Remove Cholesterol Remove Dementia Remove Stroke
article thumbnail

LDL Cholesterol Lowering: Is There a Risk for Dementia and Hemorrhagic Stroke?

American College of Cardiology

Reduction in low-density lipoprotein cholesterol (LDL-C) levels has consistently demonstrated a reduced risk of atherosclerotic cardiovascular disease (ASCVD). There is extensive evidence from randomized trials that demonstrates the effectiveness of lipid-lowering agents in reducing ASCVD-related events.

article thumbnail

Do Statins Cause Dementia?

Dr. Paddy Barrett

I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.

article thumbnail

Live well, think well: Research shows healthy habits tied to brain health

Science Daily - Heart Disease

In middle-aged people, having risk factors like blood pressure, blood sugar and cholesterol that are not well-controlled combined with not following certain healthy habits including exercise, diet and sleep, are linked to a higher risk of stroke, dementia or depression later in life, according to a new study.

article thumbnail

Use of lipid-lowering therapy after ischaemic stroke and expected benefit from intensification of treatment

Open Heart

Objectives Elevated low-density lipoprotein cholesterol (LDL-C) increases the risk of recurrent cardiovascular disease (CVD) events. We examined use of lipid-lowering therapy (LLT) following ischaemic stroke, and estimated benefits from guideline-based up-titration of LLT. and women (coefficient –5.1 to –0.9)

Strokes 52
article thumbnail

Abstract WP320: Microemboli Model of Vascular Cognitive Impairment/Dementia (VCID) Presents With Long-Term Brain Tissue Hypoxia: Relevance to Endothelin-1 (ET-1)

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWP320-AWP320, February 1, 2024. At 10 weeks after the onset of diabetes, control and diabetic rats received cholesterol crystal ME (40-70 μm) injections and were monitored for 16 weeks. Diabetes doubles the risk of VCID but the underlying reasons remain unclear.

article thumbnail

Abstract WMP21: Life's Essential 8 and Brain Health Clinical Outcomes in Middle-Aged Adults

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page AWMP21-AWMP21, February 1, 2024. We excluded participants with stroke, dementia, or late-life depression (LLD) at baseline. The outcome of interest was a composite of stroke, dementia, or LLD.

article thumbnail

Abstract 10: Enhanced Benefits of the Life's Essential 8 in APOE Epsilon 4 Carriers

Stroke Journal

Stroke, Volume 55, Issue Suppl_1 , Page A10-A10, February 1, 2024. While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population. Our outcome was a composite of stroke, TIA or MI.