AMS Cardiology

NOVEMBER 4, 2023

Understanding Peripheral Artery Disease Peripheral artery disease or PAD is a condition in which plaque builds up in the arteries that lead to the legs and feet. Exercise helps improve blood circulation, strengthen the heart and manage weight—all of which can help reduce the risk of PAD.

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Peripheral Arterial Disease Blood Pressure Diet Exercise 52

Journal of the American Heart Association

NOVEMBER 23, 2023

In apolipoprotein E−/−and wild‐type mice, BAR502, a dual GPBAR1/FXR agonist, alone or in combination with atorvastatin, reduced cholesterol and low‐density lipoprotein plasma levels, mitigated the development of liver steatosis and aortic plaque formation, and shifted the polarization of circulating leukocytes toward an anti‐inflammatory phenotype.

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Aortic Aneurysm Plaque Cholesterol 40

DAIC

MARCH 31, 2025

mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J. mg improved several measures of plaque volume changes over a period of 12 months in patients with stable coronary artery disease, Dr. Budoff continued.

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

MIBHS

FEBRUARY 28, 2025

Genes influence various biological processes, including cholesterol metabolism, blood pressure regulation, and the strength and structure of your heart and blood vessels. Specific genetic variants, such as those affecting cholesterol metabolism, can increase the likelihood of plaque buildup in the arteries.

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Genetic predisposition Heart Disease Cholesterol Blood Pressure 52

Dr. Paddy Barrett

SEPTEMBER 20, 2024

When we say heart disease, what we really mean is plaque in the artery wall. The fundamental cause of atherosclerosis is when a cholesterol particle crosses into the artery wall from the bloodstream, gets stuck, and sets off an inflammatory process 1. Every cholesterol particle has a protein marker called ApoB on its outside.

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Heart Disease Cholesterol Atherosclerosis Heart Attack 111

Dr. Paddy Barrett

OCTOBER 4, 2024

Everyone starts with no plaque in the coronary arteries, but over a long enough time frame, everyone develops plaque in their coronary arteries. By age 80, almost everyone will have evidence of advanced plaque in their coronary arteries, as defined by a cardiac CT 1. Plaque accumulation happens in stages. You got it.

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Heart Disease Plaque Cholesterol Risk Factors 105

MIBHS

OCTOBER 31, 2024

Coronary Artery Disease (CAD) CAD, which involves the narrowing or blockage of coronary arteries due to plaque buildup, can reduce blood flow to the heart. Regular physical activity can strengthen the heart and improve circulation. Monitor blood pressure and cholesterol levels regularly. Avoid smoking and limit alcohol intake.

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DAIC

MARCH 31, 2025

mg)has potential to directly reduce inflammation, which plays a substantial role in the formation and progression of atherosclerotic plaque leading to heart disease, said Matthew J. mg improved several measures of plaque volume changes over a period of 12 months in patients with stable coronary artery disease, Dr. Budoff continued.

Cardiovascular Disease 52

Cardiovascular Disease Plaque Coronary Artery Disease Heart Attack 52

Stroke Journal

JANUARY 21, 2024

BACKGROUND:Sex-specific differences in plaque composition and instability underscore the need to explore circulating markers for better prediction of high-risk plaques. Plaque stability was determined by gold-standard histological classifications. Adipokine, lipid, and immune profiling was conducted.

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DAIC

JANUARY 23, 2024

Atherosclerotic cardiovascular disease (ASCVD), caused by plaque buildup in arterial walls, is one of the leading causes of disability and death worldwide.1,2 7 Research has shown inflammation plays a significant role in the development of atherosclerosis and ASCVD,8-10 and even the formation of plaque.11 Circulation.

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Dr. Paddy Barrett

JANUARY 23, 2024

However, most adults will start to develop advanced plaque in their coronary arteries early in life. By age 66, more than half of all females will have evidence of advanced plaque in their coronary arteries, as seen on a CT calcium score. Coronary atherosclerosis, as evidenced by an abnormal CAC score, is a measure of advanced plaque.

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Heart Disease Blood Pressure Dementia Atherosclerosis 106

Frontiers in Cardiovascular Medicine

FEBRUARY 16, 2024

During atherogenesis, efficient autophagy is needed to facilitate efferocytosis and cholesterol efflux, limit inflammation and lipid droplet buildup, and eliminate defective mitochondria and protein aggregates. Introduction Atherosclerosis is a chronic inflammatory disease caused by the deposition of lipids within the artery wall.

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Atherosclerosis Plaque Diet Cholesterol 64

DAIC

JANUARY 25, 2024

Among patients who had no plaque and zero calcium at time of CCTA, those with the most abnormal CaRi-Heart test results experienced 11-fold higher risk for cardiac mortality and 5-fold higher risk for major adverse cardiac events (MACE) than those who had normal CaRi-Heart test results.

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Heart Attack Heart attacks Technology Cardiovascular Disease 110

DAIC

MAY 16, 2024

PAD is a serious, progressive cardiovascular disease primarily caused by a buildup of fatty plaque in the blood vessels, or atherosclerosis. This plaque narrows the blood vessels and reduces blood flow to the legs and feet, which may significantly impair physical function, walking performance and quality of life.

Peripheral Arterial Disease 105

Peripheral Arterial Disease Exercise Ischemia Quality of Life 105

Dr. Paddy Barrett

MAY 31, 2024

Heart disease, the build-up of plaque in the coronary arteries, typically starts years, if not decades, prior to an event. These noninvasive scans look directly at the coronary arteries rather than assessing for the risk factors for coronary artery disease eg LDL cholesterol, high blood pressure etc. As the line goes, “No Plaque.

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Heart Disease Plaque Heart Attack Heart attacks 96