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2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation

Circulation, Ahead of Print.

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Atherogenic circulating lipoproteins in ischemic stroke

Frontiers in Cardiovascular Medicine

Modified low-density lipoproteins (LDL), such as oxidized LDL (oxLDL), small dense LDL (sdLDL), and electronegative LDL [LDL(-)], are capable of triggering the atherogenic process, favoring the subendothelial accumulation of cholesterol and promoting inflammatory, proliferative, and apoptotic processes characteristic of atherosclerotic lesions.

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2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association

Circulation

Circulation, Ahead of Print.

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Abstract 4141522: VTRNA 2-1 Promoter Methylation and HDL as Predictors of Excess Weight Loss After Bariatric Surgery: The Influence of Maternal Nutrition

Circulation

Circulation, Volume 150, Issue Suppl_1 , Page A4141522-A4141522, November 12, 2024. Bariatric surgery is an effective treatment for morbid obesity, with most patients achieving significant weight control within 1-2 years post-surgery. Quantitative pyrosequencing was performed on all patients.

Obesity 40
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The Importance of Cardiovascular Health: An Overview

GEMMS

Factors such as smoking, high blood pressure, high cholesterol levels, obesity, and a sedentary lifestyle significantly increase the risk of developing cardiovascular disease. Engaging in activities such as running, swimming, or cycling helps strengthen the heart, increase lung capacity, and improve blood circulation.

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Abstract TP268: Xylitol, Xylose, and MicroRNAs Associated with Thrombosis and the Clotting Cascade in a Multi-Omics Cross-Sectional Study of Adults at Risk for Type 2 Diabetes and Stroke

Stroke Journal

Older adults with obesity and metabolic syndrome may have decreased elimination of the xylitol metabolite xylose, which may explain the higher observed risk of thrombosis and stroke in older adults who consume foods with sugar alcohols. However, multiomics studies of both xylitol metabolites and these miRs in humans have not been done.

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AVCAPIR: A Novel Procalcific PIWI-Interacting RNA in Calcific Aortic Valve Disease

Circulation

Circulation, Ahead of Print. High-cholesterol diet–fed ApoE–/–mice with AVCAPIR knockout were used to examine the role of AVCAPIR in aortic valve calcification (AVC). BACKGROUND:Calcification of the aortic valve leads to increased leaflet stiffness and consequently results in the development of calcific aortic valve disease (CAVD).