) has approved an additional indication for Wegovy ( semaglutide ) to reduce the risk of major cardiovascular events such as death, heartattack, or stroke in adults with known heart disease and with either obesity or overweight along with a reduced calorie diet and increased physical activity.
With that in mind, let's see what the research says about supplements and heart health. A recent systematic review and meta-analysis examined a range of commonly used supplements and whether they improved cardiovascular risk factors like blood pressure and cardiovascular events such as heartattacks and stroke.
We organize all of the trending information in your field so you don't have to. Join thousands of users and stay up to date on the latest articles your peers are reading.
You know about us, now we want to get to know you!
Let's personalize your content
Let's get even more personalized
We recognize your account from another site in our network, please click 'Send Email' below to continue with verifying your account and setting a password.
Let's personalize your content