Dr. Paddy Barrett

SEPTEMBER 19, 2023

I am going to start with the answer to the question of whether statins cause dementia and then provide the details backing up my answer. Statins do not cause dementia. But if you are someone who thinks that statins do cause dementia and you need to see the evidence to refute that claim, then read on. The answer is: No.

Dementia 52

Dementia Cholesterol Biomarkers Coronary Artery Disease 52

Medical Xpress - Cardiology

OCTOBER 24, 2024

If untreated, dyslipidemia, especially high levels of LDL cholesterol ("bad" cholesterol), increases the risk of myocardial infarction, cerebral infarction, and dementia. Therefore, it is crucial to visit a medical institution and take appropriate measures when dyslipidemia is detected during a health checkup.

Myocardial Infarction 40

Myocardial Infarction Cholesterol Dementia 40

Dr. Paddy Barrett

AUGUST 22, 2023

Being a carrier of the APOE4 gene variant is associated with higher rates of the most common type of dementia, late-onset dementia. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. Of those with late-onset dementia, up to 65% are carriers of the APOE4 gene variant 1. What to do?

Cholesterol 52

Cholesterol Dementia Coronary Artery Disease Cardiovascular Disease 52

Dr. Paddy Barrett

NOVEMBER 8, 2024

Only when you have a clear idea of those three factors can you decide whether or not to take a medication to lower your LDL cholesterol. I use statins in the question posed above because that is what most people think and, in fact, what they will start with when looking to lower their LDL cholesterol with a medication. Not zero risk.

Cholesterol 130

Cholesterol Plaque Heart Attack Heart attacks 130

Stroke Journal

FEBRUARY 1, 2024

At 10 weeks after the onset of diabetes, control and diabetic rats received cholesterol crystal ME (40-70 μm) injections and were monitored for 16 weeks. Another cohort received isosorbide mononitrate (ISMN, 75 mg/kg/day) and cilostazol (CZL, 60 mg/kg/day). Behavioral tests included novel object recognition (NOR) and Y-maze.

Dementia 40

Dementia Diabetes Cholesterol Stroke 40

Open Heart

APRIL 22, 2022

Objectives Elevated low-density lipoprotein cholesterol (LDL-C) increases the risk of recurrent cardiovascular disease (CVD) events. Patients with prestroke dementia and cardioembolic stroke aetiology were less likely to receive LLT. Results At discharge, 92% received LLT (97% statin monotherapy). and women (coefficient –5.1

Stroke 52

Stroke Strokes Cholesterol Dementia 52

Stroke Journal

JANUARY 30, 2025

Background:Vascular cognitive impairment (VCI) is the second most frequent subtype of dementia following Alzheimer's disease. MicroRNAs (miRNAs) play critical roles in the pathologies of cerebral ischemia and dementia. However, the underlying mechanism has not been fully understood and there is no effective treatment for VCI.

Dementia 40

Dementia Cholesterol Ischemia Stroke 40

Stroke Journal

FEBRUARY 1, 2024

We excluded participants with stroke, dementia, or late-life depression (LLD) at baseline. The exposure of interest was the LE8 score, a validated tool that captures the LE8 components (blood pressure, glucose, and cholesterol, body mass index, smoking, physical activity, diet, and sleep duration), organized in 3 categories.

Outcomes 40

Outcomes Dementia Blood Pressure Public Health 40

Stroke Journal

JANUARY 30, 2025

Background:PCSK9, a key regulator of cholesterol metabolism, has been implicated in atherosclerosis. However, its potential role in vascular cognitive impairment and dementia (VCID) remains elusive. Stroke, Volume 56, Issue Suppl_1 , Page ADP14-ADP14, February 1, 2025.

Diet 40

Diet Dementia Atherosclerosis Cholesterol 40

Dr. Paddy Barrett

FEBRUARY 23, 2024

Advanced cholesterol testing. Evaluating The Benefit Of Reducing Cardiovascular Risk AND Other Major Diseases, Including Cancer and Dementia. The Heart Health Formula is a video course covering everything you need to know about how to prevent heart disease. What causes heart disease. What tests you need to do.

Heart Disease 59

Heart Disease Best Practices Dementia Cholesterol 59

Stroke Journal

FEBRUARY 1, 2024

While the epsilon (ε) 4 variants within theAPOEgene have been extensively investigated as a risk factor for dementia and stroke,APOEε4 carriers have not been thoroughly studied as an at-risk population. Background:Adherence to the American Heart Association's Life’s Essential 8 (LE8) reduces the risk of cardiovascular disease.

Myocardial Infarction 40

Myocardial Infarction Blood Pressure Dementia Diet 40

Dr. Paddy Barrett

AUGUST 9, 2024

More than heart disease or cancer, the risk of dementia often creates much greater anxiety in the patients I see. And given that dementia is routinely in the top 5 leading causes of death, this concern is dually warranted. But can dementia be prevented? 14 Ways To Prevent Dementia. 14 Ways To Prevent Dementia.

Dementia 116

Dementia Blood Pressure Obesity Cholesterol 116

Dr. Paddy Barrett

FEBRUARY 13, 2024

Be satiating Low in sugar In a Carbohydrate/Fat Balance that suits your preference and doesn’t drive your LDL cholesterol through the roof. You get to choose how you are going to spend these 1,462 calories. My advice is: It should come from real foods. Subscribe now Now, you get to choose your restriction. Get tracking.

Diet 105

Diet Diabetes Exercise Kidney Disease 105

Cardiometabolic Health Congress

JUNE 7, 2024

He highlighted that cardiovascular health is essential for cognitive health, noting the common occurrence of vascular dementia. Ballantyne, MD , emphasized that while fellows may consider prevention “boring,” it is crucial for avoiding resource-intensive late-stage cardiovascular disease (CVD). Ballantyne, MD, FNLA , Robert A.

Cardiovascular Disease 59

Cardiovascular Disease Obesity Heart Disease Risk Factors 59

Dr. Paddy Barrett

NOVEMBER 1, 2024

Dementia: 64% reduction in risk. It still means you need to focus on good nutrition to achieve an optimal weight, and if you have other issues, such as high LDL cholesterol or high blood pressure, those may also need attention. Death from any cause: 53% reduction in risk. Death from heart disease: 51% reduction in risk.

Exercise 120

Exercise Heart Disease Quality of Life Blood Pressure 120

Dr. Paddy Barrett

JANUARY 23, 2024

Dementia Up to 40% of dementia cases could be prevented by focusing on modifiable risk factors 11. Those with high blood pressure from midlife have twice the risk of developing dementia over a 25-year follow-up 12. In most Western populations, dementia consistently ranks as a leading cause of death. Ann Glob Health.

Heart Disease 106

Heart Disease Blood Pressure Dementia Atherosclerosis 106

Dr. Paddy Barrett

MAY 3, 2024

What is a normal cholesterol? It usually takes many years of being exposed to an uncontrolled risk factor such as high blood pressure, high LDL cholesterol or diabetes. For those who have optimised their cardiovascular risk, their future risk of dementia and many cancers is also likely to reduce. What kind of diet should I eat?

Heart Attack 105

Heart Attack Heart attacks Blood Pressure Risk Factors 105

Dr. Paddy Barrett

SEPTEMBER 13, 2024

Understanding where you sit on this continuum is a key part of defining your future risk of heart disease but also dementia, and many cancers. Low HDL Cholesterol. The further along the line of insulin resistance you sit, the higher your risk of all the leading causes of death, including heart disease, dementia and many cancers 5.

Risk Factors 106

Risk Factors Heart Disease Dementia Diabetes 106

Dr. Paddy Barrett

JANUARY 16, 2024

Cardiovascular disease, cancer and dementia account for 60% of all deaths in the US. For those in the ‘Ideal’ category, they were 51% less likely to have either dementia or depression. And less diabetes means less of a driver of the three main leading causes of death - cardiovascular disease, cancer and dementia.

Cancer 97

Cancer Dementia Diabetes Cardiovascular Disease 97

Physiologically Speaking

DECEMBER 15, 2023

Specifically: - HDL cholesterol increases by 2–12 mg/dL - Total cholesterol decreases by 8 mg/dL - Triglycerides decrease by 7–13 mg/dL - LDL cholesterol may decrease by 10–13 mg/dL in adults at high cardiometabolic risk Weight and body composition Here’s where resistance exercise shines.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Physiologically Speaking

DECEMBER 15, 2023

Specifically: - HDL cholesterol increases by 2–12 mg/dL - Total cholesterol decreases by 8 mg/dL - Triglycerides decrease by 7–13 mg/dL - LDL cholesterol may decrease by 10–13 mg/dL in adults at high cardiometabolic risk Weight and body composition Here’s where resistance exercise shines.

Physiology 52

Physiology Exercise Blood Pressure Risk Factors 52

Stroke Journal

FEBRUARY 1, 2024

Introduction:Apolipoprotein E4 (ApoE4) allele is linked to increased LDL-Cholesterol, one of the main risk factors for intracranial large artery stenosis (ICAS). Whether these interactions influence the risk of stroke and dementia should be further investigated. Stroke, Volume 55, Issue Suppl_1 , Page AWP239-AWP239, February 1, 2024.

Stenosis 40

Stenosis Risk Factors Hypertension Dementia 40

Dr. Paddy Barrett

AUGUST 15, 2023

Insulin resistance is a core risk factor for the three leading causes of death: Cardiovascular Disease Cancer Dementia. mmol/l (150 mg/dl) Low HDL Cholesterol - (Males: <1.0 Insulin resistance is unlikely to be the primary causal factor for these conditions but is likely to be a major accelerant. mmol/l (39 mg/dl), Females < 1.3

Blood Pressure 52

Blood Pressure Risk Factors Diabetes Cholesterol 52

Dr. Malcolm Kendrick

OCTOBER 30, 2024

I, Dr Malcolm Kendrick, with or without other co-conspirators, would be accused of spreading misinformation about cholesterol and statins. The hypothesis that a raised cholesterol level causes heart disease [atherosclerotic cardiovascular disease (ASCVD)] is possibly the single most powerful idea in medicine. With thousands dying.

Cholesterol 145

Cholesterol Article Research Diet 145